|
1) Backert S, Selbach M. Role of type IV secretion in Helicobacter pylori pathogenesis. Cell Microbiol. 2008. In press
|
|
|
|
|
2) Hatakeyama M. Oncogenic mechanisms of the Helicobacter pylori CagA protein. Nat Rev Cancer. 2004; 9: 688-94
|
|
|
|
|
|
3) Naito M, Yamazaki T, Tsutsumi R, et al. Influence of EPIYA-repeat polymorphism on the phosphorylation-dependent biological activity of Helicobacter pylori CagA. Gastroenterology. 2006; 130: 1181-90
|
|
|
|
|
4) Higashi H, Tsutsumi R, Muto S, et al. SHP-2 tyrosine phosphatase as an intracellular target of Helicobacter pylori CagA protein. Science. 2002; 295: 683-6
|
|
|
|
|
5) Tsutsumi R, Takahashi A, Azuma T, et al. FAK is a substrate and downstream effector of SHP-2 complexed with Helicobacter pylori CagA. Mol Cell Biol. 2006; 26: 261-76
|
|
|
|
|
|
6) Higashi H, Nakaya A, Tsutsumi R, et al. Helicobacter pylori CagA provokes Ras-independent morphogenetic response through SHP-2 recruitment and activation. J Biol Chem. 2004; 279: 17205-16
|
|
|
|
|
|
7) Neel BG, Gu H, Pao L. The ‘Shp'ing news: SH2 domain-containing tyrosine phosphatase in cell signaling. Trends Biochem Sci. 2003; 28: 284-93
|
|
|
|
|
|
8) Tartaglia M, Mehler EL, Goldberg R, et al. Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome. Nat Genet. 2001; 29: 465-8
|
|
|
|
|
|
9) Tartaglia M, Niemeyer CM, Fragale A, et al. Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia. Nat Genet. 2003; 34: 148-50
|
|
|
|
|
|
10) Amieva MR, Vogelmann R, Covacci A, et al. Disruption of the epithelial apical-junctional complex by Helicobacter pylori CagA. Science. 2003; 300: 1430-4
|
|
|
|
|
|
11) Saadat I, Higashi H, Obuse C, et al. Helicobacter pylori CagA targets PAR-1/MARK kinase to disrupt epithelial cell polarity. Nature. 2007; 447: 330-3
|
|
|
|
|
|
12) Suzuki A, Ohno S. The PAR-aPKC system: lessons in polarity. J Cell Sci. 2006; 119: 979-87
|
|
|
|
|
|
13) Ren S, Higashi H, Lu H, et al. Structural basis and functional consequence of Helicobacter pylori CagA multimerization in Cells. J Biol Chem. 2006; 281: 32344-52
|
|
|
|
|
|
14) Ohnishi N, Yuasa H, Tanaka S, et al. Transgenic expression of Helicobacter pylori CagA induces gastrointestinal and hematopoietic neoplasms in mouse. Proc Natl Acad Sci U S A. 2008; 105: 1003-8
|
|
|
|
|
|
15) Matsumoto Y, Marusawa H, Kinoshita K, et al. Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium. Nat Med. 2007; 13: 470-6
|
|
|
|
|
|
16) Muramatsu M, Nagaoka H, Shinkura R, et al. Discovery of activation-induced cytidine deaminase, the engraver of antibody memory. Adv Immunol. 2007; 94: 1-36
|
|
|
|
|
|
17) Okazaki IM, Hiai H, Kakazu N, et al. Constitutive expression of AID leads to tumorigenesis. J Exp Med. 2003; 197: 1173-81
|
|
|
|
|
|
18) Endo Y, Marusawa H, Kinoshita K, et al. Expression of activation-induced cytidine deaminase in human hepatocytes via NF-κB signaling. Oncogene. 2007; 26: 5587-95
|
|
|
|
|
|
19) Houghton J, Stoicov C, Nomura S, et al. Gastric cancer originating from bone marrow-derived cells. Science. 2004; 306: 1568-71
|
|
|
|
|