|
1）Kleijnen MF, Shih AH, Zhou P, et al. The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome. Mol Cell. 2000; 6: 409-19
|
|
|
|
2）Buchberger A. From UBA to UBX: new words in the ubiquitin vocabulary. Trends Cell Biol. 2002; 12: 216-21
|
|
|
|
|
|
3）Stieren ES, El Ayadi A, Xiao Y, et al. Ubiquilin-1 is a molecular chaperone for the amyloid precursor protein. J Biol Chem. 2011; 286: 35689-98
|
|
|
|
|
|
4）Lim PJ, Danner R, Liang J, et al. Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. J Cell Biol. 2009; 187: 201-17
|
|
|
|
|
|
5）Deng HX, Chen W, Hong ST, et al. Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia. Nature. 2011; 477: 211-5
|
|
|
|
|
|
6）Osaka M, Ito D, Yagi T, et al. Evidence of a link between ubiquilin 2 and optineurin in amyotrophic lateral sclerosis. Hum Mol Genet. 2015; 24: 1617-29
|
|
|
|
|
|
7）Gorrie GH, Fecto F, Radzicki D, et al. Dendritic spinopathy in transgenic mice expressing ALS/dementia-linked mutant UBQLN2. Proc Natl Acad Sci U S A. 2014; 111: 14524-9
|
|
|
|
|
|
8）Cirulli ET, Lasseigne BN, Petrovski S, et al. Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways. Science. 2015; 347: 1436-41
|
|
|
|
|
|
9）Freischmidt A, Wieland T, Richter B, et al. Haplo-insufficiency of TBK1 causes familial ALS and fronto-temporal dementia. Nat Neurosci. 2015; 18: 631-6
|
|
|
|
|
|
10）Bertram L, Hiltunen M, Parkinson M, et al. Family-based association between Alzheimerʼs disease and variants in UBQLN1. N Engl J Med. 2005; 352: 884-94
|
|
|
|
|
|
11）Lagier-Tourenne C, Cleveland DW. Rethinking ALS: the FUS about TDP-43. Cell. 2009; 136: 1001-4
|
|
|
|
|
|
12）Fahed AC, McDonough B, Gouvion CM, et al. UBQLN2 mutation causing heterogeneous X-linked dominant neurodegeneration. Ann Neurol. 2014; 75: 793-8
|
|
|
|
|
|
13）Marin I. The ubiquilin gene family: evolutionary patterns and functional insights. BMC Evol Biol. 2014; 14: 63
|
|
|
|
|
|
14）Zhang KY, Yang S, Warraich ST, et al. Ubiquilin 2: a component of the ubiquitin-proteasome system with an emerging role in neurodegeneration. Int J Biochem Cell Biol. 2014; 50: 123-6
|
|
|
|
|
|
15）Feng P, Scott CW, Cho NH, et al. Kaposiʼs sarcoma-associated herpesvirus K7 protein targets a ubiquitin-like/ubiquitin-associated domain-containing protein to promote protein degradation. Mol Cell Biol. 2004; 24: 3938-48
|
|
|
|
|
|
16）El Ayadi A, Stieren ES, Barral JM, et al. Ubiquilin-1 regulates amyloid precursor protein maturation and degradation by stimulating K63-linked polyubiquitination of lysine 688. Proc Natl Acad Sci U S A. 2012; 109: 13416-21
|
|
|
|
|
|
17）Mah AL, Perry G, Smith MA, et al. Identification of ubiquilin, a novel presenilin interactor that increases presenilin protein accumulation. J Cell Biol. 2000; 151: 847-62
|
|
|
|
|
|
18）Dillen L, Van Langenhove T, Engelborghs S, et al. Explorative genetic study of UBQLN2 and PFN1 in an extended Flanders-Belgian cohort of frontotemporal lobar degeneration patients. Neuro-biol Aging. 2013; 34: 1711 e1-5
|
|
|
|
|
|
19）Maruyama H, Morino H, Ito H, et al. Mutations of optineurin in amyotrophic lateral sclerosis. Nature. 2010; 465: 223-6
|
|
|
|
|
|
20）Nagabhushana A, Chalasani ML, Jain N, et al. Regulation of endocytic trafficking of transferrin receptor by optineurin and its impairment by a glaucoma-associated mutant. BMC Cell Biol. 2010; 11: 4
|
|
|
|
|
|
21）Puri C, Renna M, Bento CF, et al. Diverse autophagosome membrane sources coalesce in recycling endosomes. Cell. 2013; 154: 1285-99
|
|
|
|
|
|
22）Longatti A, Lamb CA, Razi M, et al. TBC1D14 regulates autophagosome formation via Rab11- and ULK1-positive recycling endosomes. J Cell Biol. 2012; 197: 659-75
|
|
|
|
|
|
23）Ceballos-Diaz C, Rosario AM, Park HJ, et al. Viral expression of ALS-linked ubiquilin-2 mutants causes inclusion pathology and behavioral deficits in mice. Mol Neurodegener. 2015; 10: 25
|
|
|
|
|
|
24）Weidberg H, Elazar Z. TBK1 mediates crosstalk between the innate immune response and autophagy. Sci Signal. 2011; 4: pe39
|
|
|
|
|
|
25）Pottier C, Bieniek KF, Finch N, et al. Whole-genome sequencing reveals important role for TBK1 and OPTN mutations in frontotemporal lobar degeneration without motor neuron disease. Acta Neuropathol. 2015; 130: 77-92
|
|
|
|
|
|
26）Pilli M, Arko-Mensah J, Ponpuak M, et al. TBK-1 promotes autophagy-mediated antimicrobial defense by controlling autophagosome maturation. Immunity. 2012; 37: 223-34
|
|
|
|
|
|
27）Wild P, Farhan H, McEwan DG, et al. Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth. Science. 2011; 333: 228-33
|
|
|
|
|
|
28）Korac J, Schaeffer V, Kovacevic I, et al. Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates. J Cell Sci. 2013; 126: 580-92
|
|
|
|
|
|
29）Wathelet MG, Lin CH, Parekh BS, et al. Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo. Mol Cell. 1998; 1: 507-18
|
|
|
|
|