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1) Dyspnea. Mechanisms, Assessment, and Management: A Consensus Statement. Am J Respir Crit Care Med. 1999; 159: 321-40
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2) Mahler DA, Harver A, Lentine T, et al. Descriptors of breathlessness in cardiorespiratory diseases. Am J Respir Crit Care Med. 1996; 154: 1357-63
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3) O'Donnell DE, Bertley JC, Chau LK, et al. Qualitative aspects of exertional breathlessness in chronic airflow limitation: pathophysiologic mechanisms. Am J Respir Crit Care Med. 1997; 155: 109-15
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4) O'Donnell DE, Laveneziana P. Physiology and consequences of lung hyperinflation in COPD. Eur Respir Rev. 2006; 15: 61-7
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5) O'Donnell DE, Revill SM, Webb KA. Dynamic hyperinflation and exercise intolerance in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2001; 164: 770-7
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6) O'Donnell DE, Laveneziana P. The clinical importance of dynamic lung hyperinflation in COPD. COPD. 2006; 3: 219-32
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7) Sinderby C, Spahija J, Beck J, et al. Diaphragm activation during exercise in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2001; 163: 1637-41
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8) Leblane P, Summers E, Inman MD, et al. Inspiratory muscles during exercise. A problem of supply and demand. J Appl Physiol. 1988; 64: 283-2489
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9) O'Donnell DE, D'Arsigny C, Fitzpatrick M, et al. Exercise hypercapnia in advanced chronic obstructive pulmonary disease: the role of lung hyperinflation. Am J Respir Crit Care Med. 2002; 166: 663-8
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10) Stark-Leyva KN, Beck KC, Johnson BD. Influence of expiratory loading and hyperinflation on cardiac output during exercise. J Appl Physiol. 2004; 96: 1920-7
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11) O'Donnell DE, et al. Pathophysiology of dyspnea in chronic obstructive pulmonary disease. Proc Am Thorac Soc. 2007; 4: 145-68
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12) Marin JM, Carrizo SJ, Gascon M, et al. Inspiratory capacity, dynamic hyperinflation, breathlessness, and exercise performance during the 6-minute-walk test in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2001; 3: 1395-9
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13) O'Donnell DE, Voduc N, Fitzpatrick M, et al. Effect of salmeterol on the ventilatory response to exercise in chronic obstructive pulmonary disease. Eur Respir J. 2004; 24: 86-94
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14) O'Donnell DE, Webb KA. The effects of tiotropium on ventilatory mechanics during exercise in COPD. Am J Respir Crit Care Med. 2005; 2: A494
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15) Ingenito EP, Loring SH, Moy ML, et al. Physiological characterization of variability in response to lung volume reduction surgery. J Appl Physiol. 2003; 94: 20-30
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16) O'Donnell DE, Sanii R, Younes M. Improvement in exercise endurance in patients with chronic airflow limitation using CPAP. Am Rev Respir Dis. 1988; 138: 1510-4
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17) Keilty SE, Ponte J, Fleming TA, et al. Effect of inspiratory pressure support on exercise tolerance and breathlessness in patients with severe stable chronic obstructive pulmonary disease. Thorax. 1994; 49: 990-4
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18) Bianchi R, Gigliotti F, Romagnoli I, et al. Chest wall kinematics and breathlessness during pursed-lip breathing in patients with COPD. Chest. 2004; 125: 459-65
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19) O'Donnell DE, Bain DJ, Webb KA. Factors contributing to relief of exertional breathlessness during hyperoxia in chronic airflow limitation. Am J Respir Crit Care Med. 1997; 155: 530-5
PubMed
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