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1) Dann SG, Thomas G. The amino acid sensitive TOR pathway from yeast to mammals. FEBS Lett. 2006; 580: 2821-9
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2) Yang Q, Guan KL. Expanding mTOR signaling. Cell Res. 2007; 17: 666-81
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3) Proud CG. mTOR-mediated regulation of translation factors by amino acids. Biochem Biophys Res Commun. 2004; 313: 429-36
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4) Kim E. Mechanisms of amino acid sensing in mTOR signaling pathway. Nutr Res Pract. 2009; 3: 64-71
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5) Fox HL, Kimball SR, Jefferson LS, et al. Amino acids stimulate phosphorylation of p70S6k and organization of rat adipocytes into multicellular clusters. Am J Physiol. 1998; 274: C206-13
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6) Wang X, Campbell LE, Miller CM, et al. Amino acid availability regulates p70 S6 kinase and multiple translation factors. Biochem J. 1998; 334: 261-7
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7) Chritensen HN. Role of amino acid transport and countertransport in nutrition and metabolism. Physiol Rev. 1990; 70: 43-77
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8) 金井好克. 腫瘍細胞のアミノ酸トランスポーターの発現とそれを標的とした診断と治療への応用の可能性. 膜. 2008; 33: 108-17
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9) Kanai Y, Segawa H, Miyamoto K, et al. Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen (CD98). J Biol Chem. 1998; 273: 23629-32
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10) Pineda M, Fernandez E, Torrents D, et al. Identification of a membrane protein, LAT2, that co-expresses with 4F2 heavy chain, an L-type amino acid transport activity with broad specificity for small and large zwitterionic amino acids. J Biol Chem. 1999; 274: 19738-44
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11) Segawa H, Fukasawa Y, Miyamoto K, et al. Identification and functional characterization of a Na+-independent neutral amino acid transporter with broad substrate selectivity. J Biol Chem. 1999; 274: 19745-51
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12) Rossier G, Meier C, Bauch C, et al. LAT2, a new basolateral 4F2hc/CD98-associated amino acid transporter of kidney and intestine. J Biol Chem. 1999; 274: 34948-54
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13) Dave MH, Schulz N, Zecevic M, et al. Expression of heteromeric amino acid transporters along the murine intestine. J Physiol. 2004; 558: 597-10
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14) Park SY, Kim JK, Kim IJ, et al. Reabsorption of neutral amino acids mediated by amino acid transporter LAT2 and TAT1 in the basolateral membrane of proximal tubule. Arch Pharm Res. 2005; 28: 421-32
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15) Babu E, Kanai Y, Chairoungdua A, et al. Identification of a novel system L amino acid transporter structurally distinct from heterodimeric amino acid transporters. J Biol Chem. 2003; 278: 43838-45
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16) Bodoy S, Martin L, Zorzano A, et al. Identification of LAT4, a novel amino acid transporter with system L activity. J Biol Chem. 2005; 280: 12002-11
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17) Nakanishi K, Matsuo H, Kanai Y, et al. LAT1 expression in normal lung and in atypical adenomatous hyperplasia and adenocarcinoma of the lung. Virchows Arch. 2005; 21: 1-9
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18) Yanagida O, Kanai Y, Chairoungdua A, et al. Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines. Biochim Biophys Acta. 2001; 1514: 291-302
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19) Fukuhara D, Kanai Y, Chairoungdua A, et al. Protein characterization of Na+ -independent system L amino acid transporter 3 in mice. Am J Pathol. 2007; 170: 888-98
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20) Sekine Y, Nishibori Y, Akimoto Y, et al. Amino acid transporter LAT3 is required for podocyte development and function. J Am Soc Nephrol. 2009; 20: 1586-96
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21) Adibi SA, Drash AL. Hormone and amino acid levels in altered nutritional states. J Lab Clin Med. 1970; 76: 722-32
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22) Adibi SA. Influence of dietary deprivations on plasma concentration of free amino acids of man. J Appl Physiol. 1968; 25: 52-7
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23) Felig P, Owen OE, Wahren J, et al. Amino acid metabolism during prolonged starvation. J Clin Invest. 1969; 48: 584-94
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24) Swendseid ME, Umezawa CY, Drenick E. Plasma amino acid levels in obese subjects before, during, and after starvation. Am J Clin Nutr. 1969; 22: 740-3
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25) Ahlman B, Andersson K, Leijonmarck CE, et al. Short-term starvation alters the free amino acid content of the human intestinal mucosa. Clin Sci (Lond). 1994; 86: 653-62
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26) Holecek M, Sprongl L, Tilser I. Metabolism of branched-chain amino acids in starved rats: the role of hepatic tissue. Physiol Res. 2001; 50: 25-33
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27) Van Winkle LJ. Amino acid transport regulation and early embryo development. Biol Reprod. 2001; 64: 1-12
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28) Kurayama R, Ito N, Nishibori Y, et al. Role of mTORC1 activation interacting with amino acid transporter LAT2 in glomerular crescent formation. In revision
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29) Morimoto E, Kanai Y, Kim do K, et al. Establishment and characterization of mammalian cell lines stably expressing human L-type amino acid transporters. J Pharmacol Sci. 2008; 108: 505-16
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