|
1）Pilette C, Nouri-Aria KT, Jacobson MR, et al. Grass pollen immunotherapy induces an allergen-specific IgA2 antibody response associated with mucosal TGF-β expression. J Immunol. 2007; 178: 4658-66
|
|
|
|
2）Francis JN, Till SJ, Durham SR. Induction of IL-10＋CD4＋CD25＋ T cells by grass pollen immunotherapy. J Allergy Clin Immunol. 2003; 111: 1255-61
|
|
|
|
|
3）大久保公裕, 他. 花粉症のQOLからみた各種治療法評価と新しい治療法開発の基礎的研究. 平成15年度 厚生労働科学研究成果報告; 文献番号200300659A
|
|
|
|
|
|
4）Jutel M, Akdis M, Budak F, et al. IL-10 and TGF-beta cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy. Eur J Immunol. 2003; 33: 1205-14
|
|
|
|
|
|
5）Takagi H, Hiroi T, Yang L, et al. A rice-based edible vaccine expressing multiple T cell epitopes induced oral tolerance for inhibition of Th2-mediated IgE responses. Proc Natl Acad Sci USA. 2005; 102: 17525-30
|
|
|
|
|
|
6）Hiroi T, Takaiwa F. Peptide immunotherapy for allergic disease using a rice-based edible vaccine. Curr Opin Allergy Clin Immunol. 2006; 6: 455-60
|
|
|
|
|
|
7）Jain VV, Businga TR, Kitagaki K, et al. Mucosal immunotherapy with CpG oligodeoxynucleotides reverses a murine model of chronic asthma induced by repeated antigen exposure. Am J Physiol Lung Cell Mol Physiol. 2003; 285: L1137-46
|
|
|
|
|
|
8）Toda M, Sato H, Takebe Y, et al. Inhibition of immunoglobulin E response to Japanese cedar pollen allergen (Cry j 1) in mice by DNA immunization: different outcomes on the plasmid DNA inoculation method. Immunology. 2000; 99: 179-86
|
|
|
|
|
|
9）Santeliz JV, Van Nest G, Traquina P, et al. Amb a 1-linked CpG oligodeoxynucleotides reverse established airway hyperresponsiveness in a murine model of asthma. J Allergy Clin Immunol. 2002; 109: 455-62
|
|
|
|
|
|
10）Marshall JD, Abtahi S, Eiden JJ, et al. Immunostimulatory sequence DNA linked to the Amb a 1 allergen promotes T(H)1 cytokine expression while downregulating T(H)2 cytokine expression in PBMCs from human patients with ragweed allergy. J Allergy Clin Immunol. 2001; 108: 191-7
|
|
|
|
|
|
11）Erb KJ, Holloway JW, Sobeck A, et al. Infection of mice with Mycobacterium bovis-Bacillus Calmette-Guerin(BCG) suppresses allergen-induced airway eosinophilia. J Exp Med. 1998; 187: 561-9
|
|
|
|
|
|
12）Zuany-Amorim C, Manlius C, Trifilieff A, et al. Long-term protective and antigen-specific effect of heat-killed Mycobacterium vaccae in a murine model of allergic pulmonary inflammation. J Immunol. 2002; 169: 1492-9
|
|
|
|
|
|
13）Suto A, Nakajima H, Hirose K, et al. Interleukin 21 prevents antigen-induced IgE production by inhibiting germ line Cε transcription of IL-4 stimulated B cells. Blood. 2002; 100: 4565-73
|
|
|
|
|
|
14）Harada M, Koyanagi KM, Watarai H, et al. IL-21-induced Bε cell apoptosis mediated by natural killer T cells suppresses IgE responses. J Exp Med. 2006; 203: 2929-37
|
|
|
|
|
|
15）Toda M, Kasai M, Hosokawa H, et al. DNA vaccine using invariant chain gene for delivery of CD4＋ T cell epitope peptide derived from Japanese cedar pollen allergen inhibits allergen-specific IgE response. Eur J Immunol. 2002; 32: 1631-9
|
|
|
|
|
|
16）Suzuki M, Ohta N, Min WP, et al. Immunotherapy with CpG DNA conjugated with T-cell epitope peptide of an allergenic Cry j 2 protein is useful for control of allergic conditions in mice. Int Immunopharmacol. 2007; 7: 46-54
|
|
|
|
|
|
17）Faria AMC, Weiner HL. Oral tolerance. Immunol Rev. 2005; 206: 232-59
|
|
|
|
|
|
18）Mahnke K, Qian Y, Knop J, et al. Induction of CD4＋/CD25＋ regulatory T cells by targeting of antigens to immature dendritic cells. Blood. 2003; 101: 4862-9
|
|
|
|
|
|
19）Annacker O, Coombes JL, Malmstrom V, et al. Essential role for CD103 in the T cell-mediated regulation of experimental colitis. J Exp Med. 2005; 202: 1051-61
|
|
|
|
|
|
20）Viney JL, Mowat AM, O'Malley JM, et al. Expanding dendritic cells in vivo enhances the induction of oral tolerance. J Immunol. 1998; 160: 5815-25
|
|
|
|
|
|
21）Nagatani K, Dohi M, To Y, et al. Splenic dendritic cells induced by oral antigen administration are important for the transfer of oral tolerance in an experimental model of asthma. J Immunol. 2006; 176: 1481-9
|
|
|
|
|
|
22）Read S, Malmstrom V, Powrie F. Cytotoxic T Lymphocyte-associated Antigen 4 plays an essential role in the function of CD25＋CD4＋ regulatory cells that control intestinal inflammation. J Exp Med. 2000; 192: 295-302
|
|
|
|
|
|
23）Shimizu J, Yamazaki S, Takahashi, T, et al. Stimulation of CD25＋CD4＋ regulatory T cells through GITR breaks immunological self-tolerance. Nat Immunol. 2002; 3: 135-42
|
|
|
|
|
|
24）Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science. 2003; 299: 1057-61
|
|
|
|
|
|
25）Nakamura K, Kitani A, Strober W. Cell contact-dependent immunosuppression by CD4＋CD25＋ regulatory T cells is mediated by cell surface-bound transforming growth factor β. J Exp Med. 2001; 194: 629-44
|
|
|
|
|
|
26）Ostroukhova M, Seguin-Devaux C, Oriss TB, et al. Tolerance induced by inhaled antigen involves CD4＋ T cells expressing membrane-bound TGF-β and FOXP3. J Clin Invest. 2004; 114: 28-38
|
|
|
|
|
|
27）Sun JB, Czerkinsky C, Holmgren J. Sublingual ‘Oral Tolerance' induction with antigen conjugated cholera toxin B subunit generates regulatory T cells that induce apoptosis and depletion of effector T cells. J Scad Immunol. 2007; 66: 278-86
|
|
|
|
|
|
28）Chung Y, Lee SH, Kim DH, et al. Complementary role of CD4＋CD25＋ regulatory T cells and TGF-β in oral tolerance. J Leukocyte Biol. 2005; 77: 906-13
|
|
|
|
|
|
29）Kuwata H, Watanabe Y, Miyoshi H, et al. IL-10 inducible Bcl-3 negatively regulates LPS-induced TNF-α production in macrophages. Blood. 2003; 102: 4123-9
|
|
|
|
|
|
30）Hirotani T, Lee PY, Kuwata H, et al. The nuclear IκB protein IκBNS selectively inhibits lipopolysaccharide-indused IL-6 production in macrophages of the colonic lamina propria. J Immunol. 2005; 174: 3650-7
|
|
|
|
|