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1) 日本臨床腎移植学会. 腎移植臨床登録集計報告(2007)-3 2006年経過追跡調査結果. 移植. 2007; 42: 545-57
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2) Penn I. Post-transplant malignancy: the role of immunosuppression. Drug Saf. 2000; 23: 101-13
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3) Buell JF, Gross TG, Woodle ES. Malignancy after transplantation. Transplantation. 2005; 80: S254-64
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4) Grulich AE, van Leeuwen MT, Falster MO, et al. Incidence of cancers in people with HIV/AIDS compared with immunosuppressed transplant recipients: a meta-analysis. Lancet. 2007; 370: 59-67
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5) 今西正昭, 国方聖司, 秋山隆弘, 他. 当科における腎移植後の悪性腫瘍7例の検討及び本邦における腎移植後の悪性腫瘍の統計. 移植. 1996; 31: 100-7
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6) Sheil AG, Disney AP, Mathew TH, et al. De novo malignancy emerges as a major cause of morbidity and late failure in renal transplantation. Transplant Proc. 1993; 25: 1383-4
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7) 野島道生. 腎移植後の悪性腫瘍とPTLD アンケートによる症例調査とスクリーニングの状況. 今日の移植. 2008; 21: 279-84
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8) Kauffman HM, Cherikh WS, McBride MA, et al. Post-transplant de novo malignancies in renal transplant recipients: the past and present. Transpl Int. 2006; 19: 607-20
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9) Kasiske BL, Snyder JJ, Gilbertson DT, et al. Cancer after kidney transplantation in the United States. Am J Transplant. 2004; 4: 905-13
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10) Webster AC, Craig JC, Simpson JM, et al. Identifying high risk groups and quantifying absolute risk of cancer after kidney transplantation: a cohort study of 15, 183 recipients. Am J Transplant. 2007; 7: 2140-51
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11) Dantal J, Hourmant M, Cantarovich D, et al. Effect of long-term immunosuppression in kidney-graft recipients on cancer incidence: randomised comparison of two cyclosporin regimens. Lancet. 1998; 351: 623-8
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12) Imao T, Ichimaru N, Takahara S, et al. Risk factors for malignancy in Japanese renal transplant recipients. Cancer. 2007; 109: 2109-15
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13) Kauffman HM. Malignancies in organ transplant recipients. J Surg Oncol. 2006; 94: 431-3
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14) Myron Kauffman H, McBride MA, Cherikh WS, et al. Transplant tumor registry: donor related malignancies. Transplantation. 2002; 74: 358-62
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15) European best practice guidelines for renal transplantation. Section IV: Long-term management of the transplant recipient. IV. 6. 1. Cancer risk after renal transplantation. Post-transplant lymphoproliferative disease (PTLD): prevention and treatment. Nephrol Dial Transplant. 2002; 17 Suppl 4: 31-3, 5-6
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16) European best practice guidelines for renal transplantation. Section IV: Long-term management of the transplant recipient. IV. 6. 3. Cancer risk after renal transplantation. Solid organ cancers: prevention and treatment. Nephrol Dial Transplant. 2002; 17 Suppl 4: 32, 4-6
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17) European best practice guidelines for renal transplantation. Section IV: Long-term management of the transplant recipient. IV. 6. 2. Cancer risk after renal transplantation. Skin cancers: prevention and treatment. Nephrol Dial Transplant. 2002; 17 Suppl 4: 31-6
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18) Kasiske BL, Vazquez MA, Harmon WE, et al. Recommendations for the outpatient surveillance of renal transplant recipients. American Society of Transplantation. J Am Soc Nephrol. 2000; 11 Suppl 15: S1-86
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19) Penn I. Evaluation of transplant candidates with pre-existing malignancies. Ann Transplant. 1997; 2: 14-7
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20) Woodle ES, Gupta M, Buell JF, et al. Prostate cancer prior to solid organ transplantation: the Israel Penn International Transplant Tumor Registry experience. Transplant Proc. 2005; 37: 958-9
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21) Holmes RD, Sokol RJ. Epstein-Barr virus and post-transplant lymphoproliferative disease. Pediatr Transplant. 2002; 6: 456-64
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22) Wigle DA, Chaparro C, Humar A, et al. Epstein-Barr virus serology and posttransplant lymphoproliferative disease in lung transplantation. Transplantation. 2001; 72: 1783-6
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23) Walker RC, Marshall WF, Strickler JG, et al. Pretransplantation assessment of the risk of lymphoproliferative disorder. Clin Infect Dis. 1995; 20: 1346-53
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24) Dharnidharka VR, Araya CE. Post-transplant lymphoproliferative disease. Pediatr Nephrol. 2009; 24: 731-6
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25) Caillard S, Dharnidharka V, Agodoa L, et al. Posttransplant lymphoproliferative disorders after renal transplantation in the United States in era of modern immunosuppression. Transplantation. 2005; 80: 1233-43
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26) Hojo M, Morimoto T, Maluccio M, et al. Cyclosporine induces cancer progression by a cell-autonomous mechanism. Nature. 1999; 397: 530-4
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28) Webster AC, Woodroffe RC, Taylor RS, et al. Tacrolimus versus ciclosporin as primary immunosuppression for kidney transplant recipients: meta-analysis and meta-regression of randomised trial data. BMJ. 2005; 331: 810
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29) Sorensen HT, Mellemkjaer L, Nielsen GL, et al. Skin cancers and non-Hodgkin lymphoma among users of systemic glucocorticoids: a population-based cohort study. J Natl Cancer Inst. 2004; 96: 709-11
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33) Opelz G, Dohler B. Lymphomas after solid organ transplantation: a collaborative transplant study report. Am J Transplant. 2004; 4: 222-30
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37) Nashan B. Review of the proliferation inhibitor everolimus. Expert Opin Investig Drugs. 2002; 11: 1845-57
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38) Witzig TE, Geyer SM, Ghobrial I, et al. Phase II trial of single-agent temsirolimus (CCI-779) for relapsed mantle cell lymphoma. J Clin Oncol. 2005; 23: 5347-56
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39) Yee KW, Zeng Z, Konopleva M, et al. Phase I/II study of the mammalian target of rapamycin inhibitor everolimus (RAD001) in patients with relapsed or refractory hematologic malignancies. Clin Cancer Res. 2006; 12: 5165-73
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40) Hudes G, Carducci M, Tomczak P, et al. Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma. N Engl J Med. 2007; 356: 2271-81
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41) Nepomuceno RR, Balatoni CE, Natkunam Y, et al. Rapamycin inhibits the interleukin 10 signal transduction pathway and the growth of Epstein Barr virus B-cell lymphomas. Cancer Res. 2003; 63: 4472-80
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42) Garcia VD, Bonamigo-Filho JS, Neumann J, et al. Rituximab and rapamycin for posttransplant lymphoproliferative disease treatment: report of three cases. Transplant Proc. 2002; 34: 2993-5
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43) Majewski M, Korecka M, Joergensen J, et al. Immunosuppressive TOR kinase inhibitor everolimus (RAD) suppresses growth of cells derived from posttransplant lymphoproliferative disorder at allograft-protecting doses. Transplantation. 2003; 75: 1710-7
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44) Al-Akash SI, Al Makadma AS, Al Omari MG. Rapid response to rituximab in a pediatric liver transplant recipient with post-transplant lymphoproliferative disease and maintenance with sirolimus monotherapy. Pediatr Transplant. 2005; 9: 249-53
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45) Stallone G, Schena A, Infante B, et al. Sirolimus for Kaposi's sarcoma in renal-transplant recipients. N Engl J Med. 2005; 352: 1317-23
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46) Kneteman NM, Oberholzer J, Al Saghier M, et al. Sirolimus-based immunosuppression for liver transplantation in the presence of extended criteria for hepatocellular carcinoma. Liver Transpl. 2004; 10: 1301-11
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47) Kahan BD, Yakupoglu YK, Schoenberg L, et al. Low incidence of malignancy among sirolimus/cyclosporine-treated renal transplant recipients. Transplantation. 2005; 80: 749-58
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48) Schena FP, Pascoe MD, Alberu J, et al. Conversion from calcineurin inhibitors to sirolimus maintenance therapy in renal allograft recipients: 24-month efficacy and safety results from the CONVERT trial. Transplantation. 2009; 87: 233-42
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49) Eisen HJ, Tuzcu EM, Dorent R, et al. Everolimus for the prevention of allograft rejection and vasculopathy in cardiac-transplant recipients. N Engl J Med. 2003; 349: 847-58
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50) Vitko S, Margreiter R, Weimar W, et al. Three-year efficacy and safety results from a study of everolimus versus mycophenolate mofetil in de novo renal transplant patients. Am J Transplant. 2005; 5: 2521-30
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51) Lorber MI, Mulgaonkar S, Butt KM, et al. Everolimus versus mycophenolate mofetil in the prevention of rejection in de novo renal transplant recipients: a 3-year randomized, multicenter, phase III study. Transplantation. 2005; 80: 244-52
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53) Orentas RJ, Schauer DW Jr, Ellis FW, et al. Monitoring and modulation of Epstein-Barr virus loads in pediatric transplant patients. Pediatr Transplant. 2003; 7: 305-14
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57) Penn I. The role of immunosuppression in lymphoma formation. Springer Semin Immunopathol. 1998; 20: 343-55
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58) Pirsch JD, Stratta RJ, Sollinger HW, et al. Treatment of severe Epstein-Barr virus-induced lymphoproliferative syndrome with ganciclovir: two cases after solid organ transplantation. Am J Med. 1989; 86: 241-4
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63) LeBrun CJ, Diehl LF, Abbott KC, et al. Life expectancy benefits of cancer screening in the end-stage renal disease population. Am J Kidney Dis. 2000; 35: 237-43
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