|
1) Donoghue M, Hsieh F, Baronas E, et al. A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9. Circ Res. 2000; 87: E1-9
|
|
|
|
2) Akpinar P, Kuwajima S, Krutzfeldt J, et al. Tmem27: a cleaved and shed plasma membrane protein that stimulates pancreatic beta cell proliferation. Cell Metab. 2005; 2: 385-97
|
|
|
|
|
3) Turner AJ. Exploring the structure and function of zinc metallopeptidases: old enzymes and new discoveries. Biochem Soc Trans. 2003; 31: 723-7
|
|
|
|
|
|
4) Lambert DW, Yarski M, Warner FJ, et al. Tumor necrosis factor-alpha convertase (ADAM17) mediates regulated ectodomain shedding of the severe-acute respiratory syndrome-coronavirus (SARS-CoV) receptor, angiotensin-converting enzyme-2 (ACE2). J Biol Chem. 2005; 280: 30113-9
|
|
|
|
|
|
5) Guy JL, Jackson RM, Acharya KR, et al. Angiotensin-converting enzyme-2 (ACE2): comparative modeling of the active site, specificity requirements, and chloride dependence. Biochemistry. 2003; 42: 13185-92
|
|
|
|
|
|
6) Alenina N, Xu P, Rentzsch B, et al. Genetically altered animal models for Mas and angiotensin- (1-7). Exp Physiol. 2008; 93: 528-37
|
|
|
|
|
|
7) Santos RA, Ferreira AJ, Simoes ESAC. Recent advances in the angiotensin-converting enzyme 2-angiotensin(1-7)-Mas axis. Exp Physiol. 2008; 93: 519-27
|
|
|
|
|
|
8) Crackower MA, Sarao R, Oudit GY, et al. Angiotensin-converting enzyme 2 is an essential regulator of heart function. Nature. 2002; 417: 822-8
|
|
|
|
|
|
9) Gurley SB, Allred A, Le TH, et al. Altered blood pressure responses and normal cardiac phenotype in ACE2-null mice. J Clin Invest. 2006; 116: 2218-25
|
|
|
|
|
|
10) Gurley SB, Coffman TM. Angiotensin-converting enzyme 2 gene targeting studies in mice: mixed messages. Exp Physiol. 2008; 93: 538-42
|
|
|
|
|
|
11) Wong DW, Oudit GY, Reich H, et al. Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury. Am J Pathol. 2007; 171: 438-51
|
|
|
|
|
|
12) Yamamoto K, Ohishi M, Katsuya T, et al. Deletion of angiotensin-converting enzyme 2 accelerates pressure overload-induced cardiac dysfunction by increasing local angiotensin II. Hypertension. 2006; 47: 718-26
|
|
|
|
|
|
13) Zisman LS, Keller RS, Weaver B, et al. Increased angiotensin-(1-7)-forming activity in failing human heart ventricles: evidence for upregulation of the angiotensin-converting enzyme homologue ACE2. Circulation. 2003; 108: 1707-12
|
|
|
|
|
|
14) Yang W, Huang W, Su S, et al. Association study of ACE2 (angiotensin I-converting enzyme 2) gene polymorphisms with coronary heart disease and myocardial infarction in a Chinese Han population. Clin Sci(Lond). 2006; 111: 333-40
|
|
|
|
|
|
15) Kuba K, Imai Y, Rao S, et al. A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury. Nat Med. 2005; 11: 875-9
|
|
|
|
|
|
16) Li W, Moore MJ, Vasilieva N, et al. Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus. Nature. 2003; 426: 450-4
|
|
|
|
|
|
17) Kuba K, Imai Y, Rao S, et al. Lessons from SARS: control of acute lung failure by the SARS receptor ACE2. J Mol Med. 2006; 84: 814-20
|
|
|
|
|
|
18) Ye M, Wysocki J, William J, et al. Glomerular localization and expression of angiotensin-converting enzyme 2 and angiotensin-converting enzyme: implications for albuminuria in diabetes. J Am Soc Nephrol. 2006; 17: 3067-75
|
|
|
|
|
|
19) Oudit GY, Herzenberg AM, Kassiri Z, et al. Loss of angiotensin-converting enzyme-2 leads to the late development of angiotensin II-dependent glomerulosclerosis. Am J Pathol. 2006; 168: 1808-20
|
|
|
|
|
|
20) Lely AT, Hamming I, van Goor H, et al. Renal ACE2 expression in human kidney disease. J Pathol. 2004; 204: 587-93
|
|
|
|
|
|
21) Konoshita T, Wakahara S, Mizuno S, et al. Tissue gene expression of renin-angiotensin system in human type 2 diabetic nephropathy. Diabetes Care. 2006; 29: 848-52
|
|
|
|
|
|
22) Soler MJ, Wysocki J, Ye M, et al. ACE2 inhibition worsens glomerular injury in association with increased ACE expression in streptozotocin-induced diabetic mice. Kidney Int. 2007; 72: 614-23
|
|
|
|
|
|
23) Zhang H, Wada J, Hida K, et al. Collectrin, a collecting duct-specific transmembrane glycoprotein, is a novel homolog of ACE2 and is developmentally regulated in embryonic kidneys. J Biol Chem. 2001; 276: 17132-9
|
|
|
|
|
|
24) Danilczyk U, Sarao R, Remy C, et al. Essential role for collectrin in renal amino acid transport. Nature. 2006; 444: 1088-91
|
|
|
|
|
|
25) Malakauskas SM, Quan H, Fields TA, et al. Aminoaciduria and altered renal expression of luminal amino acid transporters in mice lacking novel gene collectrin. Am J Physiol. Renal Physiol. 2007; 292: F533-44
|
|
|
|
|
|
26) Fukui K, Yang Q, Cao Y, et al. The HNF-1 target collectrin controls insulin exocytosis by SNARE complex formation. Cell Metab. 2005; 2: 373-84
|
|
|
|
|
|
27) Zhang Y, Wada J, Yasuhara A, et al. The role for HNF-1beta-targeted collectrin in maintenance of primary cilia and cell polarity in collecting duct cells. PLoS ONE. 2007; 2: e414
|
|
|
|
|
|
28) Camargo SM, Singer D, Makrides V, et al. Tissue-specific amino acid transporter partners ACE2 and collectrin differentially interact with hartnup mutations. Gastroenterology. 2009; 136: 872-82
|
|
|
|
|
|
29) Kowalczuk S, Broer A, Tietze N, et al. A protein complex in the brush-border membrane explains a hartnup disorder allele. FASEB J. 2008; 22: 2880-7
|
|
|
|
|
|
30) Yasuhara A, Wada J, Malakauskas SM, et al. Collectrin is involved in the development of salt-sensitive hypertension by facilitating the membrane trafficking of apical membrane proteins via interaction with soluble N-ethylmaleiamide-sensitive factor attachment protein receptor complex. Circulation. 2008; 118: 2146- 55
|
|
|
|
|
|
31) Malakauskas SM, Kourany WM, Zhang XY, et al. Increased insulin sensitivity in mice lacking collectrin, a downstream target of HNF-1{alpha}. Mol Endocrinol. 2009; 23: 881-92
|
|
|
|
|