1)Ruiz FA, Lea CR, Oldfield E, et al. Human platelet dense granules contain polyphosphate and are similar to acidocalcisomes of bacteria and unicellular eukaryotes. J Biol Chem. 2004; 279: 44250-7
|
|
|
2)Smith SA, Mutch NJ, Baskar D, et al. Polyphosphate modulates blood coagulation and fibrinolysis. Proc Natl Acad Sci U S A. 2006; 103: 903-8
|
|
|
3)Muller F, Mutch NJ, Schenk WA, et al. Platelet polyphosphates are proinflammatory and procoagulant mediators in vivo. Cell. 2009; 139: 1143-56
|
|
|
4)Morrissey JH. Polyphosphate: a link between platelets, coagulation and inflammation. Int J Hematol. 2012; 95: 346-52
|
|
|
5)Morrissey JH, Choi SH, Smith SA. Polyphosphate: an ancient molecule that links platelets, coagulation, and inflammation. Blood. 2012; 119: 5972-9
|
|
|
6)Brown MR, Kornberg A. Inorganic polyphosphate in the origin and survival of species. Proc Natl Acad Sci U S A. 2004; 101: 16085-7
|
|
|
7)Hernandez-Ruiz L, Saez-Benito A, Pujol-Moix N, et al. Platelet inorganic polyphosphate decreases in patients with delta storage pool disease. J Thromb Haemost. 2009; 7: 361-3
|
|
|
8)Xu J, Zhang X, Pelayo R, et al. Extracellular histones are major mediators of death in sepsis. Nat Med. 2009; 15: 1318-21
|
|
|
9)Fuchs TA, Brill A, Duerschmied D, et al. Extracellular DNA traps promote thrombosis. Proc Natl Acad Sci U S A. 2010; 107: 15880-5
|
|
|
10)Caen J, Wu Q. Hageman factor, platelets and polyphosphates: early history and recent connection. J Thromb Haemost. 2010; 8: 1670-4
|
|
|
11)Mutch NJ, Myles T, Leung LLK, et al. Polyphosphate binds with high affinity to exosite II of thrombin. J Thromb Haemost. 2010; 8: 548-55
|
|
|
12)Naito K, Fujikawa K. Activation of human blood coagulation factor XI independent of factor XII. Factor XI is activated by thrombin and factor XIa in the presence of negatively charged surfaces. J Biol Chem. 1991; 266: 7353-8
|
|
|
13)Gailani D, Broze GJ, Jr. Factor XI activation in a revised model of blood coagulation. Science. 1991; 253: 909-12
|
|
|
14)Choi SH, Smith SA, Morrissey JH. Polyphosphate is a cofactor for the activation of factor XI by thrombin. Blood. 2011; 118: 6963-70
|
|
|
15)Mutch NJ, Engel R, de Willige SU, et al. Polyphosphate modifies the fibrin network and down-regulates fibrinolysis by attenuating binding of tPA and plasminogen to fibrin. Blood. 2010; 115: 3980-8
|
|
|
16)Smith SA, Morrissey JH. Polyphosphate enhances fibrin clot structure. Blood. 2008; 112: 2810-6
|
|
|
17)Montilla M, Hernandez-Ruiz L, Garcia-Cozar FJ, et al. Polyphosphate binds to human von Willebrand factor in vivo and modulates its interaction with glycoprotein Ib. J Thromb Haemost. 2012; 10: 2315-23
|
|
|
18)Smith SA, Choi SH, Davis-Harrison R, et al. Polyphosphate exerts differential effects on blood clotting, depending on polymer size. Blood. 2010; 116: 4353-9
|
|
|
19)Muhl L, Galuska SP, Oorni K, et al. High negative charge-to-size ratio in polyphosphates and heparin regulates factor VII-activating protease. FEBS J. 2009; 276: 4828-39
|
|
|
20)Jain S, Pitoc GA, Holl EK, et al. Nucleic acid scavengers inhibit thrombosis without increasing bleeding. Proc Natl Acad Sci U S A. 2012; 109: 12938-43
|
|
|
21)Smith SA, Choi SH, Collins JNR, et al. Inhibition of polyphosphate as a novel strategy for preventing thrombosis and inflammation. Blood. 2012; 120: 5103-10
|
|
|
22)Ghosh S, Shukla D, Suman K, et al. Inositol hexakisphosphate kinase 1 maintains hemostasis in mice by regulating platelet polyphosphate levels. Blood. 2013; 122: 1478-86
|
|
|
23)Moreno-Sanchez D, Hernandez-Ruiz L, Ruiz FA, et al. Polyphosphate is a novel pro-inflammatory regulator of mast cells and is located in acidocalcisomes. J Biol Chem. 2012; 287: 28435-44
|
|
|
24)Rao NN, Gomez-Garcia MR, Kornberg A. Inorganic polyphosphate: Essential for growth and survival. Annu Rev Biochem. 2009; 78: 605-47
|
|
|
25)Semeraro F, Ammollo CT, Morrissey JH, et al. Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet TLR2 and TLR4. Blood. 2011; 118: 1952-61
|
|
|
26)Bae JS, Lee W, Rezaie AR. Polyphosphate elicits pro-inflammatory responses that are counteracted by activated protein C in both cellular and animal models. J Thromb Haemost. 2012; 10: 1145-51
|
|
|