|
1）Kinsella KG. Changes in life expectancy 1900-1990. Am J Clin Nutr. 1992; 55: 1196S-202S
|
|
|
|
2）Lee R. The outlook for population growth. Science. 2011; 333: 569-73
|
|
|
|
|
|
3）Ohtani N, Takahashi A, Mann DJ, et al. Cellular senescence: a double-edged sword in the fight against cancer. Exp Dermatol. 2002; 21: S1-4
|
|
|
|
|
|
4）Kuilman T, Michaloglou C, Mooi WJ, et al. The essence of senescence. Genes Dev. 2010; 24: 2463-79
|
|
|
|
|
5）Herbig U, Sedivy JM. Cellular senescence in aging primates. Science. 2006; 311: 1257
|
|
|
|
|
|
6）Hara E, Smith R, Parry D, et al. Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence. Mol Cell Biol. 1996; 16: 859-67
|
|
|
|
|
|
7）Ohtani N, Zebedee Z, Huot TJ, et al. Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence. Nature. 2001; 409: 1067-70
|
|
|
|
|
|
8）Takahashi A, Ohtani N, Yamakoshi K, et al. Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence. Nat Cell Biol. 2006; 8: 1291-7
|
|
|
|
|
|
9）Yamakoshi K, Takahashi A, Hirota F, et al. Real-time in vivo imaging of p16Ink4a reveals cross talk with p53. J Cell Biol. 2009; 186: 393-407
|
|
|
|
|
|
10）Campisi J. Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell. 2005; 120: 513-22
|
|
|
|
|
|
11）Rodier F, Campisi J. Four faces of cellular senescence. J Cell Biol. 2011; 192: 547-56
|
|
|
|
|
|
12）Sparmann A, Bar-Sagi D. Ras-induced interleukin-8 expression plays a critical role in tumor growth and angiogenesis. Cancer Cell. 2004; 6: 447-58
|
|
|
|
|
|
13）Ancrile B, Lim KH, Counter CM. Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis. Genes Dev. 2007; 21: 1714-9
|
|
|
|
|
|
14）Jackson JG, Pant V, Li Q, et al. p53-mediated senescence impairs the apoptotic response to chemotherapy and clinical outcome in breast cancer. Cancer Cell. 2012; 21: 793-806
|
|
|
|
|
|
15）Acosta JC, O’Loghlen A, Banito A, et al. Chemokine signaling via the CXCR2 receptor reinforces senescence. Cell. 2008; 133: 1006-18
|
|
|
|
|
|
16）Kuilman T, Michaloglou C, Vredeveld LC, et al. Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network. Cell. 2008; 133: 1019-31
|
|
|
|
|
|
17）d’Adda di Fagagna F. Living on a break: cellular senescence as a DNA-damage response. Nat Rev Cancer. 2008; 8: 512-22
|
|
|
|
|
|
18）Rodier F, Coppe JP, Patil CK, et al. Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion. Nat Cell Biol. 2009; 11: 973-9
|
|
|
|
|
|
19）Takahashi A, Imai Y, Yamakoshi K, et al. DNA damage signaling triggers degradation of histone methyltransferases through APC/CCdh1 in senescent cells. Mol Cell. 2012; 45: 123-31
|
|
|
|
|
|
20）Estève PO, Chin HG, Smallwood A, et al. Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication. Genes Dev. 2006; 20: 3089-103
|
|
|
|
|
|
21）Levy D, Kuo AJ, Chang Y, et al. Lysine methylation of the NF-kappaB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-kappaB signaling. Nat Immunol. 2011; 12: 29-36
|
|
|
|
|
|
22）Pless O, Kowenz-Leutz E, Knoblich M, et al. G9a-mediated lysine methylation alters the function of CCAAT/enhancer-binding protein-beta. J Biol Chem. 2008; 283: 26357-63
|
|
|
|
|