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2) Kozik DJ, Tweddell JS. Characterizing the inflammatory response to cardiopulmonary bypass in children. Ann Thorac Surg. 2006; 81: S2347-54
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3) Menasche P. The inflammatory response to cardiopulmonary bypass and its impact on postoperative myocardial function. Curr Opin Cardiol. 1995; 10: 597-604
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4) 高橋幸宏. 無輸血心臓手術(小児). In: 小柳 仁, 北村惣一郎, 安井久喬, 編. 心臓血管外科手術書. 東京: 先端医療技術研究所; 2002. p.21-30
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7) Jaggers J, Lawson JH. Coagulopathy and inflammation in neonatal heart surgery: Mecha-nism and strategies. Ann Thorac Surg. 2006; 81: S23606-6
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8) Deptula J, Glogowski K, Merrigan K, et al. Evaluation of biocompatible cardiopulmonary bypass circuit use during pediatric open heart surgery. JECT. 2006; 38: 22-6
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9) Suzuki Y, Daitoku K, Minakawa M, et al. Poly-2-methoxyethylacrylate- coated bypass circuits reduce activation of coagulation system and inflammatory response in congenital cardiac surgery. J Artif Organs. 2008; 11: 111-6
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10) Jensen E, Andreasson S, Bengtsson A, et al. Influence of two different perfusion systems on inflammatory response in pediatric heart surgery. Ann Thorac Surg. 2003; 75: 919-25
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12) Schroeder VA, Pearl JM, Schwartz SM, et al. Combined steroid treatment for congenital heart surgery improves oxygen delivery and reduces post bypass inflammatory mediator expression. Circulation. 2003; 107; 2823-8
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13) Bronicki RA, Backer CL, Baden HP, et al. Dexamethasone reduces the inflammatory response to cardiopulmonary bypass in children. Ann Thorac Surg. 2000; 69: 1490-95
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15) Checchia PA, Backer CL, Bronicki RA, et al. Dexamethasone reduces postoperative troponin levels in children undergoing cardiopulmonary bypass. Crit Care Med. 2003; 31: 1742-5
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16) Lodge AJ, Chai PJ, Daggett CW, et al. Methylprednisolone reduces the inflammatory response to cardiopulmonary bypass in neonatal piglets: Timing of dose is important. J Thorac Cardiovasc Surg. 1999; 117: 515-22
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17) Gessler P, Hohl V, Carrel T, et al. Administration of steroids in pediatric cardiac surgery: impact on clinical outcome and systemic inflammatory response. Pediatr Cardiol. 2005; 26: 595-600
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18) Lindberg L, Forsell C, Jogi P, et al. Effects of dexamethasone on clinical course, C-reactive protein, S100B protein and von Willebrand factor antigen after paediatric cardiac surgery. Br J Anaesth. 2003; 90: 728-32
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19) Shum-Tim D, Tchervenkov C, Jamal AM, et al. Systemic steroid pretreatment improves cerebral protection after circulatory arrest. Ann Thorac Surg. 2001; 72: 1465-72
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20) Langley SM, Chai PJ, Jaggers JJ, et al. Preoperative high dose methylprednisolone attenuates the cerebral response to deep hypothermic circulatory arrest. Eur J Cardiothorac Surg. 2000; 17: 279-86
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21) Ando M, Park In-Sam, Wada N, et al. Steroid supplementation: A legitimate pharmacotherapy after neonatal open heart surgery. Ann Thorac Surg. 2005; 80: 1672-8
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22) Mossinger H, Dietrich W. Activation of hemostasis during cardiopulmonary bypass and pediatric aprotinin dosage. Ann Thorac Surg. 1998; 65: S45-51
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23) Davies MJ, Allen A, Kort H, et al. Prospective, randomized, doubleblind study of high-dose aprotinin in pediatric cardiac operation. Ann Thorac Surg. 1997; 63: 467-503
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24) Mojcik CF, Levy JH. Aprotinin and systemic inflammatory response after cardiopulmonary bypass. Ann Thorac Surg. 2001; 71: 745-54
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25) Aoki M, Jonas RA, Nomura F, et al. Aprotinin enhances acute recovery of cerebral metabolism after circulatory arrest. Circulation. 1993; 86: S182
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26) Kahn MMH, Gikakis N, Miyamoto S, et al. Aprotinin inhibits thrombin formation and monocyte tissue factor in simulated cardio-pulmonary bypass. Ann Thorac Surg. 1999; 68: 473-8
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27) Toyama S, Hatori F, Shimizu, et al. A neutrophil elastase inhibitor, sivelestat, improved respiratory and cardiac function in pediatric cardiovascular surgery with cardiopulmonary bypass. J Anesth. 2008; 22: 341-46
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28) Ando M, Murai T, Takahashi Y. The effects of sivelestat sodium on post-cardiopulmonary bypass acute lung injury in a neonatal piglet model. ICVTS. 2008; 7: 785-88
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29) Hyllner M, Arnestad JP, Bengtson JP, et al. Complement activation during storage of whole blood, red cells, plasma, and byffy coat. Transfusion. 1997; 37: 264-8
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31) Hyllner M. Tylman M, Bengtson JP, et al. Complement activation in prestorage leucocyte-filtered plasma. Transfu Med. 2004; 14: 45-52
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32) Sakurai H, Maeda M, Murase M, et al. Hemofiltration removes bradykinin generated in the priming blood in cardiopulmonary bypass during circulation. Ann Thorac Cardiovasc Surg. 1998; 4: 59
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33) 高橋幸宏. 人工心肺技術の進歩と無輸血手術(小児). In: 細田瑳一, 篠山重威, 北村惣一郎, 監修. 心臓病 診断と治療の最前線. 東京: 先端医療技術研究所; 2004. p.229-36
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34) Hickey E, Karamlou T, Ungerleider RM. Effects of circuit miniaturization in reducing inflammatory response to infant cardiopulmonary bypass by elimination of allogeneic blood products. Ann Thorac Surg. 2006; 81: S2367-72
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35) 高橋雅彦. 輸血副作用の基礎知識. 薬局. 2004; 55: 54-62
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36) Bando K, Turrentine MW, Vijay P, et al. Effect of modified ultrafiltration in high-risk patients undergoing operations for congenital heart disease. Ann Thorac Surg. 1998; 66: 821-8
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37) Journois D, Israel-Biet D, Pouard P, et al. High-volume, zero-balanced hemodilution to reduce delayed inflammatory response to cardio-pulmonary bypass in children. Anesthesiology. 1996; 85: 965-76
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38) Naik SK, Knight A, Elliott MJ. A successful modification of ultrafiltration for cardiopulmonary bypass in children. Perfusion. 1991; 6: 41-50
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39) Naik SK, Knight A, Elliott MJ. A prospective randomized study of a modified technique of ultrafiltration during pediatric open-heart surgery. Circulation. 1991; 84 Suppl: III-422-31
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40) Naik SK, Balaji S, Elliot MJ. Modified ultrafiltration improves hemodynamics after cardiopulmonary bypass in children. [abstract]. J Am Coll Cardiol. 1993; 19: 37
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41) Davies MJ, Nguyen K, Gaynor JW, et al. Modified ultrafiltration improves left ventricular systolic function in infants after cardiopulmonary bypass. J Thorac Cardiovasc Surg. 1998; 1115: 361-70
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42) Chaturvedi RR, Shore DF, White PA, et al. Modified ultrafiltration improves global left ventricular systolic function after open-heart surgery in infants and children. Eur J Cardiothorac Surg. 1999; 15: 742-6
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43) Koutlas TC, Gaynor JW, Nicolson SC, et al. Modified ultrafiltration reduces postoperative morbidity after cavopulmonary connection. Ann Thorac Surg. 1997; 64: 37-43
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44) Daggett CW, Lodge AJ, Scarborough JE, et al. Modified ultrafiltration versus conventional ultrafiltration: a randomized prospective study in neonatal piglets. J Thorac Cardiovasc Surg. 1998; 115: 336-42
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45) Bando K, Vijay P, Sharp TG, et al. Dilutional and modified ultrafiltration reduces pulmonary hypertension after operations for congenital heart disease: a prospective randomized study. J Thorac Cardiovasc Sur. 1998; 115: 517-27
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46) Journois D, Pouard P, Greeley WJ, et al. Hemofiltration during cardiopulmonary bypass in pediatric cardiac surgery. Anesthesiology. 1994; 81: 1181-9
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47) Koutlas TC, Gaynor JW, Nicolson SC, et al. Modified ultrafiltration reduces postoperative morbidity after cavopulmonary connection. Ann Thorac Surg. 1997; 64; 37-43
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48) Meliones JN, Gayner JW, Wilson BG, et al. Modified ultrafiltration reduces airway pressures and improves lung compliance after congenital heart surgery. J Am Coll Cardiol. 1995; 25: 271
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49) Skaryak LA, Kirshbom PM, Dibernardo LR, et al. Modified ultrafiltration improves cerebral metabolic recovery after circulatory arrest. J Thorac Cardiovasc Surg. 1995; 109: 744-52
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50) Yokoyama K, Takabayashi S, Komada T, et al. Removak of prostaglandein E2 and increased intraoperative blood pressuer during modified ultrafiltration in prdiatric cardiac surgery. J Thorac Cardiovasc Surg. 2009; 137: 730-5
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51) Elliott MJ. Modified ultrafiltration and open heart surgery in children. Paediatr Anaesth. 1999; 9: 1-5
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52) Wang MJ, Chiu IS, Hsu CM, et al. Efficacy of ultrafiltration in removing inflammatory mediators during pediatric cardiac operations. Ann Thorac Surg. 1996; 61: 651-6
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53) Gaynor JW. Use of modifies ultrafiltration after repair of congenital heart defects. Semin Thorac Cardiovasc Surg. 1998 1: 81-90
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54) 高橋幸宏. 先天性心疾患手術. In: 小川 龍, 坂本篤裕, 高尾あや子, 編. 最近の心臓手術と麻酔管理のながれ. 東京: 真興交易医書出版部; 1999. p.143
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