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1)Ohuchi H, Kagisaki K, Miyazaki A, et al. Impact of the evolution of the Fontan operation on early and late mortality: a single-center experience of 405 patients over 3 decades. Ann Thorac Surg. 2011; 92: 1457-66
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2)Hebson CL, McCabe NM, Elder RW, et al. Hemodynamic phenotype of the failing Fontan in an adult population. Am J Cardiol. 2013; 112: 1943-7
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3)Deal BJ, Jacobs ML. Management of the failing Fontan circulation. Heart. 2012; 98: 1098-104
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4)Ohuchi H, Ono S, Tanabe Y, et al. Long-term serial aerobic exercise capacity and hemodynamic properties in clinically and hemodynamically good, "excellent", Fontan survivors. Circ J. 2012; 76: 195-203
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5)Pike NA, Evangelista LS, Doering LV, et al. Clinical profile of the adolescent/adult Fontan survivor. Congenit Heart Dis. 2011; 6: 9-17
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6)Diller GP, Giardini A, Dimopoulos K, et al. Predictors of morbidity and mortality in contemporary Fontan patients: results from a multicenter study including cardiopulmonary exercise testing in 321 patients. Eur Heart J. 2010; 31: 3073-83
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7)Fernandes SM, Alexander ME, Graham DA, et al. Exercise testing identifies patients at increased risk for morbidity and mortality following Fontan surgery. Congenit Heart Dis. 2011; 6: 294-303
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8)Ohuchi H, Yasuda K, Miyazaki A, et al. Comparison of prognostic variables in children and adults with Fontan circulation. Int J Cardiol. 2014; 173: 277-83
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9)Ohuchi H, Miyazaki A, Wakisaka Y, et al. Systemic ventricular morphology-associated increased QRS duration compromises the ventricular mechano-electrical and energetic properties long-term after the Fontan operation. Int J Cardiol. 2009; 133: 371-80
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10)Griffiths ER, Kaza AK, Wyler von Ballmoos MC, et al. Evaluating failing Fontans for heart transplantation: predictors of death. Ann Thorac Surg. 2009; 88: 558-63
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11)Cheung YF, Penny DJ, Redington AN.Serial assessment of left ventricular diastolic function after Fontan procedure. Heart. 2000; 83: 420-4
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12)Westhoff-Bleck M, Norozi K, Schoof S, et al. QRS duration in Fontan circulation in adults: a predictor of aerobic capacity. Int J Cardiol. 2009; 132: 375-81
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13)Enomoto Y, Aoki M, Nakamura Y, et al. Successful Fontan completion after cardiac resynchronization therapy. Circulation. 2012; 125: e655-8
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14)Khairy P, Fernandes SM, Mayer JE Jr, et al. Long-term survival, modes of death, and predictors of mortality in patients with Fontan surgery. Circulation. 2008; 117: 85-92
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15)Solà E, Ginès P. Renal and circulatory dysfunction in cirrhosis: current management and future perspectives. J Hepatol. 2010; 53: 1135-45
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16)Ohuchi H, Yasuda K, Miyazaki A, et al. Haemodynamic characteristics before and after the onset of protein losing enteropathy in patients after the Fontan operation. Eur J Cardiothorac Surg. 2013; 43: e49-57
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17)John AS, Johnson JA, Khan M, et al. Clinical outcomes and improved survival in patients with protein-losing enteropathy after the Fontan operation. J Am Coll Cardiol. 2014; 64: 54-62
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18)Ohuchi H, Ohashi H, Takasugi H, et al. Restrictive ventilatory impairment and arterial oxygenation characterize rest and exercise ventilation in patients after fontan operation. Pediatr Cardiol. 2004; 25: 513-21
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19)Ohuchi H, Wakisaka Y, Watanabe K, et al. Impact of central hypercapnic chemosensitivity on enhanced ventilation in patients after the Fontan operation. Int J Cardiol. 2007; 121: 36-43
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20)von Känel R, Dimsdale JE. Effects of sympathetic activation by adrenergic infusions on hemostasis in vivo. Eur J Haematol. 2000; 65: 357-69
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21)Yasuma F, Hayano J. Respiratory sinus arrhythmia: why does the heartbeat synchronize with respiratory rhythm? Chest. 2004; 125: 683-90
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22)Ohuchi H, Hasegawa S, Yasuda K, et al. Severely impaired cardiac autonomic nervous activity after the Fontan operation. Circulation. 2001; 104: 1513-8
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23)Alonso-Gonzalez R, Borgia F, Diller GP, et al. Abnormal lung function in adults with congenital heart disease: prevalence, relation to cardiac anatomy, and association with survival. Circulation. 2013; 127: 882-90
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24)Opotowsky AR, Landzberg MJ, Earing MG, et al. Abnormal spirometry after the Fontan procedure is common and associated with impaired aerobic capacity. Am J Physiol. 2014; 307: H110-7
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25)Shafer KM, Garcia JA, Babb TG, et al. The importance of the muscle and ventilatory blood pumps during exercise in patients without a subpulmonary ventricle (Fontan operation). J Am Coll Cardiol. 2012; 60: 2115-21
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26)Ohuchi H, Watanabe K, Kishiki K, et al. Heart rate dynamics during and after exercise in postoperative congenital heart disease patients. Their relation to cardiac autonomic nervous activity and intrinsic sinus node dysfunction. Am Heart J. 2007; 154: 165-71
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27)Ohuchi H, Negishi J, Miyake A, et al. Long-term prognostic value of cardiac autonomic nervous activity in postoperative patients with congenital heart disease. Int J Cardiol. 2011; 151: 296-302
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28)Meadows J, Lang P, Marx G, et al. Fontan fenestration closure has no acute effect on exercise capacity but improves ventilatory response to exercise. J Am Coll Cardiol. 2008; 52: 108-13
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29)Bauer BS, Aboulhosn JA, Williams RJ, et al. Patients with single-ventricle physiology: prognostic implications of stress testing. Pediatr Cardiol. 2011; 32: 891-5
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30)Giardini A, Specchia S, Gargiulo G, et al. Accuracy of oxygen uptake efficiency slope in adults with congenital heart disease. Int J Cardiol. 2009; 133: 74-9
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