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1)Schroder M, Kaufman RJ. The mammalian unfolded protein response. Annu Rev Biochem. 2005; 74: 739-89
PubMed CrossRef
医中誌リンクサービス
2)Ron D, Habener JF. CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription. Genes Dev. 1992; 6: 439-53
PubMed CrossRef
医中誌リンクサービス
3)Oyadomari S, Koizumi A, Takeda K, et al. Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes. J Clin Invest. 2002; 109: 525-32
PubMed
医中誌リンクサービス
4)McCullough KD, Martindale JL, Klotz LO, et al. Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state. Mol Cell Biol. 2001; 21: 1249-59
PubMed CrossRef
医中誌リンクサービス
5)Murphy KM, Ranganathan V, Farnsworth ML, et al. Bcl-2 inhibits Bax translocation from cytosol to mitochondria during drug-induced apoptosis of human tumor cells. Cell Death Differ. 2000; 7: 102-11
PubMed CrossRef
医中誌リンクサービス
6)Zong WX, Li C, Hatzivassiliou G, et al. Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis. J Cell Biol. 2003; 162: 59-69
PubMed CrossRef
医中誌リンクサービス
7)Urano F, Wang X, Bertolotti A, et al. Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1. Science. 2000; 287: 664-6
PubMed
医中誌リンクサービス
8)Nishitoh H, Saitoh M, Mochida Y, et al. ASK1 is essential for JNK/SAPK activation by TRAF2. Mol Cell. 1998; 2: 389-95
PubMed CrossRef
医中誌リンクサービス
9)Nakagawa T, Zhu H, Morishima N, et al. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature. 2000; 403: 98-103
PubMed
医中誌リンクサービス
10)Lipson KL, Fonseca SG, Ishigaki S, et al. Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1. Cell Metab. 2006; 4: 245-54
PubMed CrossRef
医中誌リンクサービス
11)Elouil H, Bensellam M, Guiot Y, et al. Acute nutrient regulation of the unfolded protein response and integrated stress response in cultured rat pancreatic islets. Diabetologia. 2007; 50: 1442-52
PubMed CrossRef
医中誌リンクサービス
12)Jonas JC, Bensellam M, Duprez J, et al. Glucose regulation of islet stress responses and beta-cell failure in type 2 diabetes. Diabetes Obes Metab. 2009; 11 Suppl 4: 65-81
PubMed
医中誌リンクサービス
13)Zhang L, Lai E, Teodoro T, et al. GRP78, but not protein-disulfide isomerase, partially reverses hyperglycemia-induced inhibition of insulin synthesis and secretion in pancreatic {beta}-cells. J Biol Chem. 2009; 284: 5289-98
PubMed
医中誌リンクサービス
14)Zhang W, Feng D, Li Y, et al. PERK EIF2AK3 control of pancreatic beta cell differentiation and proliferation is required for postnatal glucose homeostasis. Cell Metab. 2006; 4: 491-7
PubMed CrossRef
医中誌リンクサービス
15)Gupta S, McGrath B, Cavener DR. PERK regulates the proliferation and development of insulin-secreting beta-cell tumors in the endocrine pancreas of mice. PLoS One. 2009; 4: e8008
CrossRef
医中誌リンクサービス
16)Lipson KL, Ghosh R, Urano F. The role of IRE1alpha in the degradation of insulin mRNA in pancreatic beta-cells. PLoS One. 2008; 3: e1648
CrossRef
医中誌リンクサービス
17)Huang CJ, Lin CY, Haataja L, et al. High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated beta-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes. Diabetes. 2007; 56: 2016-27
PubMed CrossRef
医中誌リンクサービス
18)Bachar E, Ariav Y, Ketzinel-Gilad M, et al. Glucose amplifies fatty acid-induced endoplasmic reticulum stress in pancreatic beta-cells via activation of mTORC1. PLoS One. 2009; 4: e4954
CrossRef
医中誌リンクサービス
19)Back SH, Scheuner D, Han J, et al. Translation attenuation through eIF2alpha phosphorylation prevents oxidative stress and maintains the differentiated state in beta cells. Cell Metab. 2009; 10: 13-26
PubMed CrossRef
医中誌リンクサービス
20)Newsholme P, Haber EP, Hirabara SM, et al. Diabetes associated cell stress and dysfunction: role of mitochondrial and non-mitochondrial ROS production and activity. J Physiol. 2007; 583: 9-24
PubMed CrossRef
医中誌リンクサービス
21)Thomas HE, McKenzie MD, Angstetra E, et al. Beta cell apoptosis in diabetes. Apoptosis. 2009; 14: 1389-404
PubMed CrossRef
医中誌リンクサービス
22)Tang C, Han P, Oprescu AI, et al. Evidence for a role of superoxide generation in glucose-induced beta-cell dysfunction in vivo. Diabetes. 2007; 56: 2722-31
PubMed CrossRef
医中誌リンクサービス
23)Santos CX, Tanaka LY, Wosniak J, et al. Mechanisms and implications of reactive oxygen species generation during the unfolded protein response: roles of endoplasmic reticulum oxidoreductases, mitochondrial electron transport, and NADPH oxidase. Antioxid Redox Signal. 2009; 11: 2409-27
医中誌リンクサービス
24)Bachar E, Ariav Y, Cerasi E, et al. Neuronal nitric oxide synthase protects the pancreatic beta cell from glucolipotoxicity-induced endoplasmic reticulum stress and apoptosis. Diabetologia. 2010; 53: 2177-87
PubMed CrossRef
医中誌リンクサービス
25)Martens GA, Cai Y, Hinke S, et al. Glucose suppresses superoxide generation in metaboli-cally responsive pancreatic beta cells. J Biol Chem. 2005; 280: 20389-96
PubMed CrossRef
医中誌リンクサービス
26)Terauchi Y, Sakura H, Yasuda K, et al. Pancreatic beta-cell-specific targeted disruption of glucokinase gene. Diabetes mellitus due to defective insulin secretion to glucose. J Biol Chem. 1995; 270: 30253-6
PubMed CrossRef
医中誌リンクサービス
27)Terauchi Y, Takamoto I, Kubota N, et al. Glucokinase and IRS-2 are required for compensatory beta cell hyperplasia in response to high-fat diet-induced insulin resistance. J Clin Invest. 2007; 117: 246-57
PubMed CrossRef
医中誌リンクサービス
28)Demozay D, Tsunekawa S, Briaud I, et al. Specific glucose-induced control of insulin receptor substrate-2 expression is mediated via Ca2+-dependent calcineurin/NFAT signaling in primary pancreatic islet beta-cells. Diabetes. 2011; 60: 2892-902
PubMed CrossRef
医中誌リンクサービス
29)Nakamura A, Terauchi Y, Ohyama S, et al. Impact of small-molecule glucokinase activator on glucose metabolism and beta-cell mass. Endocrinology. 2009; 150: 1147-54
PubMed
医中誌リンクサービス
30)Salpeter SJ, Klein AM, Huangfu D, et al. Glucose and aging control the quiescence period that follows pancreatic beta cell replication. Development. 2010; 137: 3205-13
医中誌リンクサービス
31)Nakamura A, Togashi Y, Orime K, et al. Control of beta cell function and proliferation in mice stimulated by small-molecule glucokinase activator under various conditions. Diabetologia. 2012; 55: 1745-54
PubMed CrossRef
医中誌リンクサービス
32)Shirakawa J, Amo K, Ohminami H, et al. Protective effects of dipeptidyl peptidase-4 (DPP-4) inhibitor against increased beta cell apoptosis induced by dietary sucrose and linoleic acid in mice with diabetes. J Biol Chem. 2011; 286: 25467-76
PubMed CrossRef
医中誌リンクサービス
33)Shirakawa J, Fujii H, Ohnuma K, et al. Diet-induced adipose tissue inflammation and liver steatosis are prevented by DPP-4 inhibition in diabetic mice. Diabetes. 2011; 60: 1246-57
PubMed CrossRef
医中誌リンクサービス
34)Porat S, Weinberg-Corem N, Tornovsky-Babaey S, et al. Control of pancreatic beta cell regene-ration by glucose metabolism. Cell Metab. 2011; 13: 440-9
PubMed CrossRef
医中誌リンクサービス
35)Danial NN, Walensky LD, Zhang CY, et al. Dual role of proapoptotic BAD in insulin secretion and beta cell survival. Nat Med. 2008; 14: 144-53
PubMed CrossRef
医中誌リンクサービス
36)Danial NN, Gramm CF, Scorrano L, et al. BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis. Nature. 2003; 424: 952-6
PubMed
医中誌リンクサービス
37)Sachdeva MM, Claiborn KC, Khoo C, et al. Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress. Proc Natl Acad Sci U S A. 2009; 106: 19090-5
PubMed CrossRef
医中誌リンクサービス
38)Srinivasan S, Ohsugi M, Liu Z, et al. Endoplasmic reticulum stress-induced apoptosis is partly mediated by reduced insulin signaling through phosphatidylinositol 3-kinase/Akt and increased glycogen synthase kinase-3beta in mouse insulinoma cells. Diabetes. 2005; 54: 968-75
PubMed CrossRef
医中誌リンクサービス
39)Yusta B, Baggio LL, Estall JL, et al. GLP-1 receptor activation improves beta cell function and survival following induction of endoplasmic reticulum stress. Cell Metab. 2006; 4: 391-406
PubMed CrossRef
医中誌リンクサービス
40)Cunha DA, Ladriere L, Ortis F, et al. Glucagon-like peptide-1 agonists protect pancreatic beta-cells from lipotoxic endoplasmic reticulum stress through upregulation of BiP and JunB. Diabetes. 2009; 58: 2851-62
PubMed CrossRef
医中誌リンクサービス
41)Shirakawa J, Tanami R, Togashi Y, et al. Effects of liraglutide on beta-cell-specific glucokinase-deficient neonatal mice. Endocrinology. 2012; 153: 3066-75
PubMed CrossRef
医中誌リンクサービス
42)Kooptiwut S, Kebede M, Zraika S, et al. High glucose-induced impairment in insulin secretion is associated with reduction in islet glucokinase in a mouse model of susceptibility to islet dysfunction. J Mol Endocrinol. 2005; 35: 39-48
PubMed CrossRef
医中誌リンクサービス
43)Kim WH, Lee JW, Suh YH, et al. Exposure to chronic high glucose induces beta-cell apoptosis through decreased interaction of glucokinase with mitochondria: downregulation of gluco-kinase in pancreatic beta-cells. Diabetes. 2005; 54: 2602-11
PubMed CrossRef
医中誌リンクサービス
44)Lee JW, Kim WH, Lim JH, et al. Mitochondrial dysfunction: glucokinase downregulation lowers interaction of glucokinase with mitochondria, resulting in apoptosis of pancreatic beta-cells. Cell Signal. 2009; 21: 69-78
PubMed CrossRef
医中誌リンクサービス
45)Joe MK, Lee HJ, Suh YH, et al. Crucial roles of neuronatin in insulin secretion and high glucose-induced apoptosis in pancreatic beta-cells. Cell Signal. 2008; 20: 907-15
PubMed CrossRef
医中誌リンクサービス
46)Wei P, Shi M, Barnum S, et al. Effects of glucokinase activators GKA50 and LY2121260 on proliferation and apoptosis in pancreatic INS-1 beta cells. Diabetologia. 2009; 52: 2142-50
PubMed CrossRef
医中誌リンクサービス
47)Futamura M, Yao J, Li X, et al. Chronic treat-ment with a glucokinase activator delays the onset of hyperglycaemia and preserves beta cell mass in the Zucker diabetic fatty rat. Diabetologia. 2012; 55: 1071-80
PubMed CrossRef
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