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1)Krum H, Schlaich M, Whitbourn R, et al. Catheter-based renal sympathetic denervation for resistant hypertension: a multicentre safety and proof-of-principle cohort study. Lancet. 2009; 373: 1275-81
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2)Symplicity HTN-2 Investigators. Renal sympathetic denervation in patients with treatment-resistant hypertension (The Symplicity HTN-2 Trial): a randomised controlled trial. Lancet. 2010; 376: 1903-9
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3)Campese VM, Kogosov E. Renal afferent denervation prevents hypertension in rats with chronic renal failure. Hypertension. 1995; 25: 878-82
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4)Grassi G, Quarti-Trevano F, Seravalle G, et al. Early sympathetic activation in the initial clinical stages of chronic renal failure. Hypertension. 2011; 57: 846-51
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5)Grassi G. Assessment of sympathetic cardiovascular drive in human hypertension, achievements and perspectives, Hypertension. 2009; 54: 690-7
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6)Schlaich MP, Sobotka PA, Krum H, et al. Renal sympathetic-nerve ablation for uncontrolled hypertension. N Engl J Med. 2009; 361: 932-4
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7)Brinkmann J, Heusser K, Schmidt BM, et al. Catheter-based renal nerve ablation and centrally generated sympathetic activity in difficult-to-control hypertensive patients: prospective case series. Hypertension. 2012; 60: 1485-90
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8)Katholi RE, Rocha-Singh KJ, Goswami NJ, et al. Renal nerves in the maintenance of hypertension: a potential therapeutic target. Curr Hypertens Rep. 2010; 12: 196-204
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9)Mancia G, Bousquet P, Elghozi JL, et al. The sympathetic nervous system and the metabolic syndrome. J Hypertens. 2007; 25: 909-20
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10)Mahfoud F, Schlaich M, Kindermann I, et al. Effect of renal sympathetic denervation on glucose metabolism in patients with resistant hypertension: a pilot study. Circulation. 2011; 123: 1940-6
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11)Witkowski A, Prejbisz A, Florczak E, et al. Effects of renal sympathetic denervation on blood pressure, sleep apnea course, and glycemic control in patients with resistant hypertension and sleep apnea. Hypertension. 2011; 58: 559-65
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12)Brandt MC, Mahfoud F, Reda S, et al. Renal sympathetic denervation reduces left ventricular hypertrophy and improves cardiac function in patients with resistant hypertension. J Am Coll Cardiol. 2012; 59: 901-9
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13)Davies JE, Manisty CH, Petraco R, et al. First-in-man safety evaluation of renal denervation for chronic systolic heart failure: Primary outcome from REACH-Pilot study. Int J Cardiol. 2013: 162: 189-92
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14)Petidis K, Anyfanti P, Doumas M. Renal sympathetic denervation: renal function concerns. Hypertension. 2011; 58: e19
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15)Hering D, Mahfoud F, Walton AS, et al. Renal denervation in moderate to severe CKD. J Am Soc Nephrol. 2012; 23: 1250-7
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16)Mahfoud F, Cremers B, Janker J, et al. Renal hemodynamics and renal function after catheter-based renal sympathetic denervation in patients with resistant hypertension. Hypertension. 2012; 60: 419-24
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17)Pokushalov E, Romanov A, Corbucci G, et al. A randomized comparison of pulmonary vein isolation with versus without concomitant renal artery denervation in patients with refractory symptomatic atrial fibrillation and resistant hypertension. J Am Coll Cardiol. 2012; 60: 1163-70
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18)Ahmed H, Miller MA, Dukkipati SR, et al. Adjunctive renal sympathetic denervation to modify hypertension as upstream therapy in the treatment of atrial fibrillation (H-FIB) study: Clinical background and study design. J Cardiovasc Electrophysiol. 2013; 24: 503-9
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19)Linz D, Wirth K, Ukena C, et al. Renal denervation suppress ventricular arrhythmias during acute ventricular ischemia in pigs. Heart Rhythm. 2013; 10: 1525-30
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