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1) Ota T, Takamura T, Hirai N, et al. Preobesity in world health organization classification involves the metabolic syndrome in Japanese. Diabetes Care. 2002; 25: 1252-3
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2) 太田嗣人, 山上孝司, 櫻井 勝, 他. 日本人で代謝異常が増大するBMI. 肥満研究(日本肥満学会誌). 2005; 11: 317-22
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3) Sakurai M, Takamura T, Ota T, et al. Liver steatosis, but not fibrosis, is associated with insulin resistance in nonalcoholic fatty liver disease. J Gastroenterol. 2007; 42: 312-7
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4) Takamura T, Misu H, Yamashita T, et al. SAGE application in the study of diabetes. Curr Pharm Biotechnol. 2008; 9: 392-9
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5) Takamura T, Sakurai M, Ota T, et al. Genes for systemic vascular complications are differentially expressed in the livers of type 2 diabetic patients. Diabetologia. 2004; 47: 638-47
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6) Takeshita Y, Takamura T, Hamaguchi E, et al. Tumor necrosis factor-alpha-induced production of plasminogen activator inhibitor 1 and its regulation by pioglitazone and cerivastatin in a nonmalignant human hepatocyte cell line. Metabolism. 2006; 55: 1464-72
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7) Takeshita Y, Takamura T, Minato H, et al. Transformation of p53-positive papillary thyroid carcinoma to anaplastic carcinoma of the liver following postoperative radioactive iodine-131 therapy. Intern Med. 2008; 47: 1709-12
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8) Kita Y, Mizukoshi E, Takamura T, et al. Impact of diabetes mellitus on prognosis of patients infected with hepatitis C virus. Metabolism. 2007; 56: 1682-8
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9) Komura T, Mizukoshi E, Kita Y, et al. Impact of diabetes on recurrence of hepatocellular carcinoma after surgical treatment in patients with viral hepatitis. Am J Gastroenterol. 2007; 102: 1939-46
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10) Hamaguchi E, Takamura T, Sakurai M, et al. Histological course of nonalcoholic fatty liver disease in Japanese patients: tight glycemic control, rather than weight reduction, ameliorates liver fibrosis. Diabetes Care. 2010; 33: 284-6
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11) Shimizu A, Takamura T, Matsuzawa N, et al. Regulation of adiponectin receptor expression in human liver and a hepatocyte cell line. Metabolism. 2007; 56: 1478-85
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12) Misu H, Takamura T, Matsuzawa N, et al. Genes involved in oxidative phosphorylation are coordinately upregulated with fasting hyperglycaemia in livers of patients with type 2 diabetes. Diabetologia. 2007; 50: 268-77
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13) Takamura T, Misu H, Matsuzawa-Nagata N, et al. Obesity upregulates genes involved in oxidative phosphorylation in livers of diabetic patients. Obesity (Silver Spring). 2008; 16: 2601-9
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14) Mootha VK, Lindgren CM, Eriksson KF, et al. PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet. 2003; 34: 267-73
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15) Dahlman I, Forsgren M, Sjogren A, et al. Downregulation of electron transport chain genes in visceral adipose tissue in type 2 diabetes independent of obesity and possibly involving tumor necrosis factor-α. Diabetes. 2006; 55: 1792-9
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16) Takamura T, Honda M, Sakai Y, et al. Gene expression profiles in peripheral blood mononuclear cells reflect the pathophysiology of type 2 diabetes. Biochem Biophys Res Commun. 2007; 361: 379-84
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17) Pospisilik JA, Knauf C, Joza N, et al. Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes. Cell. 2007; 131: 476-91
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18) Selman C, Tullet JM, Wieser D, et al. Ribosomal protein S6 kinase 1 signaling regulates mammalian life span. Science. 2009; 326: 140-4
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19) Kalender A, Selvaraj A, Kim SY, et al. Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner. Cell Metab. 2010; 11: 390-401
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20) Kapahi P, Vijg J. Aging--lost in translation? N Engl J Med. 2009; 361: 2669-70
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21) Misu H, Takamura T, Takayama H, et al. A liver-derived secretory protein, selenoprotein P, causes insulin resistance. Cell Metab. 2010; 12: 483-95
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22) Ando H, Yanagihara H, Hayashi Y, et al. Rhythmic messenger ribonucleic acid expression of clock genes and adipocytokines in mouse visceral adipose tissue. Endocrinology. 2005; 146: 5631-6
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23) Ando H, Takamura T, Matsuzawa-Nagata N, et al. The hepatic circadian clock is preserved in a lipid-induced mouse model of non-alcoholic steatohepatitis. Biochem Biophys Res Commun. 2009; 380: 684-8
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24) Ando H, Ushijima K, Yanagihara H, et al. Clock gene expression in the liver and adipose tissues of non-obese type 2 diabetic Goto-Kakizaki rats. Clin Exp Hypertens. 2009; 31: 201-7
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25) Ando H, Takamura T, Matsuzawa-Nagata N, et al. Clock gene expression in peripheral leucocytes of patients with type 2 diabetes. Diabetologia. 2009; 52: 329-35
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