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2)Rodriguez-Iturbe B, Pons H, Quiroz Y, et al. Autoimmunity in the pathogenesis of hypertension. Nat Rev Nephrol. 2014; 10: 56-62
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3)McMaster WG, Kirabo A, Madhur MS, et al. Inflammation, immunity, and hypertensive end-organ damage. Circ Res. 2015; 116: 1022-33
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4)Idris-Khodja N, Mian MOR, Paradis P, et al. Dual opposing roles of adaptive immunity in hypertension. Eur Heart J. 2014; 35: 1238-44
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5)Dange RB, Agarwal D, Masson GS, et al. Central blockade of TLR4 improves cardiac function and attenuates myocardial inflammation in angiotensin II-induced hypertension. Cardiovasc Res. 2014; 103: 17-27
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6)Dange RB, Agarwal D, Teruyama R, et al. Toll-like receptor 4 inhibition within the paraventricular nucleus attenuates blood pressure and inflammatory response in a genetic model of hypertension. J Neuroinflammation. 2015; 12: 31
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7)Ogawa K, Hirooka Y, Kishi T, et al. Brain AT1 receptor activates the sympathetic nervous system through toll-like receptor 4 in mice with heart failure. J Cardiovasc Pharmacol. 2011; 58: 543-9
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8)Ogawa K, Hirooka Y, Kishi T, et al. Partially silencing brain toll-like receptor 4 prevents in part left ventricular remodeling with sympathoinhibition in rats with myocardial infarction-induced heart failure. PLos One. 2013; 8: e69053
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9)Singh MV, Cicha MZ, Meyerholz DK, et al. Dual activation of TRIF and MyD88 adaptor proteins by angiotensin II evokes opposing effects on pressure, cardiac hypertrophy, and inflammatory gene expression. Hypertension. 2015; 66: 647-56
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10)Masson GS, Nair AR, Soares PPS, et al. Aerobic training normalizes autonomic dysfunction, HMGB1 content, microglia activation and inflammation in hypothalamic paraventricular nucleus of SHR. Am J Physiol Heart Circ Physiol. 2015; 309: H1115-H22
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11)Guzik TJ, Hoch NE, Brown KA, et al. Role of the T cell in the genesis of angiotensin II induced hypertension and vascular dysfunction. J Exp Med. 2007; 204: 2449-60
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12)Marvar PJ, Thabet SR, Guzik TJ, et al. Central and peripheral mechanisms of T-lymphocyte activation and vascular inflammation produced by angiotensin II-induced hypertension. Circ Res. 2010; 107: 263-70
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13)Kirabo A, Fontana V, de Faria APC, et al. DC isoketal-modified proteins activate T cells and promote hypertension. J Clin Invest. 2014; 124: 4642-56
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14)Shen XZ, Li Y, Shah KH, et al. Micoglia participate in neurogenic regulation of hypertension. Hypertension. 2015; 66: 309-16
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15)Santisteban MM, Ahmari N, Carvajal JM, et al. Involvement of bone marrow cells and neuroinflammation in hypertension. Circ Res. 2015; 117: 178-91
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16)Wei S-G, Yu Y, Zhang Z-H, et al. Proinflammatory cytokines upregulate sympathoexcitatory mechanisms in the subfornical organ of the rat. Hypertension. 2015; 65: 1126-33
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17)Shinohara K, Kishi T, Hirooka Y, et al. Circulating angiotensin II deteriorates left ventricular function with sympathoexcitation via brain angiotensin II receptor. Physiol Rep. 2015; 3: e12514
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18)Xiao L, Kirabo A, Wu J, et al. Renal denervation prevents immune cell activation and renal inflammation in angiotensin II-induced hypertension. Circ Res. 2015; 117: 547-57
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19)Katsuki M, Hirooka Y, Kishi T, et al. Decreased proportion of Foxp3+CD4+ regulatory T cells contributes to the development of hypertension in genetically hypertensive rats. J Hypertens. 2015; 33: 773-83
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20)Young CN, Davisson RL. Angiotensin-II, the brain, and hypertension. An update. Hypertension. 2015; 66: 920-6
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