|
1) Manolio TA. Genomewide association studies and assessment of the risk of disease. N Engl J Med. 2010; 363: 166-76
|
|
|
|
2) Kabesch M. Novel asthma-associated genes from genome-wide association studies: what is their significance？ Chest. 2010; 137: 909-15
|
|
|
|
|
|
3) Cirulli ET, Goldstein DB. Uncovering the roles of rare variants in common disease through whole-genome sequencing. Nat Rev Genet. 2010; 11: 415-25
|
|
|
|
|
|
4) Moffatt MF, Kabesch M, Liang L, et al. Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature. 2007; 448: 470-3
|
|
|
|
|
|
5) Hirota T, Harada M, Sakashita M, et al. Genetic polymorphism regulating ORM1-like 3 (Saccharomyces cerevisiae) expression is associated with childhood atopic asthma in a Japanese population. J Allergy Clin Immunol. 2008; 121: 769-70
|
|
|
|
|
|
6) Tavendale R, Macgregor DF, Mukhopadhyay S, et al. A polymorphism controlling ORMDL3 expression is associated with asthma that is poorly controlled by current medications. J Allergy Clin Immunol. 2008; 121: 860-3
|
|
|
|
|
|
7) Galanter J, Choudhry S, Eng C, et al. ORMDL3 gene is associated with asthma in three ethnically diverse populations. Am J Respir Crit Care Med. 2008; 177: 1194-200
|
|
|
|
|
|
8) Sleiman PM, Annaiah K, Imielinski M, et al. ORMDL3 variants associated with asthma susceptibility in North Americans of European ancestry. J Allergy Clin Immunol. 2008; 122: 1225-7
|
|
|
|
|
|
9) Bisgaard H, Bφnnelykke K, Sleiman PM, et al. Chromosome 17q21 gene variants are associated with asthma and exacerbations but not atopy in early childhood. Am J Respir Crit Care Med. 2009; 179: 179-85
|
|
|
|
|
|
10) Himes BE, Hunninghake GM, Baurley JW, et al. Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene. Am J Hum Genet. 2009; 84: 581-93
|
|
|
|
|
|
11) Mathias RA, Grant AV, Rafaels N, et al. A gen-ome-wide association study on African-ancestry populations for asthma. J Allergy Clin Immunol. 2010; 125: 336-46
|
|
|
|
|
|
12) Sleiman PM, Flory J, Imielinski M, et al. Variants of DENND1B associated with asthma in children. N Engl J Med. 2010; 362: 36-44
|
|
|
|
|
|
13) Li X, Howard TD, Zheng SL, et al. Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions. J Allergy Clin Immunol. 2010; 125: 328-35
|
|
|
|
|
|
14) Silverman EK. Progress in chronic obstructive pulmonary disease genetics. Proc Am Thorac Soc. 2006; 3: 405-8
|
|
|
|
|
|
15) Cho MH, Boutaoui N, Klanderman BJ, et al. Variants in FAM13A are associated with chronic obstructive pulmonary disease. Nat Genet. 2010; 42: 200-2
|
|
|
|
|
|
16) Hancock DB, Eijgelsheim M, Wilk JB, et al. Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function. Nat Genet. 2010; 42: 45-52
|
|
|
|
|
|
17) Schünemann HJ, Dorn J, Grant BJ, et al. Pulmonary function is a long-term predictor of mortality in the general population: 29-year follow-up of the Buffalo Health Study. Chest. 2000; 118: 656-64
|
|
|
|
|
|
18) Repapi E, Sayers I, Wain LV, et al. Genome-wide association study identifies five loci associated with lung function. Nat Genet. 2010; 42: 36-44
|
|
|
|
|
|
19) Weiss ST. Lung function and airway diseases. Nat Genet. 2010; 42: 14-6
|
|
|
|
|
|
20) Amos CI, Spitz MR, Cinciripini P. Chipping away at the genetics of smoking behavior. Nat Genet. 2010; 42: 366-8
|
|
|
|
|
|
21) Liu JZ, Tozzi F, Waterworth DM, et al. Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet. 2010; 42: 436-40
|
|
|
|
|
|
22) Thorgeirsson TE, Gudbjartsson DF, Surakka I, et al. Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. Nat Genet. 2010; 42: 448-53
|
|
|
|
|
|
23) Tobacco and Genetics Consortium. Genome-wide meta-analyses identify multiple loci associated with smoking behavior. Nat Genet. 2010; 42: 441-7
|
|
|
|
|