|
1）Paragas N, Qiu A, Zhang Q, et al. The Ngal reporter mouse detects the response of the kidney to injury in real time. Nat Med. 2011; 17: 216-22
|
|
|
|
2）Sola A, Weigert A, Jung M, et al. Sphingosine-1-phosphate signalling induces the production of Lcn-2 by macrophages to promote kidney regeneration. J Pathol. 2011; 225: 597-608
|
|
|
|
|
|
3）Viau A, El Karoui K, Laouari D, et al. Lipocalin 2 is essential for chronic kidney disease progression in mice and humans. J Clin Invest. 2010; 120: 4065-76
|
|
|
|
|
|
4）Law IK, Xu A, Lam KS, et al. Lipocalin-2 deficiency attenuates insulin resistance associated with aging and obesity. Diabetes. 2010; 59: 872-82
|
|
|
|
|
|
5）Jun LS, Siddall CP, Rosen ED. A minor role for lipocalin 2 in high-fat diet-induced glucose intolerance. Am J Physiol Endocrinol Metab. 2011; 301: E825-35
|
|
|
|
|
|
6）Guo H, Jin D, Zhang Y, et al. Lipocalin-2 deficiency impairs thermogenesis and potentiates diet-induced insulin resistance in mice. Diabetes. 2010; 59: 1376-85
|
|
|
|
|
|
7）Bao G, Clifton M, Hoette TM, et al. Iron traffics in circulation bound to a siderocalin (Ngal)-catechol complex. Nat Chem Biol. 2010; 6: 602-9
|
|
|
|
|
|
8）Mori K, Yang J, Barasch J. Ureteric bud controls multiple steps in the conversion of mesenchyme to epithelia. Semin Cell Dev Biol. 2003; 14: 209-16
|
|
|
|
|
|
9）Barasch J, Yang J, Ware CB, et al. Mesenchymal to epithelial conversion in rat metanephros is induced by LIF. Cell. 1999; 99: 377-86
|
|
|
|
|
|
10）Yang J, Goetz D, Li JY, et al. An iron delivery pathway mediated by a lipocalin. Mol Cell. 2002; 10: 1045-56
|
|
|
|
|
|
11）Goetz DH, Holmes MA, Borregaard N, et al. The neutrophil lipocalin NGAL is a bacteriostatic agent that interferes with siderophore-mediated iron acquisition. Mol Cell. 2002; 10: 1033-43
|
|
|
|
|
|
12）Li JY, Ram G, Gast K, et al. Detection of intracellular iron by its regulatory effect. Am J Physiol Cell Physiol. 2004; 287: C1547-59
|
|
|
|
|
|
13）Mori K, Lee HT, Mukoyama M, et al. Endocytic delivery of lipocalin-siderophore-iron complex rescues the kidney from ischemia-reperfusion injury. J Clin Invest. 2005; 115: 610-21
|
|
|
|
|
|
14）森 潔，向山政志，中尾一和．siderophore結合蛋白の生物学～分化誘導，組織障害，癌，感染，造血の新しい接点～．臨床血液. 2009; 50: 519-26
|
|
|
|
|
15）森 潔, 向山政志, 中尾一和. 微生物の鉄捕捉分子と生体の防御機構. 日本内科学会雑誌. 2010; 99: 1188-93
|
|
|
|
|
|
16）Schmidt-Ott KM, Mori K, Li JY, et al. Dual action of neutrophil gelatinase-associated lipocalin. J Am Soc Nephrol. 2007; 18: 407-13
|
|
|
|
|
|
17）Supavekin S, Zhang W, Kucherlapati R, et al. Differential gene expression following early renal ischemia/reperfusion. Kidney Int. 2003; 63: 1714-24
|
|
|
|
|
|
18）Mishra J, Dent C, Tarabishi R, et al. Neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute renal injury after cardiac surgery. Lancet. 2005; 365: 1231-8
|
|
|
|
|
|
19）Mori K, Nakao K. Neutrophil gelatinase-associated lipocalin as the real-time indicator of active kidney damage. Kidney Int. 2007; 71: 967-70
|
|
|
|
|
|
20）森 潔, 向山政志, 桒原孝成, 他. ＣＫＤにおける新規バイオマーカーNgalの意義. 日本臨牀. 2009; 67: 1233-41
|
|
|
|
|
|
21）Nickolas TL, O’Rourke MJ, Yan J, et al. Sensitivity and specificity of a single emergency department measurement of urinary neutrophil gelatinase-associated lipocalin for diagnosing acute kidney injury. Ann Intern Med. 2008; 148: 810-19
|
|
|
|
|
|
22）Bolignano D, Lacquaniti A, Coppolino G, et al. Neutrophil gelatinase-associated lipocalin (NGAL) and progression of chronic kidney disease. Clin J Am Soc Nephrol. 2009; 4: 337-44
|
|
|
|
|
|
23）Kuwabara T, Mori K, Mukoyama M, et al. Urinary neutrophil gelatinase-associated lipocalin levels reflect damage to glomeruli, proximal and distal nephrons. Kidney Int. 2009; 75: 285-94
|
|
|
|
|
|
24）Cowland JB, Muta T, Borregaard N. IL-1beta-specific up-regulation of neutrophil gelatinase-associated lipocalin is controlled by IkappaB-zeta. J Immunol. 2006; 176: 5559-66
|
|
|
|
|
|
25）Mishra J, Mori K, Ma Q, et al. Amelioration of ischemic acute renal injury by neutrophil gelatinase-associated lipocalin. J Am Soc Nephrol. 2004; 15: 3073-82
|
|
|
|
|
|
26）Berger T, Togawa A, Duncan GS, et al. Lipocalin 2-deficient mice exhibit increased sensitivity to Escherichia coli infection but not to ischemia-reperfusion injury. Proc Natl Acad Sci U S A. 2006; 103: 1834-9
|
|
|
|
|
|
27）Flo TH, Smith KD, Sato S, et al. Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron. Nature. 2004; 432: 917-21
|
|
|
|
|
|
28）Barasch J, Mori K. Cell biology: iron thievery. Nature. 2004; 432: 811-3
|
|
|
|
|
|
29）Martineau AR, Newton SM, Wilkinson KA, et al. Neutrophil-mediated innate immune resistance to mycobacteria. J Clin Invest. 2007; 117: 1988-94
|
|
|
|
|
|
30）Aujla SJ, Chan YR, Zheng M, et al. IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia. Nat Med. 2008; 14: 275-81
|
|
|
|
|
|
31）Fluckinger M, Haas H, Merschak P, et al. Human tear lipocalin exhibits antimicrobial activity by scavenging microbial siderophores. Antimicrob Agents Chemother. 2004; 48: 3367-72
|
|
|
|
|
|
32）Kjeldsen L, Johnsen AH, Sengelov H, et al. Isolation and primary structure of NGAL, a novel protein associated with human neutrophil gelatinase. J Biol Chem. 1993; 268: 10425-32
|
|
|
|
|
|
33）Borregaard N, Cowland JB. Granules of the human neutrophilic polymorphonuclear leukocyte. Blood. 1997; 89: 3503-21
|
|
|
|
|
|
34）Miharada K, Hiroyama T, Sudo K, et al. Lipocalin 2 functions as a negative regulator of red blood cell production in an autocrine fashion. FASEB J. 2005; 19: 1881-83
|
|
|
|
|
|
35）Miharada K, Hiroyama T, Sudo K, et al. Lipocalin 2-mediated growth suppression is evident in human erythroid and monocyte/macrophage lineage cells. J Cell Physiol. 2008; 215: 526-37
|
|
|
|
|
|
36）Devireddy LR, Teodoro JG, Richard FA, et al. Induction of apoptosis by a secreted lipocalin that is transcriptionally regulated by IL-3 deprivation. Science. 2001; 293: 829-34
|
|
|
|
|
|
37）Devireddy LR, Gazin C, Zhu X, et al. A cell-surface receptor for lipocalin 24p3 selectively mediates apoptosis and iron uptake. Cell. 2005; 123: 1293-305
|
|
|
|
|
|
38）Lee S, Lee J, Mori K, et al. A dual role of lipocalin 2 in the apoptosis and deramification of activated microglia. J Immunol. 2007; 179: 3231-41
|
|
|
|
|
|
39）Lee S, Park JY, Mori K, et al. Lipocalin-2 is an autocrine mediator of reactive astrocytosis. J Neurosci. 2009; 29: 234-49
|
|
|
|
|
|
40）Lee S, Lee WH, Lee MS, et al. Regulation by lipocalin-2 of neuronal cell death, migration, and morphology. J Neurosci Res. 2012; 90: 540-50
|
|
|
|
|
|
41）Hanai J, Mammoto T, Seth P, et al. Lipocalin 2 diminishes invasiveness and metastasis of Ras-transformed cells. J Biol Chem. 2005; 280: 13641-7
|
|
|
|
|
|
42）Bolignano D, Donato V, Lacquaniti A, et al. Neutrophil gelatinase-associated lipocalin (NGAL) in human neoplasias: a new protein enters the scene. Cancer Lett. 2010; 288: 10-6
|
|
|
|
|
|
43）Yan QW, Yang Q, Mody N, et al. The adipokine lipocalin 2 is regulated by obesity and promotes insulin resistance. Diabetes. 2007; 56: 2533-40
|
|
|
|
|
|
44）Wang Y, Lam KS, Kraegen EW, et al. Lipocalin-2 is an inflammatory marker closely associated with obesity, insulin resistance, and hyperglycemia in humans. Clin Chem. 2007; 53: 34-41
|
|
|
|
|