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15) Reni M, Ferreri AJ, Guha-Thakurta N, et al. Clinical relevance of consolidation radiotherapy and other main therapeutic issues in primary central nervous system lymphomas treated with upfront high-dose methotrexate. Int J Radiat Oncol Biol Phys. 2001; 51: 419-25
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18) Pels H, Schmidt-Wolf IG, Glasmacher A, et al. Primary central nervous system lymphoma: results of a pilot and phase II study of systemic and intraventricular chemotherapy with deferred radiotherapy. J Clin Oncol. 2003; 21: 4489-95
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19) Pels H, Juergens A, Glasmacher A, et al. Early relapses in primary CNS lymphoma after response to polychemotherapy without intra-ventricular treatment: results of a phase II study. J Neurooncol. 2009; 91: 299-305
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20) Angelov L, Doolittle ND, Kraemer DF, et al. Blood-brain barrier disruption and intra-arterial methotrexate-based therapy for newly diagnosed primary CNS lymphoma: a multi-institutional experience. J Clin Oncol. 2009; 27: 3503-9
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22) Omuro AM, Taillandier L, Chinot O, et al. C Temozolomide and methotrexate for primary central nervous system lymphoma in the elderly. J Neurooncol. 2007; 85: 207-11
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23) Reni M, Zaja F, Mason W, et al. Temozolomide as salvage treatment in primary brain lympho-mas. Br J Cancer. 2007; 96: 864-7
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28) Maza S, Kiewe P, Munz DL, et al. First report on a prospective trial with yttrium-90-labeled ibritumomab tiuxetan (Zevalin) in primary CNS lymphoma. Neuro Oncol. 2009; 11: 423-9
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29) Thiel E, Korfel A, Martus P, et al. High-dose methotrexate with or without whole brain radio-therapy for primary CNS lymphoma (G-PCNSL-SG-1): a phase 3, randomised, non-inferiority trial. Lancet Oncol. 2010; 11: 1036-47
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30) James L, Rubenstein, Jeffrey L, et al. Intensive chemotherapy and immunotherapy, without brain irradiation, in newly diagnosed patients with primary CNS Lymphoma: Results of CALGB 50202 Blood (ASH Annual Meeting Abstracts), Nov 2010; 116: 763
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31) Omuro A, Taillandier L, Chinot O, et al. ANOCEF Group (French Neuro-Oncology Association). Primary CNS lymphoma in patients younger than 60: can whole-brain radiotherapy be deferred? J Neurooncol. 2011; 104: 323-30
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34) Ferreri AJ, Verona C, Politi LS, et al. Consoli-dation radiotherapy in primary central nervous system lymphomas: impact on outcome of differ-ent fields and doses in patients in complete remission after upfront chemotherapy. Int J Radiat Oncol Biol Phys. 2011; 80: 169-75
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35) Correa DD, Maron L, Harder H, et al. Cognitive functions in primary central nervous system lymphoma: literature review and assessment guidelines. Ann Oncol. 2007; 18: 1145-51
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36) Soussain C, Hoang-Xuan K, Taillandier L, et al. Intensive chemotherapy followed by hemato-poietic stem-cell rescue for refractory and recur-rent primary CNS and intraocular lymphoma: Societe Francaise de Greffe de Moelle Osseuse-Therapie Cellulaire. J Clin Oncol. 2008; 26: 2512-8
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37) Illerhaus G, Marks R, Ihorst G, et al. High-dose chemotherapy with autologous stem-cell trans-plantation and hyperfractionated radiotherapy as first-line treatment of primary CNS lymphoma. J Clin Oncol. 2006; 24: 3865-70
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38) Illerhaus G, Muller F, Feuerhake F, et al. High-dose chemotherapy and autologous stem-cell transplantation without consolidating radiotherapy as first-line treatment for primary lymphoma of the central nervous system. Haematologica. 2008; 93: 147-8
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42) Ferreri AJ. How I treat primary CNS lymphoma. Blood. 2011; 118: 510-22
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43) Widemann BC, Balis FM, Kim A, et al. Glucar-pidase, leucovorin, and thymidine for high-dose methotrexate-induced renal dysfunction: clinical and pharmacologic factors affecting outcome. J Clin Oncol. 2010; 28: 3979-86
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44) Abrey LE, Yahalom J, DeAngelis LM. Treatment for primary CNS lymphoma: the next step. J Clin Oncol. 2000; 18: 3144-50
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45) OʼBrien P, Roos D, Pratt G, et al. Phase II multi-center study of brief single-agent methotrexate followed by irradiation in primary CNS lymphoma. J Clin Oncol. 2000; 18: 519-26
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46) Bessell EM, Lopez-Guillermo A, Villa S, et al. Importance of radiotherapy in the outcome of patients with primary CNS lymphoma: an analy-sis of the CHOD/BVAM regimen followed by two different radiotherapy treatments. J Clin Oncol. 2002; 20: 231-6
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47) Zhu JJ, Gerstner ER, Engler DA, et al. High-dose methotrexate for elderly patients with primary CNS lymphoma. Neuro Oncol. 2009; 11: 211-5
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