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3)Sonobe M, Yamazaki T, Yonekura M, et al. Small unruptured intracranial aneurysm verification study: SUAVe study, Japan. Stroke. 2010; 41: 1969-77
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5)Shojima M, Nemoto S, Morita A, et al. Role of shear stress in the blister formation of cerebral aneurysms. Neurosurgery. 2010; 67: 1268-74; discussion 74-5
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6)Miura Y, Ishida F, Umeda Y, et al. Low wall shear stress is independently associated with the rupture status of middle cerebral artery aneurysms. Stroke. 2013; 44: 519-21
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7)Yasuda R, Strother CM, Taki W, et al. Aneurysm volume-to-ostium area ratio: a parameter useful for discriminating the rupture status of intracranial aneurysms. Neurosurgery. 2011; 68: 310-7; discussion 7-8
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8)Korja M, Juvela S, Hernesniemi J. Unruptured cerebral aneurysms in a Japanese cohort. N Engl J Med. 2012; 367: 1268; author reply 9
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9)Shojima M, Oshima M, Takagi K, et al. Magnitude and role of wall shear stress on cerebral aneurysm: computational fluid dynamic study of 20 middle cerebral artery aneurysms. Stroke. 2004; 35: 2500-5
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10)Cebral JR, Mut F, Weir J, et al. Association of hemodynamic characteristics and cerebral aneurysm rupture. AJNR Am J Neuroradiol. 2011; 32: 264-70
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11)Meng H, Tutino VM, Xiang J, et al. High WSS or Low WSS? Complex Interactions of Hemodynamics with Intracranial Aneurysm Initiation, Growth, and Rupture: Toward a Unifying Hypothesis. AJNR Am J Neuroradiol. 2013. Epub 2013/04/20
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13)Tremmel M, Dhar S, Levy EI, et al. Influence of intracranial aneurysm-to-parent vessel size ratio on hemodynamics and implication for rupture: results from a virtual experimental study. Neurosurgery. 2009; 64: 622-30; discussion 30-1
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14)Unruptured intracranial aneurysms--risk of rupture and risks of surgical intervention. International Study of Unruptured Intracranial Aneurysms Investigators. N Engl J Med. 1998; 339: 1725-33
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15)Sato K, Yoshimoto Y. Risk profile of intracranial aneurysms: rupture rate is not constant after formation. Stroke. 2011; 42: 3376-81
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16)Lee EJ, Lee HJ, Hyun MK, et al. Rupture rate for patients with untreated unruptured intracranial aneurysms in South Korea during 2006-2009. J Neurosurg. 2012; 117: 53-9
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19)Asari S, Ohmoto T. Natural history and risk factors of unruptured cerebral aneurysms. Clin Neurol Neurosurg. 1993; 95: 205-14
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20)Inoue T, Shimizu H, Fujimura M, et al. Annual rupture risk of growing unruptured cerebral aneurysms detected by magnetic resonace angiography. J Neurosurg. 2012; 117: 20-5
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21)Huang MC, Baaj AA, Downes K, et al. Paradoxical trends in the management of unruptured cerebral aneurysms in the United States: analysis of nationwide database over a 10-year period. Stroke. 2011; 42: 1730-5
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22)Brinjikji W, Rabinstein AA, Lanzino G, et al. Patient outcomes are better for unruptured cerebral aneurysms treated at centers that preferentially treat with endovascular coiling: a study of the national inpatient sample 2001-2007. AJNR Am J Neuroradiol. 2011; 32: 1065-70
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23)Lylyk P, Miranda C, Ceratto R, et al. Curative endovascular reconstruction of cerebral aneurysms with the pipeline embolization device: the Buenos Aires experience. Neurosurgery. 2009; 64: 632-42; discussion 42-3; quiz N6
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24)Cebral JR, Mut F, Raschi M, et al. Aneurysm rupture following treatment with flow-diverting stents: computational hemodynamics analysis of treatment. AJNR Am J Neuroradiol. 2011; 32: 27-33
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25)Aoki T, Kataoka H, Shimamura M, et al. NF-kappaB is a key mediator of cerebral aneurysm formation. Circulation. 2007; 116: 2830-40
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26)Aoki T, Kataoka H, Ishibashi R, et al. Simvastatin suppresses the progression of experimentally induced cerebral aneurysms in rats. Stroke. 2008; 39: 1276-85
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27)Aoki T, Kataoka H, Nishimura M, et al. Regression of intracranial aneurysms by simultaneous inhibition of nuclear factor-kappaB and Ets with chimeric decoy oligodeoxynucleotide treatment. Neurosurgery. 2012; 70: 1534-43; discussion 43
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28)Makino H, Tada Y, Wada K, et al. Pharmacological stabilization of intracranial aneurysms in mice: a feasibility study. Stroke. 2012; 43: 2450-6
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29)Yoshimura Y, Murakami Y, Saitoh M, et al. Statin Use and Risk of Cerebral Aneurysm Rupture: A Hospital-Based Case-Control Study in Japan. J Stroke Cerebrovasc Dis. 2013. Epub 2013/05/24
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30)Hasan DM, Mahaney KB, Brown RD Jr, et al. Aspirin as a promising agent for decreasing incidence of cerebral aneurysm rupture. Stroke. 2011; 42: 3156-62
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31)Hasan DM, Chalouhi N, Jabbour P, et al. Evidence that acetylsalicylic acid attenuates inflammation in the walls of human cerebral aneurysms: preliminary results. J Am Heart Assoc. 2013; 2: e000019
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32)Nakano K, Hokamura K, Taniguchi N, et al. The collagen-binding protein of Streptococcus mutans is involved in haemorrhagic stroke. Nat Commun. 2011; 2: 485
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33)Lesniewski LA, Durrant JR, Connell ML, et al. Aerobic exercise reverses arterial inflammation with aging in mice. Am J Physiol Heart Circ Physiol. 2011; 301: H1025-32
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