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1) Widdicombe JH. Regulation of the depth and composition of airway surface liquid. J Anat. 2002; 201: 313–38
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2) King LS, Yasui M, Agre P. Aquaporins in health and disease. Mol Med Today. 2000; 6: 60-5
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3) Kozono D, Yasui M, King LS, et al. Aquaporin water channels: atomic structure molecular dynamics meet clinical medicine. J Clin Invest. 2002; 109: 1395-9
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4) Verkman AS. Role of aquaporins in lung liquid physiology. Respir Physiol Neurobiol. 2007; 159: 324-30
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5) Maeda S, Ito H, Tanaka K, et al. Localization of aquaporin water channels in the airway of the musk shrew (Suncus murinus) and the rat. J Vet Med Sci. 2005; 67: 975-84
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6) Qiao R, Yan W, Clavijo C, et al. Effects of KGF on alveolar epithelial cell transdifferentiation are mediated by JNK signaling. Am J Respir Cell Mol Biol. 2008; 38: 239-46
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7) Ma T, Fukuda N, Song Y, Matthay MA, et al. Lung fluid transport in aquaporin-5 knockout mice. J Clin Invest. 2000; 105: 93-100
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8) Song Y, Verkman AS. Aquaporin-5 dependent fluid secretion in airway submucosal glands. J Biol Chem. 2001; 276: 41288-92
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9) Ma T, Song Y, Gillespie A, et al. Defective secretion of saliva in transgenic mice lacking aquaporin-5 water channels. J Biol Chem. 1999; 274: 20071-4
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10) Song Y, Sonawane N, Verkman AS. Localization of aquaporin-5 in sweat glands and functional analysis using knockout mice. J Physiol. 2002; 541: 561-8
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11) Ma T, Fukuda N, Song Y, et al. Lung fluid transport in aquaporin-5 knockout mice. J Clin Invest. 2000; 105: 93-100
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12) Towne JE, Harrod KS, Krane CM, et al. Decreased expression of aquaporin (AQP)1 and AQP5 in mouse lung after acute viral infection. Am J Respir Cell Mol Biol. 2000; 22: 34-44
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13) Towne JE, Krane CM, Bachurski CJ, et al. Tumor necrosis factor-alpha inhibits aquaporin 5 expression in mouse lung epithelial cells. J Biol Chem. 2001; 276: 18657-64
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14) Ohinata A, Nagai K, Nomura J, et al. Lipopolysaccharide changes the subcellular distribution of aquaporin 5 and increases plasma membrane water permeability in mouse lung epithelial cells. Biochem Biophys Res Commun. 2005; 326: 521-6
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15) Krane CM, Deng B, Mutyam V, et al. Altered regulation of aquaporin gene expression in allergen and IL-13-induced mouse models of asthma. Cytokine. 2009; 46: 111-8
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16) Wang K, Feng YL, Wen FQ, et al. Decreased expression of human aquaporin-5 correlated with mucus overproduction in airways of chronic obstructive pulmonary disease. Acta Pharmacol Sin. 2007; 28: 1166-74
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17) Tsang KW, Leung JC, Tipoe GL, et al. Down-regulation of aquaporin 3 in bronchiectatic airways in vivo. Respir Med. 2003; 97: 59-64
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18) Horie I, Maeda M, Yokoyama S, et al. Tumor necrosis factor-alpha decreases aquaporin-3 expression in DJM-1 keratinocytes. Biochem Biophys Res Commun. 2009; 387: 564-8
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19) Hara-Chikuma M, Verkman AS. Roles of aquaporin-3 in the epidermis. J Invest Dermatol. 2008; 128: 2145-51
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20) Hirano Y, Okimoto N, Kadohira I, et al. Molecular mechanisms of how mercury inhibits water permeation through aquaporin-1: understanding by molecular dynamics simulation. Biophys J. 2010; 98: 1512-9
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21) Savage DF, Stroud RM. Structural basis of aquaporin inhibition by mercury. J Mol Biol. 2007; 368: 607-17
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22) Shahani N, Sawa A. Nitric oxide signaling and nitrosative stress in neurons: role for s-nitrosylation. Antioxid Redox Signal. 2011; 14: 1493-504
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23) Nagai K, Watanabe M, Seto M, et al. Nitric oxide decreases cell surface expression of aquaporin-5 and membrane water permeability in lung epithelial cells. Biochem Biophys Res Commun. 2007; 354: 579-84
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24) 礒濱洋一郎, 坂本唯真, 久恒昭哲, 他. 上気道と下気道のアクアポリン. 日本呼吸器学会雑誌. 2011; 49 suppl: 31
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