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1)Vicente C, Conchillo A, Garcia-Sanchez MA, et al. The role of the GATA2 transcription factor in normal and malignant hematopoiesis. Crit Rev Oncol Hematol. 2012; 82(1): 1-17
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2)Vinh DC, Patel SY, Uzel G, et al. Autosomal dominant and sporadic monocytopenia with susceptibility to mycobacteria, fungi, papillo-maviruses, and myelodysplasia. Blood. 2010; 115(8): 1519-29
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3)Bigley V, Haniffa M, Doulatov S, et al. The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency. J Exp Med. 2011; 208(2): 227-34
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4)Hsu AP, Sampaio EP, Khan J, et al. Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndrome. Blood. 2011; 118(10): 2653-5
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5)Dickinson RE, Griffin H, Bigley V, et al. Exome sequencing identifies GATA-2 mutation as the cause of dendritic cell, monocyte, B and NK lymphoid deficiency. Blood. 2011; 118(10): 2656-8
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6)Hahn CN, Chong CE, Carmichael CL, et al. Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia. Nat Genet. 2011; 43(10): 1012-7
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7)Ostergaard P, Simpson MA, Connell FC, et al. Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia(Emberger syndrome). Nat Genet. 2011; 43(10): 929-31
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8)Bresnick EH, Katsumura KR, Lee HY, et al. Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies. Nucleic Acids Res. 2012; 40(13): 5819-31
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9)Tsai FY, Keller G, Kuo FC, et al. An early haematopoietic defect in mice lacking the transcription factor GATA-2. Nature. 1994; 371(6494): 221-6
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10)Tsai FY, Orkin SH. Transcription factor GATA-2 is required for proliferation/survival of early hematopoietic cells and mast cell formation, but not for erythroid and myeloid terminal differen-tiation. Blood. 1997; 89(10): 3636-43
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11)Rodrigues NP, Boyd AS, Fugazza C, et al. GATA-2 regulates granulocyte-macrophage progenitor cell function. Blood. 2008; 112(13): 4862-73
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12)Rodrigues NP, Janzen V, Forkert R, et al. Haploinsufficiency of GATA-2 perturbs adult hematopoietic stem-cell homeostasis. Blood. 2005; 106(2): 477-84
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13)Persons DA, Allay JA, Allay ER, et al. Enforced expression of the GATA-2 transcription factor blocks normal hematopoiesis. Blood. 1999; 93(2): 488-99
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14)Ishida H, Imai K, Honma K, et al. GATA-2 anomaly and clinical phenotype of a sporadic case of lymphedema, dendritic cell, monocyte, B- and NK-cell(DCML) deficiency, and myelodys-plasia. Eur J Pediatr. 2012; 171(8): 1273-6
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15)Bigley V, Collin M. Dendritic cell, monocyte, B and NK lymphoid deficiency defines the lost lineages of a new GATA-2 dependent myelodys-plastic syndrome. Haematologica. 2011; 96(8): 1081-3
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16)Calvo KR, Vinh DC, Maric I, et al. Myelodysplasia in autosomal dominant and sporadic mono-cytopenia immunodeficiency syndrome: diagnostic features and clinical implications. Haematologica. 2011; 96(8): 1221-5
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17)Kazenwadel J, Secker GA, Liu YJ, et al. Loss-of-function germline GATA2 mutations in patients with MDS/AML or MonoMAC syndrome and primary lymphedema reveal a key role for GATA2 in the lymphatic vasculature. Blood. 2012; 119(5): 1283-91
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18)Bodor C, Renneville A, Smith M, et al. Germ-line GATA2 p. THR354MET mutation in familial myelodysplastic syndrome with acquired monosomy 7 and ASXL1 mutation demonstrating rapid onset and poor survival. Haematologica. 2012; 97(6): 890-4
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19)Fadilah SA, Cheong SK, Roslan H, et al. GATA-1 and GATA-2 gene expression is related to the severity of dysplasia in myelodysplastic syndrome. Leukemia. 2002; 16(8): 1563-5
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20)Lahortiga I, Vazquez I, Agirre X, et al. Molecular heterogeneity in AML/MDS patients with 3q21q26 rearrangements. Genes Chromosomes Cancer. 2004; 40(3): 179-89
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21)Bullinger L, Dohner K, Bair E, et al. Use of gene-expression profiling to identify prognostic subclasses in adult acute myeloid leukemia. N Engl J Med. 2004; 350(16): 1605-16
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22)Vicente C, Vazquez I, Conchillo A, et al. Overexpression of GATA2 predicts an adverse prognosis for patients with acute myeloid leukemia and it is associated with distinct molecular abnormalities. Leukemia. 2012; 26(3): 550-4
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23)Luesink M, Hollink IH, van der Velden VH, et al. High GATA2 expression is a poor prognostic marker in pediatric acute myeloid leukemia. Blood. 2012; 120(10): 2064-75
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24)Zhang SJ, Ma LY, Huang QH, et al. Gain-of-function mutation of GATA-2 in acute myeloid transformation of chronic myeloid leukemia. Proc Natl Acad Sci U S A. 2008; 105(6): 2076-81
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25)Zhang SJ, Shi JY, Li JY. GATA-2 L359 V mutation is exclusively associated with CML progression but not other hematological malignancies and GATA-2 P250A is a novel single nucleotide polymorphism. Leuk Res. 2009; 33(8): 1141-3
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26)Greif PA, Dufour A, Konstandin NP, et al. GATA2 zinc finger 1 mutations associated with biallelic CEBPA mutations define a unique genetic entity of acute myeloid leukemia. Blood. 2012; 120(2): 395-403
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27)Fasan A, Eder C, Haferlach C, et al. GATA2 mutations are frequent in intermediate-risk karyotype AML with biallelic CEBPA mutations and are associated with favorable prognosis. Leukemi: 2012. 174. [Epub ahead of print]
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28)Tong Q, Tsai J, Tan G, et al. Interaction between GATA and the C/EBP family of transcription factors is critical in GATA-mediated suppression of adipocyte differentiation. Mol Cell Biol. 2005; 25(2): 706-15
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29)Yan XJ, Xu J, Gu ZH, et al. Exome sequencing identifies somatic mutations of DNA methyl-transferase gene DNMT3A in acute monocytic leukemia. Nat Genet. 2011; 43(4): 309-15
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30)Kumar MS, Hancock DC, Molina-Arcas M, et al. The GATA2 transcriptional network is requisite for RAS oncogene-driven non-small cell lung cancer. Cell. 2012; 149(3): 642-55
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31)Migliaccio AR, Bieker JJ. GATA2 finds its macrophage niche. Blood. 2011; 118(10): 2647-9
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