|
1) Grant SFA, Thorleifsson G, Reynisdottir I, et al. Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet. 2006; 38: 320-3
|
|
|
|
2) Reynisdottir I, Thorleifsson G, Benediktsson R, et al. Localization of a susceptibility gene for type 2 diabetes to chromosome 5q34-q35. 2. Am J Hum Genet. 2003; 73: 323-35
|
|
|
|
|
|
3) Duggirala R, Blangero J, Almasy L, et al. Linkage of type 2 diabetes mellitus and age at onset a genetic location on chromosome 10q in Mexican Americans. Am J Hum Genet. 1999; 64: 1127- 40
|
|
|
|
|
|
4) Scott L, Bonnycastle LL, Willer CJ, et al. Association of transcription factor 7-like 2 (TCF7L2) variants with type 2 diabetes in a Finnish sample. Diabetes. 2006; 55: 2649-53
|
|
|
|
|
|
5) Damcott CM, Pollin TI, Reinhart LJ, et al. Polymorphisms in the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in the Amish. Diabetes. 2006; 55: 2654- 9
|
|
|
|
|
|
6) Groves CJ, Zeggini E, Minton J, et al. Association analysis of 6, 736 U. K. subjects provides replication and confirms TCF7L2 as a type 2 diabetes susceptibility gene with a substantial effect on individual risk. Diabetes. 2006; 55: 2640-4
|
|
|
|
|
|
7) Cauchi S, Meyre D, Dina C, et al. Transcription factor TCF7L2 genetic study in the French population. Diabetes. 55; 2006; 2903-8
|
|
|
|
|
|
8) Marzi C, Huth C, Kolz M, et al. Variants of the transcription factor 7-like 2 gene (TCF7L2) are strongly associated with type 2 diabetes but not with the metabolic syndrome in the Monica/kora surveys. Horm Metab Res. 2007; 39: 46-52
|
|
|
|
|
|
9) Melzer D, Murray A, Hurst AJ, et al. Effects of the diabetes linked TCF7L2 polymorphism in a representative older population. BMC Med. 2006; 4: 34
|
|
|
|
|
|
10) Van Vliet-Ostaptchouk JV, Shiri-Sverdlov R, Zhernakova A, et al. Association of variants of transcription factor 7-like 2 (TCF7L2) with susceptibility to type 2 diabetes in the Dutch breda cohort. Diabetologia. 2007; 50: 59-62
|
|
|
|
|
|
11) Saxena R, Gianniny L, Burtt NP, et al. Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals. Diabetes. 2006; 55: 2890-5
|
|
|
|
|
|
12) Chandak GR, Janipalli CS, Bhaskar S, et al. Common variants in the TCF7L2 gene strongly associated with type 2 diabetes mellitus in the Indian population. Diabetologia. 2007; 50: 63-7
|
|
|
|
|
|
13) Lehman DM, Hunt KJ, Leach RJ, et al. Haplotypes of transcription factor 7-like 2 (TCF7L2) gene and its upstream region are associated with type 2 diabetes and age of onset in Mexican Americans. Diabetes. 2007; 56: 389-93
|
|
|
|
|
|
14) Horikoshi M, Hara K, Ito C, et al. A genetic variation of the transcription factor 7-like 2 gene is associated with risk of type 2 diabetes in the Japanese population. Diabetologia. 2007; 50: 747-51
|
|
|
|
|
|
15) Hayashi T, Iwamoto Y, Kaku K, et al. Replication study for the association of TCF7L2 with susceptibility to type 2 diabetes in a Japanese population. Diabetologia. 2007; 50: 980-4
|
|
|
|
|
|
16) Mori Y, Otabe S, Dina C, et al. Genome-wide search for type 2 diabetes in Japanese affected sib-pairs confirms susceptibility genes on 3q, 15q, and 20q and identifies two new candidate Loci on 7p and 11p. Diabetes. 2002; 51: 1247- 55
|
|
|
|
|
|
17) Iwasaki N, Cox NJ, Wang YQ, et al. Mapping genes influencing type 2 diabetes risk and BMI in Japanese subjects. Diabetes. 2003; 52: 209-13
|
|
|
|
|
|
18) Nawata H, Shirasawa S, Nakashima N, et al. Genome-wide linkage analysis of type 2 diabetes mellitus reconfirms the susceptibility locus on 11p13-p12 in Japanese. J Hum Genet. 2004; 49: 629-34
|
|
|
|
|
19) Florez JC, Jablonski K, Bayley N, et al. TCF7L2 polymorphisms and progression to diabetes in the diabetes prevention program. N Engl J Med. 2006; 355: 241-50
|
|
|
|
|
|
20) Lyssenko V, Lupi R, Marchetti P, et al. Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes. J Clin Invest. 2007; 117: 2155-63
|
|
|
|
|
|
21) Yi F, Brubaker PL, Jin T. TCF-4 mediates cell type-specific regulation of proglucagon gene expression by β-catenin and glycogen synthase kinase-3β. J Biol Chem. 2005; 280: 1457-64
|
|
|
|
|
|
22) Zeggini E, McCarthy MI. TCF7L2: the biggest story in diabetes genetics since HLA？ Diabetologia. 2007; 50: 1-4
|
|
|
|
|
|
23) Sladek R, Rocheleau G, Rung J, et al. A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature. 2007; 445: 881-5
|
|
|
|
|
|
24) Scott LJ, Mohlke KL, Bonnycastle LL, et al. A genome-wide association study of type 2 diabetes in finns detects multiple susceptibility variants. Science. 2007; 616: 1341-5
|
|
|
|
|
|
25) Salonen JY, Uimari P, Atlto JM, et al. Type 2 diabetes whole-genome association study in four populations: the DiaGen consortium. Am J Hum Genet. 2007; 81: 338-45
|
|
|
|
|