|
1）Weinman EJ, Lederer ED. NHERF-1 and the regulation of renal phosphate reabsorption: a tale of three hormones. Am J Physiol Renal Physiol. 2012; 303: F321-7
|
|
|
|
2）Biber J, Hernando N, Forster I, et al. Regulation of phosphate transport in proximal tubules. Pfluger Arch. 2009; 458: 39-52
|
|
|
|
|
|
3）Beck L, Karaplis AC, Amizuka N, et al. Targeted inactivation of Npt2 in mice leads to severe renal phosphate wasting, hypercalciuria, and skeletal abnormalities. Proc Natl Acad Sci U S A. 1998: 95: 5372-7
|
|
|
|
|
4）Segawa H, Kaneko I, Takahashi A, et al. Growth-related renal type II Na/Pi cotransporter. J Biol Chem. 2002; 277: 19665-72
|
|
|
|
|
|
5）Segawa H, Onitsuka A, Kuwahata M, et al. Type IIc sodium-dependent phosphate transporter regulates calcium metabolism. J Am Soc Nephrol. 2009; 20: 104-13
|
|
|
|
|
|
6）Segawa H, Aranami F, Kaneko I, et al. The roles of Na/Pi-II transporters in phosphate metabolism. Bone. 2009; 45: S2-7
|
|
|
|
|
|
7）Collins JF, Bai L, Ghishan FK. The SLC20 family of proteins: dual functions as sodium-phosphate cotransporters and viral receptors. Pfluger Arch. 2004; 447: 647-52
|
|
|
|
|
|
8）Tsukita S, Yonemura S. Cortical actin organization: lessons from ERM (ezrin/radixin/moesin) proteins. J Biol Chem. 1999; 274: 34507-10
|
|
|
|
|
|
9）Mahon MJ. Ezrin promotes functional expression and parathyroid hormone-mediated regulation of the sodium-phosphate cotransporter 2a in LLC-PK1 cells. Am J Physiol Renal Physiol. 2008; 294: F667-75
|
|
|
|
|
|
10）Shenolikar S, Voltz JW, Minkoff CM, et al. Targeted disruption of the mouse NHERF-1 gene promotes internalization of proximal tubule sodium-phosphate cotransporter type IIa and renal phosphate wasting. Proc Natl Acad Sci U S A. 2002; 99: 11470-5
|
|
|
|
|
|
11）Tamura A, Kikuchi S, Hata M, et al. Achlorhydria by ezrin knockdown: defects in the formation and expansion of apical canaliculi in gastric parietal cells. J Cell Biol. 2005; 169: 21-8
|
|
|
|
|
|
12）Hatano R, Fujii E, Segawa H, et al. Ezrin, a membrane cytoskeletal cross-linker, is essential for the regulation of phosphate and calcium homeostasis. Kidney Int. 2013; 83: 41-9
|
|
|
|
|
|
13）Weinman EJ, Steplock D, Zhang Y, et al. Cooperativity between the phosphorylation of Thr95 and Ser77 of NHERF-1 in the hormonal regulation of renal phosphate transport. J Biol Chem. 2010; 285: 25134-8
|
|
|
|
|
|
14）Weinman EJ, Biswas RS, Peng Q, et al. Parathyroid hormone inhibits renal phosphate transport by phosphorylation of serine 77 of sodium-hydrogen exchanger regulatory factor-1. J Clin Invest. 2007; 117: 3412-20
|
|
|
|
|
|
15）Weinman EJ, Biswas R, Steplock D, et al. Increased renal dopamine and acute renal adptation to a high-phosphate diet. Am J Physiol Renal Physiol. 2011; 300: F1123-9
|
|
|
|
|
|
16）Weinman EJ, Biswas R, Steplock D, et al. Sodium-hydrogen exchanger regulatory factor 1 (NHERF1) transduces signals that mediate dopamine inhibition of sodium- phosphate cotransport in mouse kidney. J Biol Chem. 2010; 285: 13454-60
|
|
|
|
|
|
17）Wolf M. Update on fibroblast growth factor 23 in chronic kidney disease. Kidney Int. 2012; 82: 737-47
|
|
|
|
|
|
18）Shimada T, Muto T, Urakawa I, et al. Mutant FGF-23 responsible for autosomal dominant hypophosphatemic rickets is resistant to proteolytic cleavage and causes hypophosphatemia in vivo. Endocrinology. 2002; 143: 3179-82
|
|
|
|
|
|
19）Shimada T, Kakitani M, Yamazaki Y, et al. Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism. J Clin Invest. 2004; 113: 561-8
|
|
|
|
|
|
20）Ferrari SL, Bonjour J-P, Rizzoli R. Fibroblast growth factor-23 relationship to dietary phosphate and renal phosphate handling in healthy young men. J Clin Endocrinol Metab. 2005; 90: 1519-24
|
|
|
|
|
|
21）The ADHR Consortium. Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23. Nat Genet. 2000; 26: 345-8
|
|
|
|
|
|
22）The HYP Consortium. A gene (PEX) with homologies to endopeptidases is mutated in patients with X-linked hypophosphatemic rickets. Nat Genet. 1995; 11: 130-6
|
|
|
|
|
|
23）Yuan B, Takaiwa M, Clemens TL, et al. Aberrant Phex function in osteoblasts and osteocytes alone underlies murine X-linked hypophosphatemia. J Clin Invest. 2008; 118: 722-34
|
|
|
|
|
|
24）Benet-Pagès A, Orlik P, Strom TM, et al. An FGF23 missense mutation causes familial tumoral calcinosis with hyperphosphatemia. Hum Mol Genet. 2005; 14: 385-90
|
|
|
|
|
|
25）Larsson T, Nisbeth U, Ljunggren Ö, et al. Circulating concentration of FGF-23 increases as renal function declines in patients with chronic kidney disease, but does not change in response to variation in phosphate intake in healthy volunteers. Kidney Int. 2003; 64: 2272-9
|
|
|
|
|
|
26）Weinman EJ, Steplock D, Shenolikar S, et al. Fibroblast growth factor-23-mediated inhibition of renal phosphate transport in mice requires sodium-hydrogen exchanger regulatory factor-1 (NHERF-1) and synergizes with parathyroid hormone. J Biol Chem. 2011; 286: 37216-21
|
|
|
|
|
|
27）Blaine J, Okamura K, Giral H, et al. PTH-induced internalization of apical membrane NaPi2a: role of actin and myosin VI. Am J Physiol Cell Physiol. 2009; 297: C1339-46
|
|
|
|
|