1) Greenberg AS, Egan JJ, Wek SA, et al. Perilipin, a major hormonally regulated adipocyte-specific phosphoprotein associated with the periphery of lipid storage droplets. J Biol Chem. 1991; 266: 11341-6
|
|
|
2) Servetnick DA, Brasaemle DL, Gruia-Gray J, et al. Perilipins are associated with cholesteryl ester droplets in steroidogenic adrenal cortical and Leydig cells. J Biol Chem. 1995; 270: 16970-3
|
|
|
3) Belfrage P, Fredrikson G, Olsson H, et al. Hormonal regulation of adipose tissue lipolysis by reversible phosphorylation of hormone-sensitive lipase. Prog Clin Biol Res. 1982; 102 Pt C: 213-23
|
|
|
4) Egan JJ, Greenberg AS, Chang MK, et al. Mechanism of hormone-stimulated lipolysis in adipocytes: translocation of hormone-sensitive lipase to the lipid storage droplet. Proc Natl Acad Sci U S A. 1992; 89: 8537-41
|
|
|
5) Brasaemle DL, Rubin B, Harten IA, et al. Perilipin A increases triacylglycerol storage by decreasing the rate of triacylglycerol hydrolysis. J Biol Chem. 2000; 275: 38486-93
|
|
|
6) Souza SC, Muliro KV, Liscum L, et al. Modulation of hormone-sensitive lipase and protein kinase A-mediated lipolysis by perilipin A in an adeno-viral reconstituted system. J Biol Chem. 2002; 277: 8267-72
|
|
|
7) Martinez-Botas J, Anderson JB, Tessier D, et al. Absence of perilipin results in leanness and reverses obesity in Lepr(db/db) mice. Nat Genet. 2000; 26: 474-9
|
|
|
8) Tansey JT, Sztalryd C, Gruia-Gray J, et al. Perilipin ablation results in a lean mouse with aberrant adipocyte lipolysis, enhanced leptin production, and resistance to diet-induced obesity. Proc Natl Acad Sci U S A. 2001; 98: 6494-9
|
|
|
9) Zimmermann R, Strauss JG, Haemmerle G, et al. Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase. Science. 2004; 306: 1383-6
|
|
|
10) Brasaemle DL. Thematic review series: adipocyte biology. The perilipin family of structural lipid droplet proteins: stabilization of lipid droplets and control of lipolysis. J Lipid Res. 2007; 48: 2547-59
|
|
|
11) Londos C, Sztalryd C, Tansey JT, et al. Role of PAT proteins in lipid metabolism. Biochimie. 2005; 87: 45-9
|
|
|
12) Osuga J, Ishibashi S, Oka T, et al. Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesity. Proc Natl Acad Sci U S A. 2000; 97: 787-92
|
|
|
13) Okazaki H, Igarashi M, Nishi M, et al. Identifi-cation of a novel member of the carboxylesterase family that hydrolyzes triacylglycerol: a potential role in adipocyte lipolysis. Diabetes. 2006; 55: 2091-7
|
|
|
14) Brasaemle DL, Levin DM, Adler-Wailes DC, et al. The lipolytic stimulation of 3T3-L1 adipocytes promotes the translocation of hormone-sensitive lipase to the surfaces of lipid storage droplets. Biochim Biophys Acta. 2000; 1483: 251-62
|
|
|
15) Miyoshi H, Souza SC, Zhang HH, et al. Perilipin promotes hormone-sensitive lipase-mediated adipocyte lipolysis via phosphorylation-depen-dent and -independent mechanisms. J Biol Chem. 2006; 281: 15837-44
|
|
|
16) Shen WJ, Patel S, Miyoshi H, et al. Functional interaction of hormone-sensitive lipase and perilipin in lipolysis. J Lipid Res. 2009 Jun 10. [Epub ahead of print]
|
|
|
17) Lass A, Zimmermann R, Haemmerle G, et al. Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome. Cell Metab. 2006; 3: 309-19
|
|
|
18) Yamaguchi T, Omatsu N, Matsushita S, et al. CGI-58 interacts with perilipin and is localized to lipid droplets. Possible involvement of CGI-58 mislocalization in Chanarin-Dorfman syndrome. J Biol Chem. 2004; 279: 30490-7
|
|
|
19) Granneman JG, Moore HP, Granneman RL, et al. Analysis of lipolytic protein trafficking and interactions in adipocytes. J Biol Chem. 2007; 282: 5726-35
|
|
|
20) Haemmerle G, Lass A, Zimmermann R, et al. Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase. Science. 2006; 312: 734-7
|
|
|
21) Cohen AW, Razani B, Schubert W, et al. Role of caveolin-1 in the modulation of lipolysis and lipid droplet formation. Diabetes. 2004; 53: 1261-70
|
|
|
22) Miyoshi H, Perfield JW 2nd, Obin MS, et al. Adipose triglyceride lipase regulates basal lipolysis and lipid droplet size in adipocytes. J Cell Biochem. 2008; 105: 1430-6
|
|
|
23) Xu G, Sztalryd C, Londos C. Degradation of perilipin is mediated through ubiquitination-proteasome pathway. Biochim Biophys Acta. 2006; 1761: 83-90
|
|
|
24) Jiang HP, Serrero G. Isolation and charac-terization of a full-length cDNA coding for an adipose differentiation-related protein. Proc Natl Acad Sci U S A. 1992; 89: 7856-60
|
|
|
25) Gross DN, Miyoshi H, Hosaka T, et al. Dynamics of lipid droplet-associated proteins during hormonally stimulated lipolysis in engineered adipocytes: stabilization and lipid droplet binding of adipocyte differentiation-related protein/adipophilin. Mol Endocrinol. 2006; 20: 459-66
|
|
|
26) Nishino N, Tamori Y, Tateya S, et al. FSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets. J Clin Invest. 2008; 118: 2808-21
|
|
|
27) Greenberg AS, Egan JJ, Wek SA, et al. Isolation of cDNAs for perilipins A and B: sequence and expression of lipid droplet-associated proteins of adipocytes. Proc Natl Acad Sci U S A. 1993; 90: 12035-9
|
|
|
28) Zhang HH, Souza SC, Muliro KV, et al. Lipase-selective functional domains of perilipin A differentially regulate constitutive and protein kinase A-stimulated lipolysis. J Biol Chem. 2003; 278: 51535-42
|
|
|
29) Miyoshi H, Perfield JW 2nd, Souza SC, et al. Control of adipose triglyceride lipase action by serine 517 of perilipin A globally regulates pro-tein kinase A-stimulated lipolysis in adipocytes. J Biol Chem. 2007; 282: 996-1002
|
|
|
30) Mottagui-Tabar S, Rydén M, Löfgren P, et al. Evidence for an important role of perilipin in the regulation of human adipocyte lipolysis. Diabetologia. 2003; 46: 789-97
|
|
|
31) Wang Y, Sullivan S, Trujillo M, et al. Perilipin expression in human adipose tissues: effects of severe obesity, gender, and depot. Obes Res. 2003; 11: 930-6
|
|
|
32) Souza SC, de Vargas LM, Yamamoto MT, et al. Overexpression of perilipin A and B blocks the ability of tumor necrosis factor alpha to increase lipolysis in 3T3-L1 adipocytes. J Biol Chem. 1998; 273: 24665-9
|
|
|
33) Kahn CR. Medicine. Can we nip obesity in its vascular bud? Science. 2008; 322: 542-3
|
|
|
34) Souza SC, Christoffolete MA, Ribeiro MO, et al. Perilipin regulates the thermogenic actions of norepinephrine in brown adipose tissue. J Lipid Res. 2007; 48: 1273-9
|
|
|