1)Gershon AS, Warner L, Cascagnette P, et al. Lifetime risk of developing chronic obstructive pulmonary disease: a longitudinal population study. Lancet. 2011; 378: 991-6
|
|
|
2)Snider GL. Chronic obstructive pulmonary disease: risk factors, pathophysiology and pathogenesis. Annu Rev Med. 1989; 40: 411-9
|
|
|
3)Gerber HP, Dixit V, Ferrara N. Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells. J Biol Chem. 1998; 273; 13313-6
|
|
|
4)Alon T, Hemo I, Itin A, et al. Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity. Nat Med. 1995; 1: 1024-8
|
|
|
5)Kasahara Y, Tuder RM, Cool CD, et al. Endothelial cell death and decreased expression of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 in emphysema. Am J Respir Crit Care Med. 2001; 163: 737-44
|
|
|
6)Segura-Valdez L, Pardo A, Gaxiola M, et al. Upregulation of gelatinases A and B collagenases 1 and 2, and increased parenchymal cell death in COPD. Chest. 2000; 117: 684-94
|
|
|
7)Afford SC, Randhawa S, Eliopoulos AG, et al. CD40 activation induces apoptosis in cultured human hepatocytes via induction of cell surface fas ligand expression and amplifies fas-mediated hepatocyte death during allograft rejection. J Exp Med. 1999; 189: 441-6
|
|
|
8)Ping L, Ogawa N, Sugai S. Novel role of CD40 in Fas-dependent apoptosis of cultured salivary epithelial cells from patients with Sjögren’s syndrome. Arthritis Rheum. 2005; 52: 573-81
|
|
|
9)Eliopoulos AG, Davies C, Knox PG, et al. CD40 induces apoptosis in carcinoma cells through activation of cytotoxic ligands of the tumor necrosis factor superfamily. Mol Cell Biol. 2000; 20: 5503-15
|
|
|
10)Georgopoulos NT, Steele LP, Thomson MJ, et al. A novel mechanism of CD40-induced apoptosis of carcinoma cells involving TRAF3 and JNK/AP-1 activation. Cell Death Differ. 2006; 13: 1789-801
|
|
|
11)Karmann K, Hughes CC, Schechner J, et al. CD40 on human endothelial cells; inducibility by cytokines and functional regulation of adhesion molecule expression. Proc Natl Acad Sci U S A. 1995; 92: 4342-6
|
|
|
12)Hollenbaugh D, Mischel-Petty N, Edwards CP, et al. Expression of functional CD40 by vascular endothelial cells. J Exp Med. 1995; 182: 33-40
|
|
|
13)Sugiura T, Kawaguchi Y, Harigai M, et al. Increased CD40 expression on muscle cells of polymyositis and dermatomyositis: role of CD40-CD40 ligand interaction in IL-6, IL-8, IL-15, and monocyte chemoattractant protein-1 production. J Immunol. 2000; 164: 6593-600
|
|
|
14)Bruemmer D, Riggers U, Holzmeister J, et al. Expression of CD40 in vascular smooth muscle cells and macrophages is associated with early development of human atherosclerotic lesions. Am J Cardiol. 2001; 87: 21-7
|
|
|
15)Henn V, Slupsky J, Grafe M, et al. CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells. Nature. 1998; 391: 591-4
|
|
|
16)Henn V, Steinbach S, Buchner K, et al. The inflammatory action of CD40 ligand (CD154) expressed on activated human platelets is temporally limited by coexpressed CD40. Blood. 2001; 98: 1047-54
|
|
|
17)Anand SX, Viles-Gonzalez JF, Badimon JJ, et al. Membrane-associated CD40L and sCD40L in atherothrombotic disease. Thromb Haemost. 2003; 90: 377-84
|
|
|
18)Kotowicz K, Dixon GL, Klein NJ, et al. Biological function of CD40 on human endothelial cells: costimulation with CD40 ligand and interleukin-4 selectively induces expression of vascular cell adhension molecule-1 and P-selectin resulting in preferential adhesion of lymphocytes. Immunology. 2000; 100: 441-8
|
|
|
19)Patrick A, Lisa N, Srinivasa K, et al. Platelet-derived CD40L: the switch-hitting player of cardiovascular disease. Circulation. 2002; 106: 896-9
|
|
|
20)Walter RE, Wilk JB, Larson MG, et al. Systemic inflammation and COPD: the Framingham Heart Study. Chest. 2008; 133: 19-25
|
|
|
21)Harding SA, Sarma J, Josephs DH, et al. Upregulation of the CD40/CD40 ligand dyad and platelet-monocyte aggregation in cigarette smokers. Circulation. 2004; 109: 1926-9
|
|
|
22)Tripp RA, Jones L, Anderson LJ, et al. CD40 ligand (CD154) enhances the Th1 and antibody responses to respiratory syncytial virus in the BALB/c mouse. J Immunol. 2000; 154: 5913-21
|
|
|
23)Chakrabarti S, Rizvi M, Pathak D, et al. Hypoxia influences CD40-CD40L mediated inflammation in endothelial and monocytic cells. Immunol Lett. 2009; 122: 170-84
|
|
|
24)Saetta M. Airway inflammation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 1999; 160: S21-5
|
|
|
25)Saetta M, Baraldo S, Corbino L, et.al. CD8+ve cells in the lungs of smokers with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 1999; 160: 711-7
|
|
|
26)O’Shaughnessy TC, Ansari TW, Barnes NC, et al. Inflammation in bronchial biopsies of subjects with chronic bronchitis: inverse relationship of CD8+T lymphocytes with FEV1. Am J Respir Crit Care Med. 1997; 155: 852-7
|
|
|
27)Ma B, Kang MJ, Lee CG, et al. Role of CCR5 in IFN-gamma-induced and cigarette smoke-induced emphysema. J Clin Invest. 2005; 115: 3469-72
|
|
|
28)Hollenbaugh D, Mischel-Petty N, Edwards CP, et al. Expression of functional CD40 by vascular endothelial cells. J Exp Med. 1995; 182: 33-40
|
|
|