|
1) Schmieder RE, Hilgers KF, Schlaich MP, et al. Renin-angiotensin system and cardiovascular risk. Lancet. 2007; 369: 1208-19
|
|
|
|
2) Berl T. Renal protection by inhibition of the renin-angiotensin-aldosterone system. J Renin Angiotensin Aldosterone Syst. 2009; 10: 1-8
|
|
|
|
|
|
3) Bader M. Tissue renin-angiotensin-aldosterone systems: Targets for pharmacological therapy. Annu Rev Pharmacol Toxicol. 2010; 50: 439-65
|
|
|
|
|
|
4) Wühl E, Schaefer F. Managing kidney disease with blood-pressure control. Nat Rev Nephrol. 2011 (in press)
|
|
|
|
|
|
5) Kobori H, Nangaku M, Navar LG, et al. The intrarenal renin-angiotensin system: from physiology to the pathobiology of hypertension and kidney disease. Pharmacol Rev. 2007; 59: 251-87
|
|
|
|
|
|
6) Yosypiv IV. Renin-angiotensin system in ureteric bud branching morphogenesis: insights into the mechanisms. Pediatr Nephrol. 2011 (in press)
|
|
|
|
|
|
7) Anderson S, Rennke HG, Brenner BM. Therapeutic advantage of converting enzyme inhibitors in arresting progressive renal disease associated with systemic hypertension in the rat. J Clin Invest. 1986; 77: 1993-2000
|
|
|
|
|
|
8) Kagami S, Border WA, Miller DE, et al. Angiotensin II stimulates extracellular matrix protein synthesis through induction of transforming growth factor-beta expression in rat glomerular mesangial cells. J Clin Invest. 1994; 93: 2431-7
|
|
|
|
|
|
9) van der Meer IM, Cravedi P, Remuzzi G. The role of renin angiotensin system inhibition in kidney repair. Fibrogenesis Tissue Repair. 2010; 3: 1-11
|
|
|
|
|
|
10) Seikaly MG, Arant BS Jr, Seney FD Jr. Endogenous angiotensin concentrations in specific intrarenal fluid compartments of the rat. J Clin Invest. 1990; 86: 1352-7
|
|
|
|
|
|
11) Atiyeh BA, Arant BS Jr, Henrich WL, et al. In vitro production of angiotensin II by isolated glomeruli. Am J Physiol. 1995; 268: F266-72
|
|
|
|
|
|
12) Lai KN, Leung JC, Lai KB, et al. Gene expression of the renin-angiotensin system in human kidney. J Hypertens. 1998; 16: 91-102
|
|
|
|
|
|
13) Lee LK, Meyer TW, Pollock AS, et al Endothelial cell injury initiates glomerular sclerosis in the rat remnant kidney. J Clin Invest. 1995; 96: 953-64
|
|
|
|
|
|
14) Singh R, Singh AK, Leehey DJ. A novel mechanism for angiotensin II formation in streptozotocin-diabetic rat glomeruli. Am J Physiol Renal Physiol. 2005; 288: F1183-90
|
|
|
|
|
|
15) Leehey DJ, Singh AK, Bast JP, et al. Glomerular renin angiotensin system in streptozotocin diabetic and Zucker diabetic fatty rats. Transl Res. 2008; 151: 208-16
|
|
|
|
|
|
16) Kondo S, Shimizu M, Urushihara M, et al. Addition of the antioxidant probucol to angiotensin II type I receptor antagonist arrests progressive mesangioproliferative glomerulonephritis in the rat. J Am Soc Nephrol. 2006; 17: 783-94
|
|
|
|
|
|
17) Urushihara M, Takamatsu M, Shimizu M, et al. ERK5 activation enhances mesangial cell viability and collagen matrix accumulation in rat progressive glomerulonephritis. Am J Physiol Renal Physiol. 2010; 298: F167-76
|
|
|
|
|
|
18) Kinoshita A, Kondo S, Urushihara M, et al. Angiotensin II type I receptor blockade suppresses glomerular RAS activation, oxidative stress, and glomerular injury in crescentic glomerulonephritis. Transl Res. 2011(in press)
|
|
|
|
|
|
19) Takamatsu M, Urushihara M, Kondo S, et al. Glomerular angiotensinogen protein is enhanced in pediatric IgA nephropathy. Pediatr Nephrol. 2008; 23: 1257-67
|
|
|
|
|
|
20) Nishiyama A, Konishi Y, Ohashi N, et al. Urinary angiotensinogen reflects the activity of intrarenal renin-angiotensin system in patients with IgA nephropathy. Nephrol Dial Transplant. 2011; 26: 170-7
|
|
|
|
|
|
21) Yamamoto T, Nakagawa T, Suzuki H, et al. Urinary angiotensinogen as a marker of intrarenal angiotensin II activity associated with deterioration of renal function in patients with chronic kidney disease. J Am Soc Nephrol. 2007; 18: 1558-65
|
|
|
|
|
|
22) Urushihara M, Kondo S, Kagami S, et al. Urinary angiotensinogen accurately reflects intrarenal renin-angiotensin system activity. Am J Nephrol. 2010; 31: 318-25
|
|
|
|
|
|
23) Velez JC, Ryan KJ, Harbeson CE, et al. Angiotensin I is largely converted to angiotensin (1-7) and angiotensin (2-10) by isolated rat glomeruli. Hypertension. 2009; 53: 790-7
|
|
|
|
|
|
24) Velez JC, Janech MG, Arthur JM, et al. Cultured human glomerular endothelial cells display ACE-mediated angiotensin-II-generating capacity and limited angiotensin-II-degrading activity. Am Soc Nephrol Renal week(abstract). 2010; CD version
|
|
|
|
|