|
1) Calle EE, Rodriguez C, Walker-Thurmond K, et al. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U. S. adults. N Engl J Med. 2003; 348: 1625-38
|
|
|
|
2) Larsson SC, Permert J, Håkansson N, et al. Overall obesity, abdominal adiposity, diabetes and cigarette smoking in relation to the risk of pancreatic cancer in two Swedish population-based cohorts. Br J Cancer. 2005; 93: 1310-5
|
|
|
|
|
|
3) Li D, Morris JS, Liu J, et al. Body mass index and risk, age of onset, and survival in patients with pancreatic cancer. JAMA. 2009; 301: 2553-62
|
|
|
|
|
|
4) Lin Y, Kikuchi S, Tamakoshi A, et al. Obesity, physical activity and the risk of pancreatic cancer in a large Japanese cohort. Int J Cancer. 2007; 120: 2665-71
|
|
|
|
|
|
5) Everhart J, Wright D. Diabetes mellitus as a risk factor for pancreatic cancer. JAMA. 1995; 273: 1605-9
|
|
|
|
|
|
6) Huxley R, Ansary-Moghaddam A, Berrington de González A, et al. Type-II diabetes and pancreatic cancer: a meta-analysis of 36 studies. Br J Cancer. 2005; 92: 1076-83
|
|
|
|
|
|
7) Gapstur SM, Gann PH, Lowe W, et al. Abnormal glucose metabolism and pancreatic cancer mortality. JAMA. 2000; 283: 2552-8
|
|
|
|
|
|
8) Tilg H, Moschen AR. Adipocytokines: mediators linking adipose tissue, inflammation and immunity. Nat Rev Immunology. 2006; 6: 772-83
|
|
|
|
|
|
9) Calle EE, Kaaks R. Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms. Nat Rev Cancer. 2004; 4: 579-91
|
|
|
|
|
|
10) Butler AE, Galasso R, Matveyenko A, et al. Pancreatic duct replication is increased with obesity and type 2 diabetes in humans. Diabetologia. 2010; 53: 21-6
|
|
|
|
|
|
11) Li D, Yeung S-C J, Hassan MM, et al. Antidiabetic therapies affect risk of pancreatic cancer. Gastroenterology. 2009; 137: 482-8
|
|
|
|
|
|
12) Zakikhani M, Dowling R, Fantus IG, et al. Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells. Cancer Res. 2006; 66: 10269-73
|
|
|
|
|
|
13) Yang Y-X. Do diabetes drugs modify the risk of pancreatic cancer ？ Gastroenterology. 2009; 137: 412-5
|
|
|
|
|
|
14) Mathur A, Zyromski NJ, Pitt HA, et al. Pancreatic steatosis promotes dissemination and lethality of pancreatic cancer. J Am Coll Surg. 2009; 208: 989-96
|
|
|
|
|
|
15) Zyromski NJ, Mathur A, Pitt HA, et al. Obesity potentiates the growth and dissemination of pancreatic cancer. Surgery. 2009; 146: 258-63
|
|
|
|
|