1) 徳永勝人. ヴィレンドルフ賞歴代受賞者の業績と想い出. 肥満研究. 2007; 13: 117-21
|
|
|
2) 杉原 甫, 戸田修二, 渡辺恵子, 他. 肥満についての, 新しい細胞生物学的分類の提唱. 肥満研究. 2002; 8: 125-30
|
|
|
3) Sakai T, Sakaue H, Nakamura T, et al. Skp2 controls adipocyte proliferation during the development of obesity. J Biol Chem. 2007; 282: 2038-46
|
|
|
4) Spalding KL, Arner E, Westermark PO, et al. Dynamics of fat cell turnover in humans. Nature. 2008; 453: 783-7
|
|
|
5) http://news.bbc.co.uk/2/hi/health/7378349.stm
|
|
|
6) http://www.mext.go.jp/b_menu/toukei/001/index03.htm
|
|
|
7) http://healthyamericans.org/reports/obesity2007/Obesity2007Report.pdf
|
|
|
8) Takashima Y, Era T, Nakao K, et al. Neuro-epithelial cells supply an initial transient wave of MSC differentiation. Cell. 2007; 129: 1377-88
|
|
|
9) Hausman DB, DiGirolamo M, Bartness TJ, et al. The biology of white adipocyte proliferation. Obes Rev. 2001; 2: 239-54
|
|
|
10) Rosen ED, MacDougald OA. Adipocyte differ-entiation from the inside out. Nat Rev Mol Cell Biol. 2006; 7: 885-96
|
|
|
11) Bost F, Aouadi M, Caron L, et al. The extra-cellular signal-regulated kinase isoform ERK1 is specifically required for in vitro and in vivo adipogenesis. Diabetes. 2005; 54: 402-11
|
|
|
12) Dani C. Embryonic stem cell-derived adipo-genesis. Cells Tissues Organs. 1999; 165: 173-80
|
|
|
13) Loftus TM, Kuhajda FP, Lane MD. Insulin depletion leads to adipose-specific cell death in obese but not lean mice. Proc Natl Acad Sci U S A. 1998; 95: 14168-72
|
|
|
14) Cinti S, Mitchell G, Obin MS. Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans. J Lipid Res. 2005; 46: 2347-55
|
|
|
15) Kubota N, Terauchi Y, Miki H, et al. PPAR gamma mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance. Mol Cell. 1999; 4: 597-609
|
|
|
16) Walkey CJ, Spiegelman BM. A functional PPARgamma ligand binding domain is not required for adipogenesis. J Biol Chem. 2008; 283: 24290-4
|
|
|
17) Rosen ED, Spiegelman BM. Molecular regulation of adipogenesis. Annu Rev Cell Dev Biol. 2000; 16: 145-71
|
|
|
18) Imai T, Takakuma R, Marchand S, et al. Peroxisome proliferator-activated receptor gamma is required in mature white and brown adipocytes for their survival in the mouse. Proc Natl Acad Sci U S A. 2004; 101: 4543-7
|
|
|
19) He W, Barak Y, Hevener A, et al. Adipose-specific peroxisome proliferator-activated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle. Proc Natl Acad Sci U S A. 2003; 100: 15712-7
|
|
|
20) Wang ND, Finegold MJ, Bradly A, et al. Impaired energy homeostasis in C/EBP alpha knockout mice. Science. 1995; 269: 1108-12
|
|
|
21) Rosen ED, Hsu CH, Wang X, et al. C/EBPalpha induces adipogenesis through PPARgamma: a unified pathway. Genes Dev. 2002; 16: 22-6
|
|
|
22) Wu Z, Rosen ED, Brun R, et al. Cross-regulation of C/EBP alpha and PPAR gamma controls the transcriptional pathway of adipogenesis and insulin sensitivity. Mol Cell. 1999; 3: 151-8
|
|
|
23) Porse BT, Pedersen TA, Xu X, et al. E2F repression by C/EBPalpha is required for adipogenesis and granulopoiesis in vivo. Cell. 2001; 107: 247-58
|
|
|
24) Tanaka T, Yoshida N, Kishimoto T, et al. Defective adipocyte differentiation in mice lacking the C/EBPbeta and/or C/EBPdelta gene. EMBO J. 1997; 16: 7432-43
|
|
|
25) Shimano H, Shimomura I, Hammer RE, et al. Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene. J Clin Invest. 1997; 100: 2115-24
|
|
|
26) Banerjee SS, Feinberg MW, Watanabe M, et al. The Kruppel-like factor KLF2 inhibits peroxisome proliferator-activated receptor-gamma expression and adipogenesis. J Biol Chem. 2003; 278: 2581-4
|
|
|
27) Sue N, Jack BH, Eaton SA, et al. Targeted disruption of the basic Kruppel-like factor gene (Klf3) reveals a role in adipogenesis. Mol Cell Biol. 2008; 28: 3967-78
|
|
|
28) Li D, Yea S, Li S, Chen Z, et al. Kruppel-like factor-6 promotes preadipocyte differentiation through histone deacetylase 3-dependent repression of DLK1. J Biol Chem. 2005; 280: 26941-52
|
|
|
29) Kawamura Y, Tanaka Y, Kawamori R, et al. Overexpression of Kruppel-like factor 7 regulates adipocytokine gene expressions in human adipocytes and inhibits glucose-induced insulin secretion in pancreatic beta-cell line. Mol Endocrinol. 2006; 20: 844-56
|
|
|
30) LinksBirsoy K, Chen Z, Friedman J. Trans-criptional regulation of adipogenesis by KLF4. Cell Metab. 2008; 7: 339-47
|
|
|
31) Oishi Y, Manabe I, Tobe K, et al. Kruppel-like transcription factor KLF5 is a key regulator of adipocyte differentiation. Cell Metab. 2005; 1: 27-39
|
|
|
32) Mori T, Sakaue H, Iguchi H, et al. Role of Kruppel-like factor 15 (KLF15) in transcriptional regulation of adipogenesis. J Biol Chem. 2005; 280: 12867-75
|
|
|
33) Feige JN, Auwerx J. Transcriptional coregulators in the control of energy homeostasis. Trends Cell Biol. 2007; 17: 292-301
|
|
|
34) Fajas L, Landsberg RL, Huss-Garcia Y, et al. E2F regulates adipocyte differentiation. Dev Cell. 2002; 3: 39-49
|
|
|
35) Abella A, Dubus P, Malumbres M, et al. Cdk4 promotes adipogenesis through PPARgamma activation. Cell Metab. 2005; 2: 239-49
|
|
|
36) Sarruf DA, Iankova I, Abella A, et al. Cyclin D3 promotes adipogenesis through activation of peroxisome proliferators-activated receptor gamma. Mol Cell Biol. 2005; 25: 9985-95
|
|
|