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1) Shimano H. SREBP-1c and TFE3, energy transcription factors that regulate hepatic insulin signaling. J Mol Med. 2007; 85: 437-44
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2) Nakagawa Y, Shimano H, Yoshikawa T, et al. TFE3 transcriptionally activates hepatic IRS-2, participates in insulin-signaling and, ameliorates diabetes. Nat Med. 2006; 12: 107-13
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3) Shimano H, Yahagi N, Amemiya-Kudo M, et al. Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes. J Biol Chem. 1999; 274: 35832-9
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4) Shimano H. Sterol regulatory element-binding proteins (SREBPs): transcriptional regulators of lipid synthetic genes. Prog Lipid Res. 2001; 40: 439-52
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5) Matsuzaka T, Shimano H, Yahagi N, et al. Cloning and characterization of a mammalian fatty acyl-CoA elongase as a lipogenic enzyme regulated by SREBPs. J Lipid Res. 2002; 43: 911-20
PubMed
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6) Moon YA, Shah NA, Mohapatra S, et al. Identification of a mammalian long chain fatty acyl elongase regulated by sterol regulatory element-binding proteins. J Biol Chem. 2001; 276: 45358-66
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7) Nagarajan R, Le N, Mahoney H, et al. Deciphering peripheral nerve myelination by using Schwann cell expression profiling. Proc Natl Acad Sci U S A. 2002; 99: 8998-9003
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8) Kumadaki S, Matsuzaka T, Kato T, et al. Mouse Elovl-6 promoter is an SREBP target. Biochem Biophys Res Commun. 2008; 368: 261-6
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9) Matsuzaka T, Shimano H, Yahagi N, et al. Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance. Nat Med. 2007; 13: 1193-202
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10) Ide T, Shimano H, Yahagi N, et al. Lipid synthetic transcription factors SREBPs suppress IRS-2-mediated insulin signaling in the liver. Nat Cell Biol. 2004; 6: 351-7
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11) Samuel VT, Liu ZX, Wang A, et al. Inhibition of protein kinase Cepsilon prevents hepatic insulin resistance in nonalcoholic fatty liver disease. J Clin Invest. 2007; 117: 739-45
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12) Bruce CR, Febbraio MA. It's what you do with the fat that matters. Nat Med. 2007; 13: 1137-8
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13) Takahashi A, Motomura K, Kato T, et al. Transgenic mice overexpressing nuclear SREBP-1c in pancreatic beta-cells. Diabetes. 2005; 54: 492-9
PubMed
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14) Kato T, Shimano H, Yamamoto T, et al. Granuphilin is activated by SREBP-1c and involved in impaired insulin secretion in diabetic mice. Cell Metab. 2006; 4: 143-54
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15) Inoue N, Shimano H, Nakakuki M, et al. Lipid synthetic transcription factor SREBP-1a activates p21WAF1/CIP1, a universal cyclin-dependent kinase inhibitor. Mol Cell Biol. 2005; 25: 8938-47
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16) Ishigaki N, Yamamoto T, Shimizu Y, et al. Involvement of glomerular SREBP-1c in diabetic nephropathy. Biochem Biophys Res Commun. 2007; 364: 502-8
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