|
1) Kriz W, Gretz N, Lemley KV. Progression of glomerular diseases: is the podocyte the culprit？ Kidney Int. 1998; 54: 687-97
|
|
|
|
2) Rodewald R, Karnovsky MJ. Porous substructure of the glomerular slit diaphragm in the rat and mouse. J Cell Biol. 1974; 60: 423-33
|
|
|
|
|
|
3) Kestila M, Lenkkeri U, Mannikko M, et al. Positionally cloned gene for a novel glomerular protein?nephrin?is mutated in congenital nephrotic syndrome. Mol Cell. 1998; 1: 575-82
|
|
|
|
|
|
4) Wartiovaara J, Ofverstedt LG, Khoshnoodi J, et al. Nephrin strands contribute to a porous slit diaphragm scaffold as revealed by electron tomography. J Clin Invest. 2004; 114: 1475-83
|
|
|
|
|
|
5) Putaala H, Soininen R, Kilpelainen P, et al. The murine nephrin gene is specifically expressed in kidney, brain and pancreas: inactivation of the gene leads to massive proteinuria and neonatal death. Hum Mol Genet. 2001; 10: 1-8
|
|
|
|
|
|
6) Wernerson A, Duner F, Pettersson E, et al. Altered ultrastructural distribution of nephrin in minimal change nephrotic syndrome. Nephrol Dial Transplant. 2003; 18: 70-6
|
|
|
|
|
|
7) Furness PN, Hall LL, Shaw JA, et al. Glomerular expression of nephrin is decreased in acquired human nephrotic syndrome. Nephrol Dial Transplant. 1999; 14: 1234-7
|
|
|
|
|
|
8) Doublier S, Ruotsalainen V, Salvidio G, et al. Nephrin redistribution on podocytes is a potential mechanism for proteinuria in patients with primary acquired nephrotic syndrome. Am J Pathol. 2001; 158: 1723-31
|
|
|
|
|
|
9) Huh W, Kim DJ, Kim MK, et al. Expression of nephrin in acquired human glomerular disease. Nephrol Dial Transplant. 2002; 17: 478-84
|
|
|
|
|
|
10) Wilson JG, Roth CB, Warkany J. An analysis of the syndrome of malformations induced by maternal vitamin A deficiency. Effects of restoration of vitamin A at various times during gestation. Am J Anat. 1953; 92: 189-217
|
|
|
|
|
|
11) Lelievre-Pegorier M, Vilar J, Ferrier ML, et al. Mild vitamin A deficiency leads to inborn nephron deficit in the rat. Kidney Int. 1998; 54: 1455-62
|
|
|
|
|
|
12) Suzuki A, Ito T, Imai E, et al. Retinoids regulate the repairing process of the podocytes in puromycin aminonucleoside-induced nephrotic rats. J Am Soc Nephrol. 2003; 14: 981-91
|
|
|
|
|
|
13) Yamauchi K, Takano Y, Kasai A, et al. Screening and identification of substances that regulate nephrin gene expression using engineered reporter podocytes. Kidney Int. 2006; 70: 892-900
|
|
|
|
|
|
14) Vaughan MR, Pippin JW, Griffin SV, et al. ATRA induces podocyte differentiation and alters nephrin and podocin expression in vitro and in vivo. Kidney Int. 2005; 68: 133-44
|
|
|
|
|
|
15) Dusso AS, Brown AJ, Slatopolsky E. Vitamin D. Am J Physiol Renal Physiol. 2005; 289: F8-28
|
|
|
|
|
|
16) Migliori M, Giovannini L, Panichi V, et al. Treatment with 1, 25-dihydroxyvitamin D3 preserves glomerular slit diaphragm-associated protein expression in experimental glomeru-lonephritis. Int J Immunopathol Pharmacol. 2005; 18: 779-90
|
|
|
|
|
|
17) Takano Y, Yamauchi K, Hiramatsu N, et al. Recovery and maintenance of nephrin expression in cultured podocytes and identification of HGF as a repressor of nephrin. Am J Physiol Renal Physiol. 2007; 292: F1573-82
|
|
|
|
|
|
18) Kasuga H, Hosogane N, Matsuoka K, et al. Characterization of transgenic rats constitutively expressing vitamin D-24-hydroxylase gene. Biochem Biophys Res Commun. 2002; 297: 1332-8
|
|
|
|
|
|
19) Levin A, Bakris GL, Molitch M, et al. Prevalence of abnormal serum vitamin D, PTH, calcium, and phosphorus in patients with chronic kidney disease: results of the study to evaluate early kidney disease. Kidney Int. 2007; 71: 31-8
|
|
|
|
|
|
20) Kota BP, Huang TH, Roufogalis BD. An overview on biological mechanisms of PPARs. Pharmacol Res. 2005; 51: 85-94
|
|
|
|
|
|
21) Berger J, Moller DE. The mechanisms of action of PPARs. Annu Rev Med. 2002; 53: 409-35
|
|
|
|
|
|
22) Kiec-Wilk B, Dembinska-Kiec A, Olszanecka A, et al. The selected pathophysiological aspects of PPARs activation. J Physiol Pharmacol. 2005; 56: 149-62
|
|
|
|
|
|
23) Ren S, Xin C, Beck KF, et al. PPARalpha activation upregulates nephrin expression in human embryonic kidney epithelial cells and podocytes by a dual mechanism. Biochem Biophys Res Commun. 2005; 338: 1818-24
|
|
|
|
|
|
24) Benigni A, Zoja C, Tomasoni S, et al. Transcriptional regulation of nephrin gene by peroxisome proliferator-activated receptor-gamma agonist: molecular mechanism of the antiproteinuric effect of pioglitazone. J Am Soc Nephrol. 2006; 17: 1624-32
|
|
|
|
|
|
25) Lebovitz HE, Dole JF, Patwardhan R, et al. Rosiglitazone monotherapy is effective in patients with type 2 diabetes. J Clin Endocrinol Metab. 2001; 86: 280-8
|
|
|
|
|
|
26) Nakamura T, Ushiyama C, Suzuki S, et al. Effect of troglitazone on urinary albumin excretion and serum type IV collagen concentrations in Type 2 diabetic patients with microalbuminuria or macroalbuminuria. Diabet Med. 2001; 18: 308-13
|
|
|
|
|
|
27) Haber DA, Sohn RL, Buckler AJ, et al. Alternative splicing and genomic structure of the Wilms tumor gene WT1. Proc Natl Acad Sci U S A. 1991; 88: 9618-22
|
|
|
|
|
|
28) Bruening W, Pelletier J. A non-AUG translational initiation event generates novel WT1 isoforms. J Biol Chem. 1996; 271: 8646-54
|
|
|
|
|
|
29) Scharnhorst V, Kranenburg O, van der Eb AJ, et al. Differential regulation of the Wilms' tumor gene, WT1, during differentiation of embryonal carcinoma and embryonic stem cells. Cell Growth Differ. 1997; 8: 133-43
|
|
|
|
|
|
30) Armstrong JF, Pritchard-Jones K, Bickmore WA, et al. The expression of the Wilms' tumour gene, WT1, in the developing mammalian embryo. Mech Dev. 1993; 40: 85-97
|
|
|
|
|
|
31) Kreidberg JA, Sariola H, Loring JM, et al. WT-1 is required for early kidney development. Cell. 1993; 74: 679-91
|
|
|
|
|
|
32) Moore AW, McInnes L, Kreidberg J, et al. YAC complementation shows a requirement for Wt1 in the development of epicardium, adrenal gland and throughout nephrogenesis. Development. 1999; 126: 1845-57
|
|
|
|
|
|
33) Patek CE, Little MH, Fleming S, et al. A zinc finger truncation of murine WT1 results in the characteristic urogenital abnormalities of Denys-Drash syndrome. Proc Natl Acad Sci U S A. 1999; 96: 2931-6
|
|
|
|
|
|
34) Ito S, Ikeda M, Takata A, et al. Nephrotic syndrome and end-stage renal disease with WT1 mutation detected at 3 years. Pediatr Nephrol. 1999; 13: 790-1
|
|
|
|
|
|
35) Yang Y, Jeanpierre C, Dressler GR, et al. WT1 and PAX-2 podocyte expression in Denys-Drash syndrome and isolated diffuse mesangial sclerosis. Am J Pathol. 1999; 154: 181-92
|
|
|
|
|
|
36) Wagner N, Wagner KD, Xing Y, et al. The major podocyte protein nephrin is transcriptionally activated by the Wilms' tumor suppressor WT1. J Am Soc Nephrol. 2004; 15: 3044-51
|
|
|
|
|
|
37) Caricasole A, Duarte A, Larsson SH, et al. RNA binding by the Wilms tumor suppressor zinc finger proteins. Proc Natl Acad Sci U S A. 1996; 93: 7562-6
|
|
|
|
|
|
38) Laity JH, Dyson HJ, Wright PE. Molecular basis for modulation of biological function by alternate splicing of the Wilms' tumor suppressor protein. Proc Natl Acad Sci U S A. 2000; 97: 11932-5
|
|
|
|
|
|
39) Gessler M, Poustka A, Cavenee W, et al. Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping. Nature. 1990; 343: 774-8
|
|
|
|
|
|
40) Boulay JL, Dennefeld C, Alberga A. The Drosophila developmental gene snail encodes a protein with nucleic acid binding fingers. Nature. 1987; 330: 395-8
|
|
|
|
|
|
41) Ikenouchi J, Matsuda M, Furuse M, et al. Regulation of tight junctions during the epithelium-mesenchyme transition: direct repression of the gene expression of claudins/occludin by Snail. J Cell Sci. 2003; 116: 1959-67
|
|
|
|
|
|
42) Ohkubo T, Ozawa M. The transcription factor Snail downregulates the tight junction com-ponents independently of E-cadherin down-regulation. J Cell Sci. 2004; 117: 1675-85
|
|
|
|
|
|
43) Matsui I, Ito T, Kurihara H, et al. Snail, a transcriptional regulator, represses nephrin expression in glomerular epithelial cells of nephrotic rats. Lab Invest. 2007; 87: 273-83
|
|
|
|
|
|
44) Nieto MA. The snail superfamily of zinc-finger transcription factors. Nat Rev Mol Cell Biol. 2002; 3: 155-66
|
|
|
|
|
|
45) Markowitz GS, Radhakrishnan J, Kambham N, et al. Lithium nephrotoxicity: a progressive combined glomerular and tubulointerstitial nephropathy. J Am Soc Nephrol. 2000; 11: 1439-48
|
|
|
|
|