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1)Askar S, Weber GF, Panoutsakopoulou V, et al. Eta-1(osteopontin): an early component of type-1 (cell-mediated) immunity. Science. 2000; 287: 860-4
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2)Chabas D, Baranzini SE, Mitchell D, et al. The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease. Science. 2001; 294: 1731-5
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3)Weiss JM, Renkl AC, Maier CS, et al. Osteopontin is involved in the initiation of cutaneous contact hypersensitivity by inducing Langerhans and dendritic cell migration to lymph nodes. J Exp Med. 2001; 194: 1219-29
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4)Ohshima S, Yamaguchi N, Nishioka K, et al. Enhanced local production of osteopontin in rheumatoid joints. J Rheumatol. 2002; 29: 2061-77
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5)Yamamoto N, Sakai F, Kon S, et al. Essential role of the cryptic epitope SLAYGLR within osteopontin in a murine model of rheumatoid arthritis. J Clin Invest. 2003; 112: 181-8
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6)Gravallese EM. Osteopontin: a bridge between bone and the immune system. J Clin Invest. 2003; 112: 147-9
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7)Diao H, Kon S, Iwabuchi K, et al. Osteopontin as a mediator of NKT cell function in T cell-mediated liver diseases. Immunity. 2004; 21: 539-50
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8)Sato T, Nakai T, Tamura N, et al. Osteopontin/Eta-1 upregulated in Crohn's disease regulated the Th1 immune response. Gut. 2005; 54: 1254-62
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9)Kitamura M, Iwabuchi K, Kitaichi N, et al. Osteopontin aggravates experimental autoimmune uveoretinis in mice. J Immunol. 2007; 178: 6567-72
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10)Denhardt DT, Guo X. Osteopontin: a protein with diverse functions. FASEB J. 1993; 7: 1475-82
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11)Uede T, Katagiri Y, Iizuka J, et al. Osteopontin, a coordinator of host defense system; a cytokine or an extracellular matrix adhesive protein? Microbiol Immunol. 1997; 41: 641-8
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12)Yokosaki Y, Matsuura N, Sasaki T, et al. The integrin-alpha(9)beta(1) binds to a novel recognition sequence (SVVYGLR) in the thrombin-cleaved amino-terminal fragment of osteopontin. J Biol Chem. 1999; 274: 36328-34
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13)Yokasaki Y, Sheppard D. Mapping of the cryptic integrin-binding site in osteopontin suggests a new mechanism by which thrombin can regulate inflammation and tissue repair. Trends Cardiovasc Med. 2000; 10: 155-9
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14)Hur EM, Youssef S, Haws ME, et al. Osteopontin-induced relapse and progression of autoimmune brain disease through enhanced survival of activated T cells. Nat Immunol. 2007; 8: 74-83
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15)Xanthou G, Alissafi T, Semitekolou M, et al. Osteopontin has a crucial role in allergic airway disease through regulation of dendritic cell subsets. Nat Med. 2007; 13: 536-8
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16)Shirohara ML, Lu L, Bu J, et al. Ostoepontin expression is essential for interferon-alpha production by plasmacytoid dendritic cells. Nat Immunol. 2006; 7: 498-506
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17)Stier S, Ko Y, Forkert R, et al. Osteopontin is a hematopoietic stem cell niche component that negatively resultes stem cell pool size. J Exp Med. 2005; 201: 1781-91
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18)Nilsson S, Johnston HM, Genevieve A, et al. Osteopontin, a key compoment of the hematopoietic stem cell niche and regulator of primitive hepatopoietic progenitor cells. Blood. 2005; 106: 1232-9
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19)Kollet O, Dar A, Shivtiel S, et al. Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells. Nat Med. 2006; 12: 657-64
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20)Ye Q-H, Oin L-X, Forgues M, et al. Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning. Nat Med. 2003; 9: 416-23
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21)Takafuki V, Forgues M, Unsworth E, at al. An osteopontin fragment is essential for tumor cell invasion in hepatocellular carcinoma. Oncogene. 2007; 26: 6361-71
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22)Mi Z, Oliver T, Guo H, et al. Thrombin-cleaved COOH-terminal osteopontin peptide binds with cyclophilin C to CD147 in murine breast cancer cells. Cancer Res. 2007; 67: 4088-97
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23)Matsui Y, Jia N, Okamoto H, et al. Role of osteopontin in cardiac fibrosis and remodeling in angiotensin II-induced cardiac hypertrophy. Hypertension. 2004; 43: 1195-201
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24)Diez J. Profibrotic effects of angiotensin in the heart. A mater of mediators. Hypertension. 2004; 43: 1164-5
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25)Mori N, Majima T, Iwasaki N, et al. The role of osteopontin in tendon tissue remodeling after denervation-induced mechanical stress deprivation. Mat Biol. 2007; 26: 42-53
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