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21) Schermuly RT, Stasch JP, Pullamsetti SS, et al. Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension. Eur Respir J. 2008; 32: 881-91
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24) Mittendorf J, Weigand S, Alonso-Alija C, et al. Discovery of riociguat (BAY 63-2521): a potent, oral stimulator of soluble guanylate cyclase for the treatment of pulmonary hypertension. Chem Med Chem. 2009; 4: 853-65
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25) Evgenov OV, Kohane DS, Bloch KD, et al. Inhaled agonists of soluble guanylate cyclase induce selective pulmonary vasodilation. Am J Respir Crit Care Med. 2007; 176: 1138-45
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26) Lapp H, Mitrovic V, Franz N, et al. Cinaciguat (BAY 58-2667) improves cadiopulmonary hemodynamics in patients with acute decompensated heart failure. Circulation. 2009; 119: 2781-8
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28) Blaukovitsch M, Zabel P, Hauber HP. Vasoproliferation and antiproliferative treatment options in pulmonary arterial hypertension. Rec Pat Cardiovasc Drug Discov. 2009; 4: 142-9
医中誌リンクサービス
29) McMurtry MS, Bonnet S, Michelakis ED, et al. Statin therapy, alone or with rapamycin, does not reverse monocrotaline pulmonary arterial hypertension; the rapamysin-atorvastatin-simvastatin study. Am J Physiol Lung Cell Mol Physiol. 2007; 293: L933-40
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30) Oka M, Fagan KA, Jones PL, et al. Therapeutic potential of RhoA/Rho kinase inhibitors in pulmonary hypertension. Br J Pharmacol. 2008; 155: 444-54
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31) Jiang BH, Tawara S, Abe K, et al. Acute vasodilator effect of fasudil, a Rho-kinase inhibitor, in monocrotaline-induced pulmonary hypertension in rats. J Cardiovasc Pharmacol. 2007; 49: 85-9
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33) Kozhevnikova VV, Medvedeva NA. Chronic administration of serotonin transporter inhibitor (Fluoxetin) decreases monocrotaline-induced pulmonary hypertension in rats. Eksp Klin Farmakol. 2007; 70: 15-8
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34) Hoeper MM, Ghofrani HA, Grimminger F, et al. Dana Point: What is new in the treatment pulmonary hypertension? Dtsch Med Wochenschr. 2008; 133 Suppl 6: S191-5
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35) Guilluy C, Eddahibi S, Agard C, et al. RhoA and Rho kinase activation in human pulmonary hypertension. Role of 5-HT signaling. Am J Respir Crit Care Med. 2009: 179: 1151-8
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36) Ferreira AJ, Shenoy V, Yamazato Y, et al. Evidence for angiotensin-converting enzyme 2 as a therapeutic target for the prevention of pulmonary hypertension. Am J Respir Crit Care Med. 2009; 179: 1048-54
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37) Zhao YD, Courtman DW, Deng Y, et al. Rescue of monocrotaline-induced pulmonary arterial hypertension using bone marrow-derived endothelial-like progenitor cells: efficacy of combined cell and eNOS gene therapy in established disease. Circ Res. 2005; 96: 442-50
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38) Grigg A, Buchanan M, Whitford H. Late-onset pulmonary arterial hypertension in association with graft-versus-host disease after allogeneic stemm-cell transplantation. Am J Hematol. 2005; 80: 38-42
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39) Shantsila E, Watson T, Lip GYH, et al. Endothelial progenitor cells in cardiovascular disorders. J Am Coll Cardiol. 2007; 49: 741-52
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40) Diller GD, van Eijl S, Okonko DO, et al. Circulating endothelial progenitor cells in patients with Eisenmenger syndrome and idiopathic pulmonary arterial hypertension. Circulation. 2008; 117: 3020-30
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41) Wang XX, Zhang FR, Shang YP, et al. Transplantation of autologous endothelial progenitor cells may be beneficial in patients with idiopathic pulmonary arterial hypertension: a pilot randomized controlled trial. J Am Coll Cardiol. 2007; 49: 1566-71
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42) Smadja DM, Gaussem P, Mauge L, et al. Circulating endothelial cells. Circulation. 2009; 119: 374-81
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43) Raoul W, Wagner-Ballon O, Saber G, et al. Effects of bone marrow-derived cells on monocrotaline- and hypoxia-induced pulmonary hypertension in mice. Respir Res. 2007; 8: 8
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44) Satoh K, Kagaya Y, Nakano M, et al. Important role of endogenous erythropoietin system in recruitment of endothelial progenitor cells in hypoxia-induced pulmonary hypertension in mice. Circulation. 2006; 113: 1442-50
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