|
1）Barisoni L, Schnaper HW, Kopp JB. A proposed taxonomy for the podocytopathies: a reassessment of the primary nephrotic diseases. Clin J Am Soc Nephrol. 2007; 2: 529-42
|
|
|
|
2）Li Y, Kang YS, Dai C, et al. Epithelial-to-mesenchymal transition is a potential pathway leading to podocyte dysfunction and proteinuria. Am J Pathol. 2008; 172: 299-308
|
|
|
|
|
|
3）Mundel P, Reiser J, Kriz W. Induction of differentiation in cultured rat and human podocytes. J Am Soc Nephrol. 1997; 8: 697-705
|
|
|
|
|
|
4）Hsu HH, Hoffmann S, Endlich N, et al. Mechanisms of angiotensin II signaling on cytoskeleton of podocytes. J Mol Med (Berl). 2008; 86: 1379-94
|
|
|
|
|
|
5）Dai HY, Zheng M, Lv LL, et al. The roles of connective tissue growth factor and integrin-linked kinase in high glucose-induced phenotypic alterations of podocytes. J Cell Biochem. 2012; 113: 293-301
|
|
|
|
|
|
6）Liu Y. New insights into epithelial-mesenchymal transition in kidney fibrosis. J Am Soc Nephrol. 2010; 21: 212-22
|
|
|
|
|
|
7）Reik W. Stability and flexibility of epigenetic gene regulation in mammalian development. Nature. 2007 24; 447: 425-32
|
|
|
|
|
|
8）Portela A, Esteller M. Epigenetic modifications and human disease. Nat Biotechnol. 2010; 28: 1057-68
|
|
|
|
|
|
9）Mali P, Chou BK, Yen J, et al. Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes. Stem Cells. 2010; 28: 713-20
|
|
|
|
|
|
10）Ou JN, Torrisani J, Unterberger A, et al. Histone deacetylase inhibitor Trichostatin A induces global and gene-specific DNA demethylation in human cancer cell lines. Biochem Pharmacol. 2007; 73: 1297-307
|
|
|
|
|
|
11）Bechtel W, McGoohan S, Zeisberg EM, et al. Methylation determines fibroblast activation and fibrogenesis in the kidney. Nat Med. 2010; 16: 544-50
|
|
|
|
|
|
12）Sun G, Reddy MA, Yuan H, et al. Epigenetic histone methylation modulates fibrotic gene expression. J Am Soc Nephrol. 2010; 21: 2069-80
|
|
|
|
|
|
13）Marumo T, Hishikawa K, Yoshikawa M, et al. Epigenetic regulation of BMP7 in the regenerative response to ischemia. J Am Soc Nephrol. 2008; 19: 1311-20
|
|
|
|
|
|
14）Cardinale JP, Sriramula S, Pariaut R, et al. HDAC inhibition attenuates inflammatory, hypertrophic, and hypertensive responses in spontaneously hypertensive rats. Hypertension. 2010; 56: 437-44
|
|
|
|
|
|
15）Reddy MA, Natarajan R. Epigenetics in diabetic kidney disease. J Am Soc Nephrol. 2011; 22: 2182-5
|
|
|
|
|
|
16）Van Beneden K, Geers C, Pauwels M, et al. Valproic acid attenuates proteinuria and kidney injury. J Am Soc Nephrol. 2011; 22: 1863-75
|
|
|
|
|
|
17）Cianciolo Cosentino C, Skrypnyk NI, Brilli LL, et al. Histone deacetylase inhibitor enhances re-covery after AKI. J Am Soc Nephrol. 2013; 24: 943-53
|
|
|
|
|
|
18）Zhong Y, Chen EY, Liu R, et al. Renoprotective effect of combined inhibition of Angiotensin-converting enzyme and histone deacetylase. J Am Soc Nephrol. 2013; 24: 801-11
|
|
|
|
|
|
19）Dang DT, Pevsner J, Yang VW. The biology of the mammalian Kruppel-like family of transcription factors. Int J Biochem Cell Biol. 2000; 32: 1103-21
|
|
|
|
|
|
20）Katz JP, Perreault N, Goldstein BG, et al. The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon. Development. 2002; 129: 2619-28
|
|
|
|
|
|
21）Segre JA, Bauer C, Fuchs E. Klf4 is a transcription factor required for establishing the barrier function of the skin. Nat Genet. 1999; 22: 356-60
|
|
|
|
|
|
22）Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell. 2006; 126: 663-76
|
|
|
|
|
|
23）Takahashi K, Tanabe K, Ohnuki M, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell. 2007; 131: 861-72
|
|
|
|
|
|
24）Maherali N, Ahfeldt T, Rigamonti A, et al. A high-efficiency system for the generation and study of human induced pluripotent stem cells. Cell Stem Cell. 2008; 3: 340-5
|
|
|
|
|
|
25）Aoi T, Yae K, Nakagawa M, et al. Generation of pluripotent stem cells from adult mouse liver and stomach cells. Science. 2008; 321: 699-702
|
|
|
|
|
|
26）Li R, Liang J, Ni S, et al. A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts. Cell Stem Cell. 2010; 7: 51-63
|
|
|
|
|
|
27）Bhutani N, Brady JJ, Damian M, et al. Reprogramming towards pluripotency requires AID-dependent DNA demethylation. Nature. 2010; 463: 1042-7
|
|
|
|
|
|
28）Mallipattu SK, Liu R, Zheng F, et al. Kruppel-like factor 15（KLF15）is a key regulator of podocyte differentiation. J Biol Chem. 2012; 287: 19122-35
|
|
|
|
|
|
29）Cohen CD, Klingenhoff A, Boucherot A, et al. Comparative promoter analysis allows de novo identification of specialized cell junction-associated proteins. Proc Natl Acad Sci U S A. 2006; 103: 5682-7
|
|
|
|
|
|
30）Hong Q, Li C, Xie Y, et al. Kruppel-like factor-15 inhibits the proliferation of mesangial cells. Cell Physiol Biochem. 2012; 29: 893-904
|
|
|
|
|
|
31）Slater SC, Ramnath RD, Uttridge K, et al. Chronic exposure to laminar shear stress induces Kruppel-like factor 2 in glomerular endothelial cells and modulates interactions with co-cultured podocytes. Int J Biochem Cell Biol. 2012; 44: 1482-90
|
|
|
|
|
|
32）Qi W, Chen X, Holian J, et al. Transcription factors Kruppel-like factor 6 and peroxisome proliferator-activated receptor-{gamma} mediate high glucose-induced thioredoxin-interacting protein. Am J Pathol. 2009; 175: 1858-67
|
|
|
|
|
|
33）Fujiu K, Manabe I, Nagai R. Renal collecting duct epithelial cells regulate inflammation in tubulointerstitial damage in mice. J Clin Invest. 2011; 121: 3425-41
|
|
|
|
|