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3) Ando Y, Nakamura M, Araki S, et al. Transthyretin-related familial amyloidotic polyneuropathy. Arch Neurol. 2005; 62: 1057-62
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4) Misu K, Hattori N, Nagamatsu M, et al. Late-onset familial amyloid polyneuropathy type I (transthyretin Met30-associated familial amyloid polyneuropathy) unrelated to endemic focus in Japan. Brain. 1999; 122: 1951-62
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5) Holmgren G, Steen L, Ekstedt J, et al. Biochemical effect of liver transplantation in two Swedish patients with familial amyloidotic polyneuropathy (FAP-met30). Clin Genet. 1991; 40: 242-6
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6) FAP WTR http:///www.fapwtr.org/
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7) Takei Y, Ikeda S, Ikegami T, et al. Ten years of experience with liver transplantation for familial amyloid polyneuropathy in Japan: Outcomes of living donor liver transplantations. Intern Med. 2005; 44: 1151-6
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8) Ando Y, Tanaka Y, Ando E, et al. Effect of liver transplantation on autonomic dysfunction in familial amyloidotic polyneuropathy type I. Lancet. 1995; 345: 195-6
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9) Ando Y, Ando E, Tanaka Y, et al. De novo amyloid synthesis in ocular tissue in familial amyloidotic polyneuropathy after liver transplantation. Transplantation. 1996; 62: 1037-8
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10) Stangou AJ, Hawkins PN, Heaton ND, et al. Progressive cardiac amyloidosis following liver transplantation for familial amyloid polyneuropathy: implications for amyloid fibrillogenesis. Transplantation. 1998; 66: 229-33
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11) Suhr OB, Friman S, Ericzonet B. Early liver transplantation improves familial amyloidotic polyneuropathy patientsʼ survival. Amyloid. 2005; 12: 233-8
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12) Ando Y, Terazaki H, Nakamura M, et al. A different amyloid formation mechanism: De novo oculoleptomeningeal amyloid deposits after liver transplantation. Transplantation. 2004; 77: 345-9
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13) Sakashita N, Ando Y, Haraoka K, et al. Severe congestive heart failure with cardiac liver cirrhosis 10 years after orthotopic liver transplantation for familial amyloidotic polyneuropathy. Pathol Int. 2006; 56: 408-12
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14) Ando E, Ando Y, Haraoka K. Ocular amyloid imvolvement after liver transplantation for polyneuropathy. Ann Intern Med. 2001; 135: 931-2
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15) Stangou AJ, Heaton ND, Hawkins PN, et al. Transmission of systemic transthyretin amyloidosis by means of domino liver transplantation. N Engl J Med. 2005; 352: 2356
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16) Goto T, Yamashita T, Ueda M, et al. Iatrogenic amyloid neuropathy in a Japanese patient after sequential liver transplantation. Am J Transplant. 2006; 6: 2512-5
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17) Ando Y, Suhr OB. Autonomic dysfunction in familial amyloidotic polyneuropathy (FAP). Amyloid. 1998; 5: 288-300
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18) Ando E, Ando Y, Okumura R, et al. Ocular manifestations of familial amyloidotic polyneu-ropathy type I: long-term follow up. Br J Ophthalmol. 1997; 81: 295-8
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19) Sekijima Y, Dendle MA, Kelly JW. Orally administered diflunisal stabilizes transthyretin against dissociation required for amyloidogenesis. Amyloid. 2006; 13: 236-49
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20) Sekijima Y, Tojo K, Morita H, et al. Long-term effects of diflunisal on familial amyloid polyneuropathy. The VIIth international symposium on familial amyloidotic polyneuropathy (abtract). London: 2008. p.5-6
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21) Berk JL, Dyck PJ, Obici L, et al. The diflunisal trial: update on study drug tolerance and disease progression. Amyloid. 2010; 17(Suppl 1): 78
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22) Waddington-Cruz M, Coelho T, Maia L, et al. A landmark clinical trial of a novel small molecule transthyretin (TTR) stabilizer, Fx-1006A, in patients with TTR amyloid polyneuropathy: a phase II/III, randomized, double-blind, placebo-controlled study. J Neurol. 2008; 255(Suppl 2): 107
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23) Sato T, Ando Y, Susuki S, et al. Chromium (III) ion and thyroxine cooperate to stabilize the transthyretin tetramer and suppress in vitro amyloid fibril formation. FEBS lett. 2006; 580: 491-6
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24) Nakamura M, Ando Y, Nagahara S, et al. Targeted conversion of the transthyretin gene in vitro and in vivo. Gene Ther. 2004; 11: 838-46
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25) Ando Y. Liver transplantation and new therapeutic approaches for familial amyloidotic polyneuropathy (FAP). Med Mol Morphol. 2005; 38: 142-54
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26) Benson MD, Kluve-Beckerman B, Zeldenrust SR, et al. Targeted suppression of an amyloidogenic transthyretin with antisense oligonucleotides. Muscle Nerve. 2006; 33: 609-18
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27) Kurosawa T, Igarashi S, Nishizawa M, et al. Selective silencing of a mutant transthyretin allele by small interfering RNAs. Biochem Biophys Res Commun. 2005; 337: 1012-8
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28) Terazaki H, Ando Y, Fernandes R, et al. Immunization in familial amyloidotic polyneuropathy: counteracting deposition by immunization with a Y78F TTR mutant. Lab Invest. 2006; 86: 23-31
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29) Bergström J, Engström U, Yamashita T, et al. Surface exposed epitopes and structural heterogeneity of in vivo formed transthyretin amyloid fibrils. Biochem Biopys Res Commun. 2006; 348: 532-9
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30) Ando Y, Nakamura M, Ueda M, et al. New therapeutic approaches for familial amyloidotic polyneuropathy (FAP). In: Richardoson SJ, Cody V. Recent advances in transthyretin evolution, structure, and biological functions. Berlin Heidelberg: Springer-Verlag; 2009. p.215-38
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31) Ueda M, Ando Y, Hakamata Y. A transgenic rat with the human ATTR V30M: a novel tool for analyses of ATTR metabolisms. Biochem Biophys Res Commun. 2007; 352: 299-304
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32) ZMacedo B, Batista AR, Ferreira N, et al. Anti-apoptotic treatment reduces transthyretin deposition in a transgenic mouse model of familial amyloidotic polyneuropathy. Biophys Acta. 2008; 1782: 517-22
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33) Kawaji T, Ando Y, Hara R, et al. Novel therapy for transthyretin-related ocular amyloidosis: a pilot study of retinal laser photocoagulation. Ophthalmology. 2010; 117: 552-5
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