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2)Forestier N, Zeuzem S. Telaprevir for the treat-ment of hepatitis C. Expert Opin Pharmacother. 2012; 13(4): 593-606
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4)Kodama T, Takehara T, Hikita H, et al. Thrombocytopenia exacerbates cholestasis-induced liver fibrosis in mice. Gastroenterology. 2010; 138(7): 2487-98, 2498. e1-7
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6)Friedman SL. Mechanisms of hepatic fibro-genesis. Gastroenterology. 2008; 134(6): 1655-69
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7)Gabele E, Brenner DA, Rippe RA. Liver fibrosis: signals leading to the amplification of the fibrogenic hepatic stellate cell. Front Biosci. 2003; 8: d69-77
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8)小玉尚宏, 竹原徹郎. 【血小板-beyond clotting】 肝線維化における血小板の役割. 日本血栓止血学会誌. 2011; 22(3): 71-76
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9)Ikeda N, Murata S, Maruyama T, et al. Platelet-derived adenosine 5-triphosphate suppresses activation of human hepatic stellate cell: In vitro study. Hepatol Res. 2012; 42(1): 91-102
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10)Zaldivar MM, Pauels K, von Hundelshausen P, et al. CXC chemokine ligand 4 (Cxcl4) is a platelet-derived mediator of experimental liver fibrosis. Hepatology. 2010; 51(4): 1345-53
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11)Kodama T, Takehara T, Hikita H, et al. BH3-only activator proteins, Bid and Bim, are dispensable for Bak/Bax-dependent thrombocyte apoptosis induced by Bcl-xL deficiency: Molecular requisites for the mitochondrial pathway to apoptosis in platelets. J Biol Chem. 2011; 286: 13905-13
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12)Watanabe M, Murata S, Hashimoto I, et al. Platelets contribute to the reduction of liver fibrosis in mice. J Gastroenterol Hepatol. 2009; 24(1): 78-89
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13)Murata S, Hashimoto I, Nakano Y, et al. Single administration of thrombopoietin prevents progression of liver fibrosis and promotes liver regeneration after partial hepatectomy in cirrhotic rats. Ann Surg. 2008; 248(5): 821-8
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14)Lee CM, Leung TK, Wang HJ, et al. Evaluation of the effect of partial splenic embolization on platelet values for liver cirrhosis patients with thrombocytopenia. World J Gastroenterol. 2007; 13(4): 619-22
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15)Murata K, Ito K, Yoneda K, et al. Splenectomy improves liver function in patients with liver cirrhosis. Hepatogastroenterology. 2008; 55(85): 1407-11
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16)Liu Q, Ma K, Song Y, et al. Two-year follow-up of splenic radiofrequency ablation in patients with cirrhotic hypersplenism: does increased hepatic arterial flow induce liver regeneration? Surgery. 2008; 143(4): 509-18
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17)Lesurtel M, Graf R, Aleil B, et al. Platelet-derived serotonin mediates liver regeneration. Science. 2006; 312(5770): 104-7
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18)Murata S, Ohkohchi N, Matsuo R, et al. Platelets promote liver regeneration in early period after hepatectomy in mice. World J Surg. 2007; 31(4): 808-16
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19)Matsuo R, Ohkohchi N, Murata S, et al. Platelets strongly induce hepatocyte proliferation with IGF-1 and HGF in vitro. J Surg Res. 2008; 145(2): 279-86
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20)Iannacone M, Sitia G, Isogawa M, et al. Platelets mediate cytotoxic T lymphocyte-induced liver damage. Nat Med. 2005; 11(11): 1167-9
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21)Laschke MW, Dold S, Menger MD, et al. Platelet-dependent accumulation of leukocytes in sinu-soids mediates hepatocellular damage in bile duct ligation-induced cholestasis. Br J Pharmacol. 2008; 153(1): 148-56
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22)Lang PA, Contaldo C, Georgiev P, et al. Aggravation of viral hepatitis by platelet-derived serotonin. Nat Med. 2008; 14(7): 756-61
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24)de Boer MT, Christensen MC, Asmussen M, et al. The impact of intraoperative transfusion of platelets and red blood cells on survival after liver transplantation. Anesth Analg. 2008; 106(1): 32-44, table of contents
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