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2)Matsuzaki K, Suzuki Y, Nakata J, et al. Nationwide survey on current treatments for IgA nephropathy in Japan. Clin Exp Nephrol. 2013 [Epub ahead of print]
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3)Wang Y, Chen J, Wang Y, et al. A meta-analysis of the clinical remission rate and long-term efficacy of tonsillectomy in patients with IgA nephropathy. Nephrol Dial Transplant. 2011; 26: 1923-31
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4)Suzuki Y, Tomino Y. The mucosa-bone-marrow axis in IgA nephropathy. Contrib Nephrol. 2007; 157: 70-9. Review
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5)van den Wall Bake AW, Daha MR, van Es LA. Immunopathogenetic aspects of IgA nephropathy. Nephrologie. 1989; 10: 141-5. Review
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6)Suzuki Y, Tomino Y. Potential immunopathogenic role of the mucosa-bone marrow axis in IgA nephropathy: insights from animal models. Semin Nephrol. 2008; 28: 66-77
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9)Kroese FG, Butcher EC, Stall AM, et al. Many of the IgA producing plasma cells in murine gut are derived from self-replenishing precursors in the peritoneal cavity. Int Immunol. 1989; 1: 75-84
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10)Macpherson AJ, Gatto D, Sainsbury E, et al. A primitive T cell-independent mechanism of intestinal mucosal IgA responses to commensal bacteria. Science. 2000; 288: 2222-6
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11)He B, Xu W, Santini PA, et al. Intestinal bacteria trigger T cell-independent immunoglobulin A(2) class switching by inducing epithelial-cell secretion of the cytokine APRIL. Immunity. 2007; 26: 812-26
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12)Cyster JG. Homing of antibody secreting cells. Immunol Rev. 2003; 194: 48-60
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13)Nakayama T, Hieshima K, Izawa D, et al. Cutting edge: profile of chemokine receptor expression on human plasma cells accounts for their efficient recruitment to target tissues. J Immunol. 2003; 170: 1136-40
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14)Lazarus NH, Kunkel EJ, Johnston B, et al. A common mucosal chemokine (mucosae-associated epithelial chemokine/CCL28) selectively attracts IgA plasmablasts. J Immunol. 2003; 170: 3799-805
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15)Kunkel EJ, Kim CH, Lazarus NH, et al. CCR10 expression is a common feature of circulating and mucosal epithelial tissue IgA Ab-secreting cells. J Clin Invest. 2003; 111: 1001-10
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16)Harper SJ, Pringle JH, Wicks AC, et al. Expression of J chain mRNA in duodenal IgA plasma cells in IgA nephropathy. Kidney Int. 1994; 45: 836-44
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17)Westberg NG, Baklien K, Schmekel B, et al. Quantitation of immunoglobulin-producing cells in small intestinal mucosa of patients with IgA nephropathy. Clin Immunol Immunopathol. 1983; 26: 442-5
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18)van den Wall Bake AW, Daha MR, Evers-Schouten J, et al. Serum IgA and the production of IgA by peripheral blood and bone marrow lymphocytes in patients with primary IgA nephropathy: evidence for the bone marrow as the source of mesangial IgA. Am J Kidney Dis. 1988; 12: 410-4
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19)Layward L, Finnemore AM, Allen AC, et al. Systemic and mucosal IgA responses to systemic antigen challenge in IgA nephropathy. Clin Immunol Immunopathol. 1993; 69: 306-13
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20)van den Wall Bake AW, Beyer WE, Evers-Schouten JH, et al. Humoral immune response to influenza vaccination in patients with primary immunoglobulin A nephropathy. An analysis of isotype distribution and size of the influenza-specific antibodies. J Clin Invest. 1989; 84: 1070-5
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21)Mei HE, Yoshida T, Sime W, et al. Blood-borne human plasma cells in steady state are derived from mucosal immune responses. Blood. 2009; 113: 2461-9
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22)Fernandes JR, Snider DP. Polymeric IgA-secreting and mucosal homing pre-plasma cells in normal human peripheral blood. Int Immunol. 2010; 22: 527-40
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23)Suzuki H, Suzuki Y, Yamanaka T, et al. Genome-wide scan in a novel IgA nephropathy model identifies a susceptibility locus on murine chromosome 10, in a region syntenic to human IGAN1 on chromosome 6q22-23. J Am Soc Nephrol. 2005; 16: 1289-99
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24)Okazaki K, Suzuki Y, Otsuji M, et al. Development of a model of early-onset IgA nephropathy. J Am Soc Nephrol. 2012; 23: 1364-74
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25)Suzuki H, Suzuki Y, Aizawa M, et al. Th1 polarization in murine IgA nephropathy directed by bone marrow-derived cells. Kidney Int. 2007; 72: 319-27
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26)Aizawa M, Suzuki Y, Suzuki H, et al. Roles of bone marrow, mucosa and lymphoid tissues in pathogenesis of murine IgA nephropathy. Contrib Nephrol. 2007; 157: 164-8
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27)Nakata J, Suzuki Y, Suzuki H, et al. Experimental evidence of cell dissemination playing a role in pathogenesis of IgA nephropathy in multiple lymphoid organs. Nephrol Dial Transplant. 2013; 28: 320-6
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28)Suzuki H, Suzuki Y, Narita I, et al. Toll-like receptor 9 affects severity of IgA nephropathy. J Am Soc Nephrol. 2008; 19: 2384-95
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29)Kajiyama T, Suzuki Y, Kihara M, et al. Different pathological roles of toll-like receptor 9 on mucosal B cells and dendritic cells in murine IgA nephropathy. Clin Dev Immunol. 2011; 2011: 819646
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30)Sato D, Suzuki Y, Kano T, et al. Tonsillar TLR9 expression and efficacy of tonsillectomy with steroid pulse therapy in IgA nephropathy patients. Nephrol Dial Transplant. 2012; 27: 1090-7
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31)Kodama S, Suzuki M, Arita M, et al. Increase in tonsillar germinal centre B-1 cell numbers in IgA nephropathy (IgAN) patients and reduced susceptibility to Fas-mediated apoptosis. Clin Exp Immunol. 2001; 123: 301-8
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32)Yuling H, Ruijing X, Xiang J, et al. CD19+CD5+ B cells in primary IgA nephropathy. J Am Soc Nephrol. 2008; 19: 2130-9
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33)Batra A, Smith AC, Feehally J, et al. T-cell homing receptor expression in IgA nephropathy. Nephrol Dial Transplant. 2007; 22: 2540-8
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34)Sisirak V, Vey N, Vanbervliet B, et al. CCR6/CCR10-mediated plasmacytoid dendritic cell recruitment to inflamed epithelia after instruction in lymphoid tissues. Blood. 2011; 118: 5130-40
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35)Sigurdardottir SL, Thorleifsdottir RH, Valdimarsson H, et al. The association of sore throat and psoriasis might be explained by histologically distinctive tonsils and increased expression of skin-homing molecules by tonsil T cells. Clin Exp Immunol. 2013; 174: 139-51
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