1) Royaux IE, Wall SM, Karniski LP, et al. Pendrin, encoded by the Pendred syndrome gene, resides in the apical region of renal intercalated cells and mediates bicarbonate secretion. Proc Natl Acad Sci U S A. 2001; 98: 4221-6
|
|
|
2) Frische S, Kwon TH, Frokiaer J, et al. Regulated expression of pendrin in rat kidney in response to chronic NH4Cl or NaHCO3 loading. Am J Physiol Renal Physiol. 2003; 284: F584-93
|
|
|
3) Muto S, Yasoshima K, Yoshitomi K, et al. Electrophysiological identification of alpha- and beta-intercalated cells and their distribution along the rabbit distal nephron segments. J Clin Invest. 1990; 86: 1829-39
|
|
|
4) McKinney TD, Burg MB. Bicarbonate transport by rabbit cortical collecting tubules. Effect of acid and alkali loads in vivo on transport in vitro. J Clin Invest. 1977; 60: 766-8
|
|
|
5) Schwartz GJ, Barasch J, Al-Awqati Q. Plasticity of functional epithelial polarity. Nature. 1985; 318: 368-71
|
|
|
6) Satlin LM, Schwartz GJ. Cellular remodeling of HCO3(-)-secreting cells in rabbit renal collecting duct in response to an acidic environment. J Cell Biol. 1989; 109: 1279-88
|
|
|
7) Emmons C, Kurtz I. Functional characterization of three intercalated cell subtypes in the rabbit outer cortical collecting duct. J Clin Invest. 1994; 93: 417-23
|
|
|
8) Hayashi M, Schuster VL, Stokes JB. Absence of transepithelial anion exchange by rabbit OMCD: evidence against reversal of cell polarity. Am J Physiol. 1988; 255(2 Pt 2): F220-8
|
|
|
9) Sabolic I, Brown D, Gluck SL, et al. Regulation of AE1 anion exchanger and H(+)-ATPase in rat cortex by acute metabolic acidosis and alkalosis. Kidney Int. 1997; 51: 125-37
|
|
|
10) Tsuruoka S, Schwartz GJ. Adaptation of rabbit cortical collecting duct HCO3- transport to metabolic acidosis in vitro. J Clin Invest. 1996; 97: 1076-84
|
|
|
11) Merot J, Giebisch G, Geibel J. Intracellular acidification induces Cl/HCO3 exchange activity in the basolateral membrane of beta-intercalated cells of the rabbit cortical collecting duct. J Membr Biol. 1997; 159: 253-62
|
|
|
12) Petrovic S, Wang Z, Ma L, et al. Regulation of the apical Cl-/HCO3- exchanger pendrin in rat cortical collecting duct in metabolic acidosis. Am J Physiol Renal Physiol. 2003; 284: F103-12
|
|
|
13) Purkerson JM, Tsuruoka S, Suter DZ, et al. Adaptation to metabolic acidosis and its recovery are associated with changes in anion exchanger distribution and expression in the cortical collecting duct. Kidney Int. 2010; 78: 993-1005
|
|
|
14) Schwartz JH, Alexander EA. Adaptation of intercalated cells along the collecting duct to systemic acid/base changes. Kidney Int. 2010; 78: 949-51
|
|
|
15) van Adelsberg J, Edwards JC, Takito J, et al. An induced extracellular matrix protein reverses the polarity of band 3 in intercalated epithelial cells. Cell. 1994; 76: 1053-61
|
|
|
16) Hikita C, Vijayakumar S, Takito J, et al. Induction of terminal differentiation in epithelial cells requires polymerization of hensin by galectin 3. J Cell Biol. 2000; 151: 1235-46
|
|
|
17) Al-Awqati Q. Terminal differentiation in epithelia: the role of integrins in hensin polymerization. Annu Rev Physiol. 2011; 73: 401-12
|
|
|
18) Takito J, Yan L, Ma J, et al. Hensin, the polarity reversal protein, is encoded by DMBT1, a gene frequently deleted in malignant gliomas. Am J Physiol. 1999; 277(2 Pt 2): F277-89
|
|
|
19) Gao X, Eladari D, Leviel F, et al. Deletion of hensin/DMBT1 blocks conversion of beta- to alpha-intercalated cells and induces distal renal tubular acidosis. Proc Natl Acad Sci U S A. 2010; 107: 21872-7
|
|
|
20) Schwartz G, Tsuruoka S, Vijayakumar S, et al. Acid incubation reverses the polarity of intercalated cell transporters, an effect mediated by hensin. J Clin Invest. 2002; 109: 89-99
|
|
|
21) Jaramillo-Juarez F, Rodriguez-Vazquez ML, Namorado MC, et al. Acidosis and weight loss are induced by cyclosporin A in uninephrectomized rats. Pediatr Nephrol. 2000; 14: 122-7
|
|
|
22) Fischer G, Aumuller T. Regulation of peptide bond cis/trans isomerization by enzyme catalysis and its implication in physiological processes. Rev Physiol Biochem Pharmacol. 2003; 148: 105-50
|
|
|
23) Peng H, Vijayakumar S, Schiene-Fischer C, et al. Secreted cyclophilin A, a peptidylprolyl cis-trans isomerase, mediates matrix assembly of hensin, a protein implicated in epithelial differentiation. J Biol Chem. 2009; 284: 6465-75
|
|
|
24) Watanabe S, Tsuruoka S, Vijayakumar S, et al. Cyclosporin A produces distal renal tubular acidosis by blocking peptidyl prolyl cis-trans isomerase activity of cyclophilin. Am J Physiol Renal Physiol. 2004; 7: 7
|
|
|
25) Ludwig MG, Vanek M, Guerini D, et al. Proton-sensing G-protein-coupled receptors. Nature. 2003; 425: 93-8
|
|
|
26) Radu CG, Nijagal A, McLaughlin J, et al. Differential proton sensitivity of related G protein-coupled receptors T cell death-associated gene 8 and G2A expressed in immune cells. Proc Natl Acad Sci U S A. 2005; 102: 1632-7
|
|
|
27) Frick KK, Krieger NS, Nehrke K, et al. Metabolic acidosis increases intracellular calcium in bone cells through activation of the proton receptor OGR1. J Bone Miner Res. 2009; 24: 305-13
|
|
|
28) Tobo M, Tomura H, Mogi C, et al. Previously postulated “ligand-independent" signaling of GPR4 is mediated through proton-sensing mechanisms. Cell Signal. 2007; 19: 1745-53
|
|
|
29) Sun X, Yang LV, Tiegs BC, et al. Deletion of the pH sensor GPR4 decreases renal acid excretion. J Am Soc Nephrol. 2010; 21: 1745-55
|
|
|
30) Mahadevan MS, Baird S, Bailly JE, et al. Isolation of a novel G protein-coupled receptor (GPR4) localized to chromosome 19q13. 3. Genomics. 1995; 30: 84-8
|
|
|
31) Yang LV, Radu CG, Roy M, et al. Vascular abnormalities in mice deficient for the G protein-coupled receptor GPR4 that functions as a pH sensor. Mol Cell Biol. 2007; 27: 1334-47
|
|
|
32) Codina J, Du W, Willingham M, et al. GPR4 may serve as a pH sensor to regulate the colonic H+, K+-ATPase (HKalpha2) in the renal medulla [Abstract]. J Am Soc Nephrol. 2008; 19: 40A
|
|
|